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Frank F. Ebetino

Norwich Pharma Services

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Publication

Featured researches published by Frank F. Ebetino.

Archives of Biochemistry and Biophysics | 1966

The aerobic degradation of 1-(5-nitrofurfurylideneamino)-2-imidazolidinone (NF-246) by Escherichia coli

John J. Gavin; Frank F. Ebetino; R. Freedman; W.E. Waterbury

Abstract The bacterial degradation of 1-(5-nitrofurfurylideneamino)-2-imidazolidinone (NF-246) has been studied by using Escherichia coli as the test organism. It has been determined that the aminofuran analogue, 1-(5-aminofurfurylideneamino)-2-imidazolidinone (F-305), is not an intermediate in this process and that the major product (60–70% conversion) is the open-chain nitrile, 3-(4-cyano-2-oxobutylideneamino)-2-imidazolidinone (U-813). A metabolic pathway for this conversion is postulated.

Journal of Medicinal Chemistry | 1971

Synthesis and hypotensive properties of new 4-aminoquinolines.

George C. Wright; Edward J. Watson; Frank F. Ebetino; Guy Lougheed; Benjamin F. Stevenson; Alexander Winterstein; Robert K. Bickerton; Robert P. Halliday; Donald T. Pals

Journal of Medicinal Chemistry | 1962

REDUCTION OF NITROFURANS. I. AMINOFURANS.

Frank F. Ebetino; James J. Carroll; Gabriel Gever

Journal of Medicinal Chemistry | 1966

Anticoccidial Activity in a Series of Alkyl 6,7-Dialkoxy-4-hydroxy-3-quinolinecarboxylates

Claude F. Spencer; Alan T. Engle; Chia-Nien Yu; Raymond C. Finch; Edward J. Watson; Frank F. Ebetino; Cornell A. Johnson

Journal of Heterocyclic Chemistry | 1966

A new synthesis of furo[2,3‐b]pyridine derivatives

Harry R. Snyder; Frank F. Ebetino

Journal of the American Chemical Society | 1955

Chemotherapeutic Nitrofurans. I. Some Derivatives of 3-Amino-2-oxazolidone1

Gabriel Gever; Charles O'keefe; Gordon Drake; Frank F. Ebetino; Julian G. Michels; Kenyon J. Hayes

Journal of Organic Chemistry | 1962

Chemotherapeutic Nitrofurans. VII.1 The Formation of 5-Nitrofurfurylidene Derivatives of Some Aminoguanidines, Aminotriazoles, and Related Compounds

Frank F. Ebetino; Gabriel Gever

Journal of Organic Chemistry | 1963

An Extention of the Gomberg—Bachmann Pinacol Synthesis

Frank F. Ebetino; E. D. Amstutz

Journal of Medicinal Chemistry | 1970

1-substituted-3-(5-nitrofurfurylidene-amino)-2-imidazolidinones

Harry R. Snyder; Frank F. Ebetino; A. J. Siedler; Jon. Andersen

Journal of the American Chemical Society | 1955

Chemotherapeutic Nitrofurans. II.1 The Formation and Some Reactions of Derivatives of 3-Amino-2-iminoöxazolidine

Kenyon J. Hayes; Frank F. Ebetino; Gabriel Gever

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Kenyon J. Hayes

Norwich University

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Gordon Drake

Norwich University

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Harry R. Snyder

Norwich University

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Julian G. Michels

Norwich University

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Robert K. Bickerton

University of Pittsburgh

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Robert P. Halliday

University of Pittsburgh

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