Francisco Antônio Félix Xavier Júnior

Crotalus durissus venom: biological effects and relevant applications. A Review

Snakes have an important biological role in the ecological chain, as well as in scientific researches performed with the venoms produced by them, since the enzyme-protein fractions these substances possess have been studied as pharmacological tools for the discovery of new therapies. Snakes of the genus Crotalus have gained significant relevance in the scientific field, since the venom produced by these reptiles has been the target of researchers in a few decades, due to the composition and the effects that these substances can produce. In Brazil, a single species represents the genus, which is Crotalus durissus. This review demonstrates that even with the advancement in scientific research on the composition, role and application of the venom produced by the subspecies of Crotalus durissus snake, it is necessary to further study their fractions and their action potential, which also demonstrates the how rich are these active components in different fields of biomedicine.

Clinical and laboratory diagnostic approach of intratbuluar sertolioma in a cryptorchid dog

Sertolioma is a common type of primary unilateral or bilateral testicular cancer, generally without signs that indicate the possibility of metastasis. This paper describes the clinical and laboratory diagnostic approach of a cryptorchid dog with sertolioma. The object of study was a male Pinscher dog, which reported the presence of a nodule in the inguinal region by its owner. Upon the nodule palpation during the physical examination, it was found the presence of edema and increased volume with firm consistency, but without fibrous features. Complete blood count, serum biochemical tests, ECG and echocardiogram, and fine-needle aspiration cytology were requested. Among other findings, cytology showed changes suggesting sertolioma: Numerous round and polygonal cells of large cytoplasm,

Gastrotomy in dog for removal of foreign body in caudal esophagus. Case report

Foreign bodies are digestible or not objects that can cause esophageal obstruction. Once located, the clinician must decide whether to observe its passage or perform the removal, being immediate intervention the most recommended. With that, we aimed to report a case of foreign body in the caudal esophagus of a canine, female, 8 years, with history of regurgitation and hyporexia. Based on anamnesis and physical examination findings, radiographs were performed in the laterolateral and ventrodorsal incidences, which showed the presence of radiopaque image (bone), confirming the presence of esophageal foreign body. In addition, ultrasound was requested and tests of serum biochemistry, all with no changes. As conduct, gastrostomy was performed to remove the bone and desobstruction.

Feline hypertrophic cardiomyopathy relevant aspects

Hypertrophic cardiomyopathy is a clinically heterogeneous disorder characterized by mild to severe thickening of left ventricular chamber associated with diastolic dysfunction. The main clinical signs are typically respiratory abnormalities secondary to pulmonary edema and/or pleural effusion; mild to severe acute heart failure; and paraparesis/paraplegia caused by arterial thromboembolism. The diagnosis should be based on a positive family history and the causes that cause secondary hypertrophy should be discarded. Echocardiography is currently the gold standard for the diagnosis of this pathology. It is the most common heart disease in adult cats; therefore, it is necessary knowledge of the condition in order to perform an effective clinical management, improving prognosis and quality of life of the animal.