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Dive into the research topics where Florian Gras is active.

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Featured researches published by Florian Gras.


Foot & Ankle International | 2011

Short-Term Outcome of Retrograde Tibiotalocalcaneal Arthrodesis with a Curved Intramedullary Nail

Thomas Mückley; Kajetan Klos; Thomas Drechsel; Claudia Beimel; Florian Gras; Gunther O. Hofmann

Background: The aim of this study was to investigate the potential clinical benefit of tibiotalocalcaneal arthrodesis (TTCA) with an intramedullary nail with a valgus curve, two compression options, and angle-stable locking. Material and Methods: Patients who had undergone TTCA at two tertiary hospitals were eligible. Patients who had undergone TTCA before the beginning of the study were evaluated retrospectively, then all following patients were examined prospectively. There were 59 TTCAs; 55 patients were available for analysis. Twenty-eight were evaluated retrospectively, 27 prospectively. Main Outcome Measures were an SF-36, Mazur-, and AOFAS ankle-hindfoot rating scores and radiographic examination. Results: Bony union was obtained in 53 patients. Fifty-one patients were satisfied with the outcome. Fifty-one patients had marked subjective improvement in mobility. The mean AOFAS score of the 55 patients at the latest followup was 66.8 (range, 38 to 86). The mean Mazzur score was 68.0 (range, 30 to 83). In the prospective group, the scores were significantly improved: AOFAS score by an average of 39.6 points (p < 0.001); Mazur score by an average of 43 points (p < 0.001); SF-36 physical component summary score (p < 0.001) and mental component summary score also improved (p < 0.048). Radiology showed good hind-foot alignment. The complication rate was 25%. Conclusion: Compared with the literature, the data obtained in this study show a good outcome and a high rate of bony union, with comparable complication rates. Patient satisfaction was good. However, the patients still had limitations. The clinical benefit of the nail used was confirmed. Level of Evidence: IV, Case Series


BMC Musculoskeletal Disorders | 2010

2D-fluoroscopic navigated percutaneous screw fixation of pelvic ring injuries - a case series

Florian Gras; Ivan Marintschev; Arne Wilharm; Kajetan Klos; Thomas Mückley; Gunther O. Hofmann

BackgroundScrew fixation of pelvic ring fractures is a common, but demanding procedure and navigation techniques were introduced to increase the precision of screw placement. The purpose of this case series was the evaluation of screw misplacement rate and functional outcome of percutaneous screw fixation of pelvic ring disruptions using a 2D navigation system.MethodsBetween August 2004 and December 2007, 44 of 442 patients with pelvic injuries were included for closed reduction and percutaneous screw fixation of disrupted pelvic ring lesions using an optoelectronic 2D-fluoroscopic based navigation system. Operating and fluoroscopy time were measured, as well as peri- and postoperative complications documented. Screw position was assessed by postoperative CT scans. Quality of live was evaluated by SF 36-questionnaire in 40 of 44 patients at mean follow up 15.5 ± 1.2 month.Results56 iliosacral- and 29 ramus pubic-screws were inserted (mean operation time per screw 62 ± 4 minutes, mean fluoroscopy time per screw 123 ± 12 seconds). In post-operative CT-scans the screw position was assessed and graded as follows: I. secure positioning, completely in the cancellous bone (80%); II. secure positioning, but contacting cortical bone structures (14%); III. malplaced positioning, penetrating the cortical bone (6%). The malplacements predominantly occurred in bilateral overlapping screw fixation. No wound infection or iatrogenic neurovascular damage were observed. Four re-operations were performed, two of them due to implant-misplacement and two of them due to implant-failure.Conclusion2D-fluoroscopic navigation is a safe tool providing high accuracy of percutaneous screw placement for pelvic ring fractures, but in cases of a bilateral iliosacral screw fixation an increased risk for screw misplacement was observed. If additional ramus pubic screw fixations are performed, the retrograde inserted screws have to pass the iliopubic eminence to prevent an axial screw loosening.


Injury-international Journal of The Care of The Injured | 2012

Biomechanical comparison of different acetabular plate systems and constructs - The role of an infra-acetabular screw placement and use of locking plates §

Ivan Marintschev; Florian Gras; Christoph E. Schwarz; Tim Pohlemann; Gunther O. Hofmann; Ulf Culemann

INTRODUCTION The aim of this study was the direct comparison of the static fixation strength of two common plate systems: MPS (Matta Pelvic System) and LPPS (Low Profile Plate System). Furthermore the role of a modified screw placement with addressing the infra-acetabular corridor and the use of locking screws were evaluated. MATERIALS AND METHODS Custom made anterior column fractures in artificial SYNBONE pelves were fixed with different acetabular plates (group I: MPS, group II: LPPS none locking and group III: LPPS locking). Each pelvis was tested twice, with the additionally placed infra-acetabular lag screw [+] first, followed by a repeated measurement without the infra-acetabular screw [-]. Six pelves per group were tested under static loading with six cycles up to 800N, each. The fracture displacement was measured in the weight bearing dome using an ultrasound based Zebris-3D-Motion Analyzer. RESULTS The MPS-plate had a less fixation strength compared to the LPPS-plate (mean±SD of maximum fracture displacement [mm] in group I vs. group II=0.63±0.02 vs. 0.37±0.02, p<0.05). The locking feature did not increase the fracture fixation strength (mean±SD of maximum fracture displacement [mm] in group II vs. group III: 0.37±0.02 vs. 0.37±0.03; ns). The infra-acetabular screw significantly reduces the maximum fracture displacement in all groups, independent of the plate systems ([Delta%] in group I=50; group II=63 and group III=40; p<0.05 each). CONCLUSION The LPPS-plate performed superior fixation strength for anterior column fractures compared to the MPS-plate. The locking plate modality did not reduce the maximum fracture displacement, whereas the additional infra-acetabular screw placement actually doubles the fracture fixation strength independent of the used plate system.


Journal of Orthopaedic Trauma | 2012

Screw placement for acetabular fractures: which navigation modality (2-dimensional vs. 3-dimensional) should be used? An experimental study.

Florian Gras; Ivan Marintschev; Kajetan Klos; Thomas Mückley; Gunther O. Hofmann; David M. Kahler

Objectives: Screw navigation techniques with different image guidance [2-dimensional (2D) vs. 3-dimensional (3D) fluoroscopy] were evaluated for acetabular fracture surgery. Methods: Two-dimensional and 3D navigation images were analyzed for visualization of different osseous corridors: supra-acetabular, anterior column, posterior column, and infra-acetabular. Forty guide wires per group were placed in synthetic pelvis with a prefabricated soft tissue envelope (10 per group) using a 2D or 3D fluoroscopic navigation procedure. Duration of the single steps for each procedure and of cumulative fluoroscopy time was measured. The accuracy of guide wire placement was evaluated visually and in 3D cone-beam scans. Results: The overall procedure time per pelvis was significantly reduced in the 3D group compared with the 2D group [mean ± standard error (SE) (minutes): 50.11 ± 1.38 vs. 63.42 ± 2.32; P < 0.0001]. A trend to reduction in image acquisition time [mean ± SE (minutes): 12.37 ± 1.34 vs. 15.43 ± 1.03; P = not significant] and significant increase in the cumulative fluoroscopy time [mean ± SE (seconds): 64 ± 9 vs. 13 ± 1.3; P < 0.0001) was measured in the 3D compared with the 2D group, caused by the 3D scan. Intra-articular misplacements were not observed in both the groups, but an increased accuracy could be achieved using the 3D image–based navigation procedure (perfect placement: 37 vs. 29; secure placement: 2 vs. 7; misplacement: 1 vs. 4). Conclusions: Both navigation procedures securely prevent an intra-articular penetration during drilling, but the 3D image–based navigation procedure increases the overall accuracy compared with the 2D image–based navigation technique (misplacement rates of 2.5% vs. 10%). Especially, in very narrow corridors (as the infra-acetabular screw path), the use of 3D navigation should be preferred.


Injury-international Journal of The Care of The Injured | 2011

Evaluation of a polyaxial angle-stable volar plate in a distal radius C-fracture model – A biomechanical study

Sascha Rausch; Kajetan Klos; Helen Stephan; Konrad L. Hoffmeier; Florian Gras; Markus Windolf; Boyko Gueorguiev; Gunther O. Hofmann; Thomas Mückley

INTRODUCTION Polyaxial angle-stable plating is thought to be particularly beneficial in the management of complex intra-articular fractures of the distal radius. The purpose of the present study was to investigate whether the technique provides stability to match that of conventional (fixed-angle) angle-stable constructs. MATERIAL AND METHODS In seven pairs of human cadaver radii, an Arbeitsgemeinschaft für Osteosynthese (AO) 23 C2.1 intra-articular fracture was created. One radius of each pair received a juxta-articular 2.4-mm locking compression plate (LCP) Volar Distal Radius Plate, whilst the contralateral one received a 2.4-mm Variable Angle Locking Compression Plate (LCP) Two-Column Volar Distal Radius Plate (both plates: Synthes, Oberdorf, Switzerland). Parameters tested were construct stiffness (static axial loading with 150 N), range of motion and secondary loss of reduction (dynamic 150 N axial loading over 5000 cycles). Stiffness and range of motion were measured both pre- and post-cycling. RESULTS The polyaxial constructs were significantly stiffer, both before and after cyclic testing. However, the two-column plates showed a significant loss of stiffness during cyclic testing. The range of motion was significantly greater, both initially and at the end of cyclic testing, in the fixed-angle constructs. The conventional constructs had significantly greater secondary loss of reduction. CONCLUSION The polyaxial two-column plate tested in this study provides a biomechanically sound construct for the management of intra-articular fractures of the distal radius.


Injury-international Journal of The Care of The Injured | 2011

Navigation in femoral-shaft fractures--from lab tests to clinical routine.

A. Wilharm; Florian Gras; Sascha Rausch; R. Linder; Ivan Marintschev; Gunther O. Hofmann; Thomas Mückley

INTRODUCTION This study evaluates the use of a navigation system (BrainLAB, Feldkirchen, Germany) to intra-operatively check for correct length, axis and rotation in intramedullary nailing of femoral-shaft fractures in an experimental setting and in clinical routine. MATERIALS AND METHODS We tested the navigation system in two experimental settings before introducing it into clinical routine. In the first experiment, 10 osteotomised model femora were fixed with intramedullary nails by using a navigation system. The goal was a locking fixation in predefined values for length and rotation. In the second experiment, eight examiners assessed values for rotation and length of one femur 10 times to examine the accuracy and reproducibility of that determination. Following this, we navigated 40 femoral nailing procedures in our department. Preoperatively, we assessed values of femur geometry on the contralateral side in a computed tomography (CT) scan and reproduced these values intra-operatively on the fractured side, guided by the navigation system. During the intervention, we recorded the length of the procedure steps and the fluoroscopy time. We verified the intra-operative values achieved with the navigation system in a postoperative CT scan and documented differences in rotation and length. After the assessment, we analysed the data for different findings on femur geometry, fluoroscopy time and procedure duration. RESULTS The experimental evaluation showed a range of ±5° for anteversion differences and ±2.3 mm for length differences. We estimated this accuracy as sufficient to use the system in clinical routine. The navigation system was used for 40 fracture fixations. All our criteria for restoring femoral geometry could be achieved by navigation guidance in these procedures. Setting up the system took on average 33±11.5 min. An additional fluoroscopy time of 36±22 s was needed to acquire the reference X-rays and to verify pin placement. The differences between anteversion values assessed in intra-operative planning steps on the navigation system and values assessed with a postoperative CT were on average 5.4±3.5°, whilst femur length differed on average by 4±4 mm. DISCUSSION Many authors judge intra-operative control of anteversion in femoral-shaft fracture fixation as problematic. Neither our experimental navigation assessment nor our clinical navigated evaluation showed relevant anteversion differences to a postoperative CT assessment of femur geometry. After initial training, guidance by a navigation system achieves consistent results in a clinical situation. CONCLUSIONS The use of a navigation system to align axis, length and rotation led to a secure way of avoiding any relevant malalignment in complex femur-shaft fractures whilst exposing patients to an acceptable amount of additional procedure sequences. Malalignment can be avoided by using a navigation system in the operative treatment of femoral-shaft fractures and may be integrated into clinical routine in specialised centres.


Foot & Ankle International | 2010

Arthroscopic-Controlled Navigation for Retrograde Drilling of Osteochondral Lesions of the Talus

Florian Gras; Ivan Marintschev; Matthias Müller; Kajetan Klos; Robert Lindner; Thomas Mückley; Gunther O. Hofmann

Background: Retrograde drilling of symptomatic osteochondral lesions (OCL) is usually controlled by fluoroscopy. Due to the limited visualization of the OCLs in the acquired images and the narrow access to the talar dome, this approach can be demanding. Several navigation procedures have been reported (2D- or 3D- fluoroscopy or intraoperative CT-based) to increase the accuracy and reduce the radiation exposure. We developed a new arthroscopic-controlled navigation procedure which is free of radiation exposure and free of a reference base rigidly fixed to the bone. 17 We hypothesized that this procedure (Fluoro-Free) is at least as precise as the standard 2D-Fluoro navigation (2D-Fluoro). Furthermore, our first clinical experiences are described and discussed. Material and Methods: Sixteen drillings per group (standard 2D-Fluoro vs. Fluoro-Free) were performed in artificial sawbones. Times for the different steps of each drilling procedure were recorded and the precision evaluated by measuring the deviation and depth of drilling. Results: The accuracy of the Fluoro-Free navigation was as precise as the standard 2D-Fluoro based navigation (axis deviation of drill tip to the target point: 1.07 ± 0.11 versus 1.14 ± 0.15 mm). Due to the simplified workflow without radiation exposure and fixation of a reference base, the Fluoro-Free procedure was significantly faster (mean procedure time per drilling: 23.7 ± 11.6 versus 165 ± 9 seconds) and easy to use. Its clinical usefulness was demonstrated during three retrograde drillings of a talar OCL in a 16-year-old patient. Conclusion: The Fluoro-Free navigation procedure is a simplified approach for retrograde drilling of OCL in the talus under arthroscopic control without radiation exposure and without the need for fixation of a dynamic reference base to the bone. Level of Evidence: V, Expert Opinion


Foot and Ankle Surgery | 2013

Modified Lapidus arthrodesis with plantar plate and compression screw for treatment of hallux valgus with hypermobility of the first ray: A preliminary report

Kajetan Klos; Christoph H. Wilde; Antje Lange; Andreas Wagner; Florian Gras; Hristo Skulev; Thomas Mückley; Paul Simons

BACKGROUND TMT-1 arthrodesis is an established method in hallux valgus surgery, but it is technically demanding and typically calls for a period of postoperative immobilization. METHODS In this cohort study, initial experience with a plantar plate is described. 58 patients (59 arthrodesis) were included. RESULTS The mean duration of protected full weight bearing was 7 weeks. 94.12% patients were satisfied with the results, bony union was achieved in 98.31%. The Foot Function Index improved by 33 to a mean of 8 (p<.001). The postoperative Mayo Clinic Forefoot Score was excellent in 47.04 and good in 47.04%. The mean hallux valgus angle improved by 24.4-13.2° (p<.001). The mean first intermetatarsal angle improved by 11.2-5.2° (p<.001). CONCLUSION Initial experience with this form of fixation appears to provide suitable stability, allow early-protected weight bearing, with an acceptable level of complications.


Journal of Trauma-injury Infection and Critical Care | 2012

Screw- versus plate-fixation strength of acetabular anterior column fractures: a biomechanical study.

Florian Gras; Ivan Marintschev; Christoph E. Schwarz; Gunther O. Hofmann; Tim Pohlemann; Ulf Culemann

BACKGROUND The standard for operative treatment of acetabular fractures is open reduction and plate fixation. Recently, screw fixation-only methods through less invasive approaches are reported, but biomechanical data are missing. Questions posed in this study are (1) is the static fixation strength of different screw types equivalent to the standard plate fixation for anterior column fractures of the acetabulum? and (2) does the placement of an additional screw in the infra-acetabular corridor increase the fixation strength independent of the used implant? METHODS Three groups of different screws (group II, titanium; group III, stainless steel; and group IV, biodegradable Poly-l-Lactid) were compared with the standard plate fixation (group I) in Synbone pelves with custom-made anterior column fractures. Six pelvises per group were axial loaded with six cycles of 800 N, twice with and without an additional placed infra-acetabular screw. RESULTS The fixation strength of titanium screws was equivalent to the standard plate fixation. The stainless steel and Poly-l-Lactid screw fixation strengths were equivalent to each other but inferior to the aforementioned. The additional placement of an infra-acetabular screw significantly increased the fracture fixation strength, independent of the used implant. CONCLUSION Screw fixation is a promising alternative approach for the stabilization of noncomminuted acetabular fractures of the anterior column with equivalent fixation strength to the standard plate fixation. The additional placement of an infra-acetabular screw significantly increases the fracture fixation independent of the used implant and should be considered for acetabular fractures with separation of both columns. LEVEL OF EVIDENCE Therapeutic study, level IV.


Injury-international Journal of The Care of The Injured | 2013

Volar versus dorsal latest-generation variable-angle locking plates for the fixation of AO type 23C 2.1 distal radius fractures: A biomechanical study in cadavers

Sascha Rausch; Olaf Schlonski; Kajetan Klos; Florian Gras; Boyko Gueorguiev; Gunther O. Hofmann; Thomas Mückley

INTRODUCTION Anatomicaly preformed variable-angle locking plates are technologically mature and appear to be optimal for the fixation of distal radius fractures. However, there is still much argument about whether volar plating is equivalent to dorsal (buttressing) plating, especially in the management of intra-articular extension fractures. This biomechanical study was performed to determine, in a simple intra-articular fracture model, whether dorsal or volar plate constructs would be more stable. MATERIALS AND METHODS Six pairs of fresh frozen radii were examined with dual-energy absorptiometry (DXA) to determine their bone mineral density (BMD). An AO type 23 C2.1 fracture was created. Volar fixation was with a 2.4mm Variable-Angle LCP Two-Column Volar Distal Radius Plate; dorsal fixation was with two orthogonal 2.4 mm Variable-Angle LCP Dorsal Distal Radius Plates (both devices: Synthes, Oberdorf, Switzerland). Biomechanical testing used a proven protocol involving static tests of stiffness, and a cyclic test to obtain range of motion (ROM), maximum deformation, and subsidence data. RESULTS None of the constructs failed during biomechanical testing. The two groups (volar and dorsal plating, respectively) did not differ significantly in terms of initial (pre-cyclic-testing) and final (post-cyclic-testing) stiffness. Equally, there was no significant difference between the subsidence values in the two groups. The post-cyclic-testing ROM was significantly greater in the dorsal-plate group as compared with the volar-plate group. The volar constructs showed a significant decrease in the ROM between pre- and post-cyclic testing. CONCLUSION Biomechanically, volar plating with a modern variable-angle locking plate is equivalent to dorsal plating with two modern variable-angle locking plates.

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Ivan Marintschev

Martin Luther University of Halle-Wittenberg

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