Francis J. Gregory

Effect of mixtures of atabrine and antibacterial agents on the emergence of resistant strains of Mycobacterium tuberculosis.

THERE have been numerous descriptions of the successful use of mixtures of antibiotics and atabrine in preventing the emergence of resistant strains of Staphylococcus aureus and Escherichia coli1–4. When a sensitive strain of these organisms was subcultured in an antibiotic, however, the mixture of antibiotic and atabrine was no longer effective in eliminating resistance.