Francisco Miguel Camacho Martínez

Baboon syndrome in childhood: easy to avoid, easy to diagnose, but the problem continues.

Abstract:  Baboon syndrome was first described as a particular type of systemic contact dermatitis, characterized by an exanthem with involvement of the buttocks and flexures. In children, it is an important entity to take into account for the differential diagnosis of viral exanthem. A large number of allergens have been implicated, although inhalation of mercury vapor is a common trigger. We present the findings in 14 patients younger than 14 years with baboon syndrome. We also look at the frequency in children and the most common causes and triggers in our area.

Perifollicular erythema as a trichoscopy sign of progression in frontal fibrosing alopecia

Introduction: Frontal fibrosing alopecia (FFA) in an entity characterized by the recession of the frontotemporal hairline (FTHL) with alopecic scarring change. In recent years there are numerous articles discussing the usefulness of dermoscopy for the clinical diagnosis of different types of scarring alopecia. Materials and Methods: We value 79 patients diagnosed with FFA, evaluating some trichoscopical findings described as typical for FFA: Absence of follicular opening, follicular hyperkeratosis, follicular plugs and erythema. Results: In a population of 79 women, 100% showed no follicular opening, 72.1% follicular hyperkeratosis, 66.3% perifollicular erythema and 44.8% follicular plugs. Thus, 100% of patients had at least one of the dermoscopic elements described as suggestive of FFA, 53% two of them, 45% three and 27%, all those elements. Perifollicular erythema was present in 95% of cases in which the disease was active. Conclusions: We consider that the presence of perifollicular erythema will be a direct marker of FFA activity.

Generalized pustulosis and severe tubulointerstitial nephropathy as manifestations of carbamazepine hypersensitivity syndrome.

growth factor and its receptor mRNA in angiosarcoma. No statistical diVerences were found in serum VEGF Lab Invest 1995; 73: 859–863. levels between the other angiosarcoma patients (cases 2. Masood R, Cai J, Zheng T, Smith L, Naidu Y, Gill PS. 3–11) in whom the p53 gene point mutation was not Vascular endothelial growth factor/vascular permeability detected; these patients include those without metastasis factor is an autocrine growth factor for AIDS-associated (153 ± 70 pgml O 1 , range 65–223, n = 4), those with Kaposi’s sarcoma. Proc Natl Acad Sci USA 1997; 94: metastasis to parotid lymph nodes (166 ± 70 pgml O 1 , 979–984. 3. Naka N, Tomita Y, Nakanishi H, Araki N, Hongyo T, range 62–244, n =6), and those with remote metastasis Ochi T, et al. Mutation of p53 tumor-suppressor gene in (119 ± 101 pgml O 1 , range 7–269, n =7) (Fig. 1). angiosarcoma. Int J Cancer 1997; 71: 952–955. Because of serious heart failure, the patient who had 4. Masuzawa M, Fujimura T, Hamada Y, Fujita Y, Hara H, detectable p53 gene point mutation (case 1) was treated Nishiyama S, et al. Establishment of a human hemangiosarwith local radiation therapy alone. The other patients coma cell line (ISO-HAS). Int J Cancer 1999; 81: 305–308. were treated with surgery, radiation therapy, local or 5. Amo Y, Masuzawa M, Hamada Y, Takasu H, Fujimura T, Katsuoka K, et al. Serum levels of vascular endothelial systemic administration of recombinant interleukin-2 growth factor in a hemangiosarcoma patient with a new(IL-2), and immunotherapy using IL-2 and IL-2typed p53 gene point mutation. Br J Dermatol 2000; 143: activated lymphocytes. The eVect of these treatments 1118–1119. may have contributed to the serum VEGF levels. 6. Amo Y, MasuzawaM, Hamada Y, Katsuoka K. Expression Therefore, serum VEGF levels may not be correlated of vascular endothelial growth factor in a human hemanwith clinical course in most cases of angiosarcomas giosarcoma cell line (ISO-HAS). Arch Dermatol Res 2001; without p53 gene mutation. 293: 296–301. 7. Hollstein M, Sidransky D, Vogelstein B, Harris SR. p53 mutations in human cancers. Science 1991; 253: 49–53. REFERENCES

Superficial Acral Fibromyxoma involving the nail's apparatus. Case report and literature review

Superficial Acral Fibromyxoma is a rare tumor of soft tissues. It is a relatively new entity described in 2001 by Fetsch et al. It probably represents a fibrohistiocytic tumor with less than 170 described cases. We bring a new case of SAF on the 5th toe of the right foot, in a 43-year-old woman. After surgical excision with safety margins which included the nail apparatus, it has not recurred (22 months of follow up). We carried out a review of the location of all SAF published up to the present day.

Dermatitis Artefacta in Childhood: A Retrospective Analysis of 44 Patients, 1976–2006

Dermatitis artefacta (DA) consists of self‐inflicted skin lesions that the patient denies having produced.

O to Z flaps in facial reconstructions.

Local flaps are the standard procedure to reconstruct facial defects. As it occurs in any surgical procedure, the incision should be planned so that scars are located in the minimum skin tension lines. We report two cases of O to Z flaps in the supra and infraciliary regions. One of them is a hatchet flap.

Lupus vulgaris diagnosed 62 years after onset

ejd.2011.1501 Auteur(s) : Jose Neila drneils@hotmail.com, Lara Ferrandiz, David Moreno-Ramirez, Francisco Camacho Martinez Department of Dermatology, Virgen Macarena University Hospital, Av/ Dr. Fedriani s/n, 41009 Seville, Spain We are witnessing a rise in tuberculosis incidence in developed countries [1]. The HIV epidemic, population migration from high endemic areas, development of antibiotic-resistant strains of Mycobacterium tuberculosis and wider use of immunosuppressive therapies have been [...]

Dermatitis de contacto en la adolescencia

La Organizacion Mundial de la Salud define la adolescencia como el periodo comprendido entre los 10 y los 19 anos de edad, durante el cual se producen cambios fisicos, psicologicos y conductuales. En esos anos, los adolescentes adquieren nuevos habitos que pueden favorecer el contacto con diversos alergenos que antes estaban restringidos a adultos, como, por ejemplo, cosmeticos, piercing y tatuajes1. Ademas de estos nuevos habitos, los adolescentes que padecieron alguna dermatosis durante su infancia, como dermatitis atopica, son mas susceptibles a posibles sensibilizaciones, facilitadas por haber tenido alterada la barrera cutanea o haber estado en contacto con tratamientos topicos, que son potenciales alergenos2. La informacion de que disponemos acerca de la incidencia y de la prevalencia de dermatitis alergica de contacto (DAC) entre los adolescentes es muy escasa3. En la decada de los noventa, la mayoria de las publicaciones fueron series de casos de ninos y adolescentes con DAC o estudios en ninos y adolescentes con sospecha de DAC. Existen muy pocos estudios en que se haya realizado pruebas epicutaneas a poblaciones de adolescentes no seleccionadas por su enfermedad4-6 y que valoren en ellos la relevancia de las positividades de estos tests, para asi poder hacer una estimacion real de la prevalencia de DAC en este grupo etario. Tampoco existen estudios de seguimiento adecuado que valoren la incidencia3. Tanto la dermatitis irritativa como la dermatitis alergica de contacto ocurren durante la infancia y la adolescencia. En general los alergenos de contacto mas comunes en adolescentes son los mismos que en los adultos, aunque hay diferencias de un pais a otro debido a la distinta exposicion a los alergenos7.