Frank A. Vicini

Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast

Ductal carcinoma in situ (DCIS) is detected most commonly on routine screening mammography in the asymptomatic patient, and has a long natural history. The objective of the current study was to determine the long‐term outcome after breast‐conservation surgery followed by definitive breast irradiation for women with mammographically detected DCIS of the breast.

Long-term cosmetic results and toxicity after accelerated partial-breast irradiation : A method of radiation delivery by interstitial brachytherapy for the treatment of early-stage breast carcinoma

The objective of this study was to assess the cosmesis and toxicities in patients with early‐stage breast carcinoma who received treatment with accelerated partial breast irradiation (APBI) using interstitial brachytherapy.

First Analysis of Patient Demographics, Technical Reproducibility, Cosmesis, and Early Toxicity Results of the American Society of Breast Surgeons MammoSite Breast Brachytherapy Registry Trial

Eighty‐seven institutions participated in a Registry Trial that was designed to collect data on the clinical use of the MammoSite™ breast brachytherapy catheter for delivering breast irradiation. Patient demographics, technical reproducibility, cosmesis, and early toxicity were evaluated.

Does local recurrence affect the rate of distant metastases and survival in patients with early‐stage breast carcinoma treated with breast‐conserving therapy?

The purpose of the current analysis was to evaluate the impact of local recurrence (LR) on the development of distant metastases (DM), overall survival (OS), and cause specific survival (CSS) in patients with early‐stage breast carcinoma who underwent conservative surgery (CS) and received postoperative radiotherapy (RT).

The conservative management of Paget's disease of the breast with radiotherapy

The purpose of this study was to evaluate the feasibility of breast‐conserving therapy involving limited surgery and definitive radiotherapy as a treatment for Pagets disease, and to determine the disease free and overall survival associated with this approach.

Clinicopathologic implications of E-cadherin reactivity in patients with lobular carcinoma in situ of the breast

The current study addressed two questions pertaining to lobular carcinoma in situ (LCIS) of the breast. First, does the risk of a subsequent carcinoma decrease over time after an LCIS biopsy and second, what is the clinical significance of E‐cadherin‐reactive LCIS?

A comparison of external beam radiation therapy versus radical prostatectomy for patients with low risk prostate carcinoma diagnosed, staged, and treated at a single institution

The authors retrospectively reviewed their institutions long term experience treating a group of comparably staged low risk prostate carcinoma patients with either radical prostatectomy or external beam radiation therapy (RT) to determine whether the method of treatment resulted in significant differences in biochemical control and/or survival.

An interinstitutional and interspecialty comparison of treatment outcome data for patients with prostate carcinoma based on predefined prognostic categories and minimum follow-up

The optimal management of patients with clinically localized prostate carcinoma remains undefined due in part to the absence of well‐designed, prospective, randomized trials. The current study was conducted to compare and contrast outcomes with different forms of therapy for patients with prostate carcinoma who were treated at several institutions using predefined prognostic categories.

Treatment outcome with radiation therapy after breast augmentation or reconstruction in patients with primary breast carcinoma

Analyses were performed to determine local control and cosmetic outcome of breast carcinoma patients with prosthetically augmented or reconstructed breasts who had received radiation therapy (RT).

Factors associated with local recurrence of mammographically detected ductal carcinoma in situ in patients given breast-conserving therapy

The authors reviewed their institutions experience treating patients with mammographically detected ductal carcinoma in situ (DCIS) of the breast with breast‐conserving therapy (BCT) to determine 10‐year rates of local control and survival and to identify factors associated with local recurrence.