Francis Ejobi

Risk factors, perceptions and practices associated with Taenia solium cysticercosis and its control in the smallholder pig production systems in Uganda: a cross-sectional survey.

BackgroundPrevalence studies report Taenia solium cysticercosis in pig and human populations in Uganda. However, the factors influencing occurrence in smallholder pig production systems are not well documented and little is known about farmers’ perceptions of T. solium cysticercosis or farmer practices that could reduce transmission.MethodsTo determine the risk factors, perceptions and practices regarding T. solium cysticercosis, a household survey using a semi-structured questionnaire was conducted in 1185 households in the rural and urban pig production systems in Masaka, Mukono and Kamuli Districts. Logistic regression was used to measure associations of risk factors with infection. Performance scores were calculated to summarise perceptions and practices of farmers regarding taeniosis, human cysticercosis and porcine cysticercosis as well as farmer behavior related to control or breaking transmission.ResultsPig breed type, farmers’ knowledge about transmission, sources of water used, and pig keeping homes where family members were unable to use the latrine were all significantly associated with T. solium cysticercosis in pigs. Performance scores indicated that farmers were more aware of taeniosis (63.0%; 95% Confidence Interval 60.0-65.8) than human or porcine cysticercosis; only three farmers (0.3%, 95% CI = 0.1–0.8) had knowledge on all three conditions. More farmers reported that they dewormed pigs (94.1%) than reported deworming themselves and their family members (62.0%). Albendazole was the most commonly used drug for deworming both pigs and humans (85.0 and 81.5% respectively). Just over half (54.6%) of the farmers interviewed had clean water near the latrines for washing hands. Of these, only 41.9% used water with soap to wash hands after latrine use.ConclusionFactors that significantly influenced occurrence of T. solium cysticercosis in pigs were identified. Farmers had some knowledge about the disease but did not link taeniosis, human cysticercosis, and porcine cysticercosis. Therefore, there is need to employ strategies that raise awareness and interrupt transmission.

Africa ' s unfolding diet transformation: implications for agrifood system employment

Purpose - – The purpose of this paper is to understand how the unfolding diet transformation in East and Southern Africa is likely to influence the evolution of employment within its agrifood system (AFS) and between that system and the rest of the economy. To briefly consider implications for education and skill acquisition. Design/methodology/approach - – The authors link changing diets to employment structure. The authors then use alternative projections of diet change over 15- and 30-year intervals to develop scenarios on changes in employment structure. Findings - – As long as incomes in ESA continue to rise at levels near those of the past decade, the transformation of their economies is likely to advance dramatically. Key features will be: sharp decline in the share of the workforce engaged in farming even as absolute numbers rise modestly, sharp increase in the share engaged in non-farm segments of the AFS, and an even sharper increase in the share engaged outside the AFS. Within the AFS, food preparation away from home is likely to grow most rapidly, followed by food manufacturing, and finally by marketing, transport, and other AFS services. Resource booms in Mozambique and (potentially) Tanzania are the main factor that may change this pattern. Research limitations/implications - – Clarifying policy implications requires renewed research given the rapid changes in Africa over the past 15 years. Originality/value - – This is the first paper to explicitly link changing diets to changing employment within the AFS.

Sero-prevalence of Taenia spp. cysticercosis in rural and urban smallholder pig production settings in Uganda.

The pork tapeworm, Taenia solium, is prevalent in Uganda although the prevalence has not been determined in all areas of the country. A cross-sectional study, to determine the sero-prevalence of the parasite in pigs kept under rural and urban production settings, was carried out in three Ugandan districts, Masaka, Mukono and Kamuli. Serum samples from 1185 pigs were tested for the presence of T. solium cysticercosis antigen using the HP10 antigen-ELISA (Ag-ELISA) and the ApDia Ag-ELISA assays. Using parallel interpretation of the two tests showed lower levels of observed prevalence of T. solium in rural production settings (10.8%) compared to urban (17.1%). Additionally, Maximum Likelihood Estimation for evaluating assays in the absence of a gold standard, using TAGS on the R platform, estimated the true sero-prevalence to be lower in rural production setting, 0.0% [0.0-3.2%; 95% confidence interval (CI)] than in urban production setting, 12.3% (4.2-77.5% CI). When the sensitivity/specificity (Se/Sp) of the assays were estimated, assuming conditional independence of the tests, HP10 Ag-ELISA was more sensitive and specific [(Se=53.9%; 10.1-100% CI), (Sp=97.0%; 95.9-100% CI)] than the ApDia assay [(Se=20.2%; 1.5-47.7% CI), (Sp=92.2%; 90.5-93.9% CI)]. Subject to parasitological verification, these results indicate there may be a need to implement appropriate control measures for T. solium in the study areas.

Assessment of the economic viability of goat management systems in Goma Sub County and Mukono Town Council in Mukono District, Uganda

This study sought to assess the profitability of the goat enterprises under different management systems. The research covered two selected sub-counties of Mukono District (Goma and Mukono Town Council). A total of 888 goats from 129 herds/farms were studied. Descriptive statistical and gross margins analyses were performed. The management system of goats in the two sub-counties was mainly by tethering. Most of the goats kept were adult female goats. Most farmers had small herds and did not keep records. Male goats were more valued on average among the crossbred goats. In the exotic types, the adult female goats were valued on average. Local goats fetch low prices. With respect to gross margins, that free range had incurred more losses, while tethering made most profits followed by zero grazing and zero grazing combined with tethering, respectively, without considering the non-monetary aspects. Farmers using the tethering management system, encountered most of the problems of lack of pastures and veterinary services. The farmers required assistance from different donors, through provision of hybrid goats and improvement of veterinary services. The management system for goat keeping in the study area was poor, especially among local breed goat farmers who use tethering management system, though it had high gross margin. There is a need to educate farmers on proper goat husbandry and provision of some farm inputs.

Risk factors associated with cystic echinococcosis in humans in selected pastoral and agro-pastoral areas of Uganda

It was to determine the risk factors responsible of occurrence of cystic echinococcosis (CE) of humans in the pastoral and agro-pastoral (PAP) in Uganda.

A systematic review: the current status of carbapenem resistance in East Africa

ObjectiveIn this systematic review, we present the molecular epidemiology and knowledge gaps of the carbapenem resistance in East Africa as well as the future probable research interventions that can be used to address the emergence of carbapenem resistance in the region.ResultsThe 17 articles which presented concrete information about the prevalence of carbapenem resistance in East Africa were reviewed. Tanzania exhibited the highest level of carbapenem resistance at 35% while DRC had the lowest level at 0.96%. Uganda was the only country with studies documenting CR obtained amongst hospital environment isolates with incidence ranging from 21% in Pseudomonas aeruginosa to 55% in Acinetobacter baumannii. Carbapenem resistance was more exhibited in A. baumannii (23%), followed by P. aeruginosa (17%), Klebsiella pneumoniae (15%), Proteus mirabilis (14%) and Escherichia coli (12%) mainly isolated from respiratory tract, blood, urine and wound/pus. The regional genetic determinants of carbapenem resistance detected were blaIMP, blaVIM-1 blaSPM-l, blaNDM-1, blaOXA-23 blaOXA-24, blaOXA-58 and blaKPC.

Sociocultural factors associated with fish consumption in Lake Albert fishing community: Guidelines for lead and mercury

Abstract Fish consumption in subsistence fishing community is a life style associated with lead and mercury uptake for humans. Fish consumption is influenced by sociocultural factors, exposure and health risks. Unfortunately, no sociocultural study in the Lake Albert fishing community in light of lead and mercury exists. A cross-sectional sociocultural study was carried out between March and June 2015. A total of 270 household heads in four landing sites in Hoima district completed structured questionnaires and data analyzed using SPSS version 20. The majority of the households (74.8%) had primary education or below, 51.1% drank unboiled water, and 30% perceived lake water safe for drinking. Children under five ate soup (15%) and middle piece of the fish (29%). The Poisson general linear model predicting weekly fish consumption amounts against sociocultural factors showed that household size (p = 0.047), male child presence (p = 0.007), methods of preparation i.e. salting (p < 0.0001), fish parts consumed by adults (p < 0.0001), fish preference (p < 0.0001), awareness about the beach management unit (p < 0.0001), and income from charcoal selling (p < 0.0001) were positive predictors. The negative predictors of weekly fish consumption amounts were awareness about fish consumption benefits (p < 0.0001), eating young fish (p = 0.002), donor agency presence (p < 0.0001), and frying as the method of fish preparation (p = 0.002). In conclusion, knowledge of the sociocultural factors associated with fish consumption determines the amounts and frequency of the predominant fish eaten. Therefore, to establish and adopt fish consumption guidelines for lead and mercury in the Lake Albert, the sociocultural factors should be integrated in the message disseminated.