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Dive into the research topics where Frank J. Lexa is active.

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Featured researches published by Frank J. Lexa.


Journal of Magnetic Resonance Imaging | 2000

Magnetization transfer imaging of traumatic brain injury

Linda J. Bagley; Joseph C. McGowan; Robert I. Grossman; Grant Sinson; Mark Kotapka; Frank J. Lexa; Jesse A. Berlin; Tracy K. McIntosh

Magnetization transfer imaging (MTI) has been shown to be sensitive for the detection of white matter abnormalities in entities such as multiple sclerosis, progressive multifocal leukencephalopathy, and wallerian degeneration. Our hypothesis was that MTI would detect traumatic white matter abnormalities (TWMA) and provide information additional to that obtainable with routine spin‐ and gradient‐echo imaging. We hypothesized that the presence of TWMA defined by MTI would correlate with outcome following TBI. Twenty‐eight victims of head trauma and 15 normal controls underwent magnetic resonance imaging including MTI. Magnetization transfer ratios (MTR) were calculated for areas of shearing injury and for normal‐appearing white matter (NAWM) in locations frequently subject to diffuse axonal injury. Abnormal MTRs were detected in NAWM in eight patients. All eight had persistent neurologic deficits, including cognitive deficits, aphasia, and extremity weakness. Seven of the 28 patients had no abnormal findings on neurologic exam at discharge, transfer, or follow‐up. None of these patients had an abnormal MTR in NAWM. In the remaining 13 patients, who had persistent neurologic deficits, no regions of abnormal MTR were detected in NAWM. MTI is a sensitive method for the detection of TWMA. Detection of abnormal MTR in NAWM that is prone to axonal injury may predict a poor patient outcome. The presence of normal MTR in NAWM in these areas does not necessarily confer a good outcome, however. J. Magn. Reson. Imaging 2000;11:1–8.


Journal of The American College of Radiology | 2011

ACR White Paper: Strategies for Radiologists in the Era of Health Care Reform and Accountable Care Organizations: A Report From the ACR Future Trends Committee

Bibb Allen; David C. Levin; Michael Brant-Zawadzki; Frank J. Lexa; Richard Duszak

Accountable care organizations have received considerable attention as a component of health care reform and have been specifically addressed in recent national legislation and demonstration projects by CMS. The role or roles of radiologists in such organizations are currently unclear, as are changes to the ways in which imaging services will be delivered. The authors review concepts fundamental to accountable care organizations and describe roles for radiologists that may facilitate their success in such health care delivery systems.


Journal of Vascular Surgery | 1997

Magnetic resonance angiography of the aortic arch

Jeffrey P. Carpenter; George A. Holland; Michael A. Golden; Clyde F. Barker; Frank J. Lexa; Maryellyn Gilfeather; Mitchell D. Schnall

Duplex ultrasound and magnetic resonance angiographic (MRA) studies are the principal noninvasive methods for evaluation of extracranial occlusive disease in patients at risk for stroke, but each has limited ability to diagnose aortic arch and arch vessel disease. Recent favorable reports of the nonnephrotoxic contrast agent Gadolinium (Gd) being used to enhance MRA images of the abdominal aorta prompted us to examine its utility for the aortic arch vessels. Prospectively, 28 patients with suspected carotid or arch vessel disease were imaged by contrast arteriographic examination and MRA + Gd of the aortic arch within 30 days of each other. One (for contrast arteriograms) or two (for MRA) blinded readers measured stenoses with the contrast arteriograms as the standard. A total of 196 arch vessels containing 58 stenoses and four occlusions (by arteriogram) were examined with each method. Interobserver agreement for interpretation of MRA studies was substantial (kappa = 0.68). MRA detected all anatomic anomalies (e.g., bovine arch). The correlation of MRA with arteriographic scans for arch vessel stenoses > 50% was sensitivity, 73% (readers 1 and 2); specificity, 98% (reader 1), 89% (reader 2); positive predictive value, 73% (reader 1), 89% (reader 2); negative predictive value, 98% (readers 1 and 2); accuracy, 97% (reader 1), 98% (reader 2). MRA + Gd is an accurate new noninvasive imaging method for detection of significant aortic arch disease. In its current state of development, however, it cannot obviate the need for contrast arteriographic examination.


Journal of Computer Assisted Tomography | 1994

MRI of carotid angiopathy after therapeutic radiation.

Tae Sub Chung; David M. Yousem; Frank J. Lexa; Deborah A. Markiewicz

Objective Our goal was to assess whether significant secondary atherosclerotic changes from radiation can be detected on SE MR of the neck. Materials and Methods Pre- and postradiation MR scans of 16 patients with head and neck malignancies were studied randomly, independently, and blindly by two readers to determine the frequency of narrowing of the carotid arterial lumen and obliteration of the carotid space within the carotid sheath. Results Interval narrowing of either the common, internal, or external carotid artery lumen was seen in 108 of 192 (56%) of vessels evaluated on postradiation MR scans compared with preradiation studies. The differences in the grades of vessel luminal diameter were statistically significant (p < 0.05 for one reader and p < 0.0001 for the other reader). Among the 16 patients, 3 patients had vessels with a critical degree of stenosis, newly appearing on postradiation scans. Seven of 16 patients had diffuse obliteration of the planes within the carotid space. Conclusion The incidence of accelerated atherosclerosis from therapeutic radiation may be greater than expected in nonirradiated patients. Magnetic resonance scans are an effective, noninvasive method for this type of follow-up.


Journal of The American College of Radiology | 2011

A Radiologist's Primer on Accountable Care Organizations

Jonathan Breslau; Frank J. Lexa

The Patient Protection and Affordable Care Act that was signed into law in March 2010 included specific language codifying a new health care entity, the accountable care organization. The accountable care organization model is put forward as a way to increase value in health care, that is, improving outcomes as efficiently as possible. It is not known whether this concept can be applied successfully beyond the carefully selected examples where it already functions. Three general principles figure prominently in known successful models: the provision of efficient primary care, shared savings, and IT infrastructure. The authors discuss these concepts, ongoing uncertainties, and how radiologists may fit into an accountable care organization.


Journal of The American College of Radiology | 2009

The Architecture of Smart Surveys: Core Issues in Why and How to Collect Patient and Referring Physician Satisfaction Data

Frank J. Lexa; Jonathan W. Berlin

Radiology practices are facing challenges on many fronts. As the field becomes more competitive, leaders must pay more attention to the quality of the service that groups provide to their customers. This need is also being driven by higher expectations from customers, particularly patients, who will likely act much more like consumers in the 21st century. For practices to succeed in providing exemplary service, they must pay attention to the voices of their key customer groups. It is dismaying to see practices that are struggling or even dissolving over issues created by poor service. As much as we are experts in imaging, we are unlikely to be able to provide superlative service by reading books, talking among ourselves, or hiring consultants. Rather, we must do what should be obvious, which is to actually ask our customers how we are doing. Surveys are one of the important tools that can be brought to bear on this issue. For many groups, surveying is the starting point for understanding what their patients, referring physicians, and other key stakeholders want. Groups can also find out what customers like and dislike about their experiences, and how groups compare with their competitors. This article provides a guide on how to get off to a good start in designing and deploying surveys that can help optimize the way groups take care of their patients and help their referring physicians.


Journal of The American College of Radiology | 2009

ACR White Paper: Task Force to Evaluate the Value Add Impact on Business Models

Frank J. Lexa; Jonathan W. Berlin; Giles W. Boland; Geoffrey G. Smith; Mark D. Jensen; David J. Seidenwurm; Richard T. Hoppe; Robert Stroud

Radiology practices are seeing both evolutionary and revolutionary changes in their business models. The Task Force to Evaluate the Value Add Impact on Business Models was charged with considering how radiologists and their practices add value in these novel settings. Both traditional and novel forms of added value were considered. Types of new business models that were evaluated included hybrid groups of radiologists and other practitioners, regional or national megagroups, and novel services both within and beyond the traditional purview of radiology practice. Recommendations for both how to measure and how to capture this value were considered at both the practice and national levels.


Journal of The American College of Radiology | 2010

The 2009 ACR Forum: Health Care Payment Models

Richard B. Gunderman; John A. Patti; Frank J. Lexa; Jeffrey C. Weinreb; Bruce J. Hillman; James H. Thrall; Harvey L. Neiman

The 2009 ACR Forum addressed health care payment models, the strengths and weaknesses of different models under consideration, their implications for radiology, and the role radiologists should play in the debate.


Journal of The American College of Radiology | 2010

Scenario Analysis and Strategic Planning: Practical Applications for Radiology Practices

Frank J. Lexa; Stephen Chan

Modern business science has many tools that can be of great value to radiologists and their practices. One of the most important and underused is long-term planning. Part of the problem has been the pace of change. Making a 5-year plan makes sense only if your develop robust scenarios of possible future conditions you will face. Scenario analysis is one of many highly regarded tools that can improve your predictive capability. However, as with many tools, it pays to have some training and to get practical tips on how to improve their value. It also helps to learn from other peoples mistakes rather than your own. The authors discuss both theoretical and practical issues in using scenario analysis to improve your planning process. They discuss actionable ways this set of tools can be applied in a group meeting or retreat.


Journal of The American College of Radiology | 2012

Drivers of Health Reform in the United States: 2012 and Beyond

Frank J. Lexa

American medicine has seen radical changes in the past decade. In particular, radiology has been affected, notably first with the passage of the Deficit Reduction Act in 2005 and then with the Patient Protection and Affordable Care Act in 2010. Health care reforms are not only driven by political agendas. This process is also a response to underlying social, economic, and technological realities. It is unlikely that reform efforts will just evaporate because of a single change in government or with a decision by the US Supreme Court. Regardless of who sits in the Oval Office and which party controls Congress, there are forces that will need to be addressed through policy changes in the coming years. The underlying drivers of health care reform are legion, but health care inflation, fiscal mismanagement by government, poor planning for demographic changes that affect entitlement programs, questions about the quality of health outcomes, and a desire for universal health care were all central factors in the reforms put forth since 2009. Radiologists should be preparing now for continued change in both the public and private sectors in health care for the foreseeable future. These changes are likely to have profound impacts on our profession. Radiologists and their groups should plan to pay greater attention to these events and should seek to have a much greater level of involvement in the political and social processes that lead to policy changes in health care.

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Jonathan W. Berlin

NorthShore University HealthSystem

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David C. Levin

Thomas Jefferson University Hospital

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Joseph C. McGowan

University of Pennsylvania

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