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Dive into the research topics where Florence C. E. Saraber is active.

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Featured researches published by Florence C. E. Saraber.


Tetrahedron | 2003

A new approach toward the synthesis of C,D-cis coupled steroid and C,D-cis coupled D-homosteroid skeletons

Svetlana Dratch; Tanya Charnikhova; Florence C. E. Saraber; B. J. M. Jansen; Aede de Groot

A short and efficient procedure has been developed for the synthesis of C,D-cis coupled steroid and D-homo steroid skeletons. A Mukaiyama reaction with transfer of the silyl group of the starting silyl enol ether to the enol of the adduct followed by addition of vinyl magnesium bromide to the unprotected carbonyl group leads to adducts which can be cyclized with ZnBr2. The synthesis of functionalized steroid skeletons in overall yields of about 50% in four steps can be achieved in this way


Tetrahedron | 2006

Synthesis of a chiral steroid ring D precursor starting from carvone

Serghei Pogrebnoi; Florence C. E. Saraber; B. J. M. Jansen; Aede de Groot


Tetrahedron | 2006

New approaches toward the synthesis of (D-homo) steroid skeletons using Mukaiyama reactions

Florence C. E. Saraber; Alexander Baranovsky; B. J. M. Jansen; Maarten A. Posthumus; Aede de Groot


Tetrahedron | 2006

Domino Mukaiyama-Michael reactions in the synthesis of polycyclic systems

Florence C. E. Saraber; Svetlana Dratch; Geke Bosselaar; B. J. M. Jansen; Aede de Groot


Tetrahedron | 2006

Ring C closure as key step in the synthesis of steroids

Florence C. E. Saraber; Aede de Groot


Tetrahedron Letters | 2004

A new flexible synthesis of (D-homo) steroids

Florence C. E. Saraber; Aede de Groot


Arkivoc | 2005

Annelations of cyclic Beta-cyanoketones in the synthesis of functionalized polycyclic compounds and steroids

Arkady Sobolev; Martin Vos; Han Zuilhof; Florence C. E. Saraber; B. J. M. Jansen; Aede de Groot


Polish Journal of Chemistry | 2006

Mukaiyama and torgov chemistry in the synthesis of (D-homo) steroid skeletons

Florence C. E. Saraber; Svetlana V. Drach; Alexander Baranovsky; Tanya Charnikhova; Serghei Pogrebnoi; B. J. M. Jansen; Aede de Groot


Tetrahedron | 2006

1-Phenylthio-3-vinyl-3-cyclohexenol, a new reagent for bis-annelation of silyl enol ethers

Olga Konstantinova; Florence C. E. Saraber; Enrique Melguizo; B. J. M. Jansen; Aede de Groot


Journal of the American Chemical Society | 2005

17-Isopropyl-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene

Huub Kooijman; Florence C. E. Saraber; Ae. de Groot; Anthony L. Spek

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Aede de Groot

Wageningen University and Research Centre

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B. J. M. Jansen

Wageningen University and Research Centre

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Alexander Baranovsky

Wageningen University and Research Centre

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Serghei Pogrebnoi

Wageningen University and Research Centre

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Tanya Charnikhova

Wageningen University and Research Centre

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Geke Bosselaar

Wageningen University and Research Centre

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Maarten A. Posthumus

Wageningen University and Research Centre

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Olga Konstantinova

Wageningen University and Research Centre

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