Flávio de Queiroz Telles Filho

Consenso em paracoccidioidomicose

1.Departamento de Molestias Infecciosas e Parasitarias da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP. 2. Departamento de Saude Comunitaria da Universidade Federal do Parana, Curitiba, PR. 3. Departamento de Doencas Tropicais e Diagnostico por Imagem da Faculdade de Medicina Botucatu da Universidade Estadual de Sao Paulo, Sao Paulo, SP. 4. Departamento de Medicina da Escola Paulista de Medicina, Sao Paulo, SP. 5. Departamento de Clinica Medica da Faculdade Ciencias Medicas da Universidade Estadual de Campinas, Campinas, SP. *Consultores do Consenso em Paracoccidioidomicose: Adriana Kono, Antonia Terezinha Tresoldi, Bodo Wanke, Carlos Roberto Carvalho, Gil Benard, Luiz Carlos Severo, Marcelo Simao Ferreira, Mario Leon Silva Vergara, Roberto Martinez, Rogerio Jesus Pedro, Silvio Alencar Marques, Zarifa Khoury. Patrocinio sem conflito de interesse com entidades privadas: Sociedade Brasileira de Medicina Tropical, Sociedade Brasileira de Infectologia e Sociedade Paulista de Infectologia. Endereco para correspondencia: Dra. Maria Aparecida Shikanai-Yasuda. Laboratorio de Imunologia. Av. Eneias de Carvalho Aguiar 500, Terreo, Sala 4, 05403-000 Sao Paulo, Brasil. Tel: 11 3066-7048, Fax:11 3069-7507 e-mail: lim48imuno@yahoo.com.br Recebido para publicacao em 20/5/2006 Aceito em 2/6/2006 1. INTRODUCAOUniversidade de Sao Paulo Faculdade de Medicina Departamento de Molestias Infecciosas e Parasitarias

Paracoccidioidomycosis in children with different skeletal involvement

The rarity of paracoccidioidomycosis in childhood prompted us to report two cases with different clinical and radiological skeletal involvement. The number of osteolytic lesions, the presence of periosteal reaction and the finding of Paracoccidioides brasiliensis in biopsy specimens, were distinctive features in both cases.

Subcutaneous mucormycosis caused by Rhizopus oryzae: probable nosocomial acquired infection

The Authors present a case of subcutaneous mucormycosis occurring in a patient with clinical and biochemical evidence of diabetic ketoacidosis. The clinical, mycological and histopathological features are described, emphasizing the relevance of a rapid diagnosis in order to stablish early treatment. The clinical forms of mucormycosis and the main associated conditions are briefly reviewed as well as the most probable conditions which may lead to the enhanced susceptibility to infection in the diabetic patient in ketoacidosis. The recovery of Rhizopus oryzae from the air of the room of the patient suggests a nosocomial infection acquired through contamination of venous puncture site by air borne spores.

Aspectos epidemiológicos das micoses dos pés em um time chinês de futebol

As infeccoes fungicas podais podem interferir no desempenho esportivo ao provocar desconforto e dor nos atletas. O objetivo deste estudo foi avaliar a prevalencia das infeccoes fungicas podais em um time profissional de futebol, verificando os agentes mais frequentes e os fatores predisponentes. O delineamento da pesquisa foi transversal e descritivo. A amostra foi composta de 22 homens, com idades entre 23 e 36 anos, integrantes do time de futebol profissional chines, quando de sua participacao de jogos em Curitiba (PR). Todos foram avaliados clinicamente e submetidos a exames micologicos (direto e cultura) de escamas de pele e unha dos pes e estudo histopatologico de fragmento ungueal. Os resultados encontrados foram: 12 casos (54,5%) nao apresentavam micose; cinco casos (22,72%) apresentavam onicomicose isolada e cinco casos (22,72%) apresentavam onicomicose associada a tinea pedis, tendo como principal agente isolado o Trichophyton rubrum. Os fatores predisponentes apontados pelos atletas incluiram: banho em local publico (85%), pratica de esporte (76%), uso de calcados fechados (70%), contato com animal domestico (63%) e irregularidade na higiene dos pes (50%). CONCLUSAO: A frequencia da onicomicose em atletas chineses foi maior do que na populacao em geral. O agente mais frequente foi o Trichophyton rubrum. Os habitos individuais podem contribuir para a aquisicao dessas infeccoes fungicas, alem do trauma direto pelo calcado e bola, bem como pelo contato fisico durante treinos e jogos que podem favorecer lesoes cutâneas e ungueais.Podal fungal infections can interfere in the sportive performance, since they provoke discomfort and pain in the athletes. The purpose of this study was to assess the prevalence of podal fungal infections in a professional soccer team, verifying the more frequent agents and the predisposing factors to that condition. The research had a transversal and descriptive outlining. The sampling was composed by twenty-two 23 to 36 years old male athletes from the professional Chinese soccer team on the occasion they participated in a game series in Curitiba (PR). All athletes were clinically assessed, and they were submitted to mycological examinations (direct and culture) of the skin and nails squamas from their feet, as well as to a histopathologic study of the ungual fragment. The results found were: twelve cases (54.5%) did not present mycosis; 5 cases (22.72%) presented isolated onychomycosis, and 5 cases (22.72%) presented onychomycosis associated to tinea pedis, having as major isolated agent the Trichophyton rubrum. The predisposing agents pointed by athletes included: bath in a public place (85%), sports practice (76%), use of closed shoes (70%), contact with pets (63%), and irregular feet hygiene (50%). CONCLUSION: The frequency of the onychomycosis in Chinese athletes was higher than in the general population. The most frequent agent found it was the Trichophyton rubrum. The individual habits may contribute to the acquisition of these fungal infections added to the direct trauma provoked by the shoe and the ball, as well as to the physical contact during the trainings and games that may favor the cutaneous and ungual injuries.

Draft Genome Sequence of Fonsecaea monophora Strain CBS 269.37, an Agent of Human Chromoblastomycosis.

ABSTRACT The black yeast Fonsecaea monophora is one of the main etiologic agents of chromoblastomycosis in humans. Its pathogenicity profile is more invasive than that of related Fonsecaea species, causing brain infection in addition to (sub)cutaneous infections.

Aspectos epidemiologicos de las micosis de los pies en un equipo chino de fútbol

As infeccoes fungicas podais podem interferir no desempenho esportivo ao provocar desconforto e dor nos atletas. O objetivo deste estudo foi avaliar a prevalencia das infeccoes fungicas podais em um time profissional de futebol, verificando os agentes mais frequentes e os fatores predisponentes. O delineamento da pesquisa foi transversal e descritivo. A amostra foi composta de 22 homens, com idades entre 23 e 36 anos, integrantes do time de futebol profissional chines, quando de sua participacao de jogos em Curitiba (PR). Todos foram avaliados clinicamente e submetidos a exames micologicos (direto e cultura) de escamas de pele e unha dos pes e estudo histopatologico de fragmento ungueal. Os resultados encontrados foram: 12 casos (54,5%) nao apresentavam micose; cinco casos (22,72%) apresentavam onicomicose isolada e cinco casos (22,72%) apresentavam onicomicose associada a tinea pedis, tendo como principal agente isolado o Trichophyton rubrum. Os fatores predisponentes apontados pelos atletas incluiram: banho em local publico (85%), pratica de esporte (76%), uso de calcados fechados (70%), contato com animal domestico (63%) e irregularidade na higiene dos pes (50%). CONCLUSAO: A frequencia da onicomicose em atletas chineses foi maior do que na populacao em geral. O agente mais frequente foi o Trichophyton rubrum. Os habitos individuais podem contribuir para a aquisicao dessas infeccoes fungicas, alem do trauma direto pelo calcado e bola, bem como pelo contato fisico durante treinos e jogos que podem favorecer lesoes cutâneas e ungueais.Podal fungal infections can interfere in the sportive performance, since they provoke discomfort and pain in the athletes. The purpose of this study was to assess the prevalence of podal fungal infections in a professional soccer team, verifying the more frequent agents and the predisposing factors to that condition. The research had a transversal and descriptive outlining. The sampling was composed by twenty-two 23 to 36 years old male athletes from the professional Chinese soccer team on the occasion they participated in a game series in Curitiba (PR). All athletes were clinically assessed, and they were submitted to mycological examinations (direct and culture) of the skin and nails squamas from their feet, as well as to a histopathologic study of the ungual fragment. The results found were: twelve cases (54.5%) did not present mycosis; 5 cases (22.72%) presented isolated onychomycosis, and 5 cases (22.72%) presented onychomycosis associated to tinea pedis, having as major isolated agent the Trichophyton rubrum. The predisposing agents pointed by athletes included: bath in a public place (85%), sports practice (76%), use of closed shoes (70%), contact with pets (63%), and irregular feet hygiene (50%). CONCLUSION: The frequency of the onychomycosis in Chinese athletes was higher than in the general population. The most frequent agent found it was the Trichophyton rubrum. The individual habits may contribute to the acquisition of these fungal infections added to the direct trauma provoked by the shoe and the ball, as well as to the physical contact during the trainings and games that may favor the cutaneous and ungual injuries.

Epidemiological aspects of the feet mycosis in a Chinese soccer team

As infeccoes fungicas podais podem interferir no desempenho esportivo ao provocar desconforto e dor nos atletas. O objetivo deste estudo foi avaliar a prevalencia das infeccoes fungicas podais em um time profissional de futebol, verificando os agentes mais frequentes e os fatores predisponentes. O delineamento da pesquisa foi transversal e descritivo. A amostra foi composta de 22 homens, com idades entre 23 e 36 anos, integrantes do time de futebol profissional chines, quando de sua participacao de jogos em Curitiba (PR). Todos foram avaliados clinicamente e submetidos a exames micologicos (direto e cultura) de escamas de pele e unha dos pes e estudo histopatologico de fragmento ungueal. Os resultados encontrados foram: 12 casos (54,5%) nao apresentavam micose; cinco casos (22,72%) apresentavam onicomicose isolada e cinco casos (22,72%) apresentavam onicomicose associada a tinea pedis, tendo como principal agente isolado o Trichophyton rubrum. Os fatores predisponentes apontados pelos atletas incluiram: banho em local publico (85%), pratica de esporte (76%), uso de calcados fechados (70%), contato com animal domestico (63%) e irregularidade na higiene dos pes (50%). CONCLUSAO: A frequencia da onicomicose em atletas chineses foi maior do que na populacao em geral. O agente mais frequente foi o Trichophyton rubrum. Os habitos individuais podem contribuir para a aquisicao dessas infeccoes fungicas, alem do trauma direto pelo calcado e bola, bem como pelo contato fisico durante treinos e jogos que podem favorecer lesoes cutâneas e ungueais.Podal fungal infections can interfere in the sportive performance, since they provoke discomfort and pain in the athletes. The purpose of this study was to assess the prevalence of podal fungal infections in a professional soccer team, verifying the more frequent agents and the predisposing factors to that condition. The research had a transversal and descriptive outlining. The sampling was composed by twenty-two 23 to 36 years old male athletes from the professional Chinese soccer team on the occasion they participated in a game series in Curitiba (PR). All athletes were clinically assessed, and they were submitted to mycological examinations (direct and culture) of the skin and nails squamas from their feet, as well as to a histopathologic study of the ungual fragment. The results found were: twelve cases (54.5%) did not present mycosis; 5 cases (22.72%) presented isolated onychomycosis, and 5 cases (22.72%) presented onychomycosis associated to tinea pedis, having as major isolated agent the Trichophyton rubrum. The predisposing agents pointed by athletes included: bath in a public place (85%), sports practice (76%), use of closed shoes (70%), contact with pets (63%), and irregular feet hygiene (50%). CONCLUSION: The frequency of the onychomycosis in Chinese athletes was higher than in the general population. The most frequent agent found it was the Trichophyton rubrum. The individual habits may contribute to the acquisition of these fungal infections added to the direct trauma provoked by the shoe and the ball, as well as to the physical contact during the trainings and games that may favor the cutaneous and ungual injuries.