Franklin L. Ashley

FACE-LIFT COMPLICATIONS A Study of 922 Cases Performed in a 6-Year Period

Many articles have been published on the subject of face-lift complications.1–14 This review generally substantiates the findings of prior publications. In addition to listing the complications, an attempt was made to identify possible factors contributing to these complications. A brief summary of the current operative technique is included.

Carcinoma of the lip. A comparison of five year results after irradiation and surgical therapy.

Abstract In our series the data dealing with location, age, sex, duration, size, node involvement, and grading are comparable to those published elsewhere [2]. Correlation with exposure to the sun is lower than commonly reported. Eighty-seven per cent of the patients operated upon were free of tumor for five years. With radiotherapy 77 per cent were free of tumor. With reoperation the five year survival rate was 90 per cent for the surgical group and 91 per cent for the irradiated group. These values are also comparable to those previously published [2,3]. Cure rate of patients with involved nodes was relatively high (44 per cent) [4]. There was, as described in other reports, a definite inverse relationship between tumor size, duration, anaplasia, and curability [2–6]. It is interesting that 60 per cent of our patients with postirradiation recurrences were salvaged by subsequent operation.

Treatment of facial atrophy with liquid silicone

Abstract A series of fifteen patients with unilateral and bilateral atrophy of the face resulting from Rombergs disease and lipodystrophy have been successful treated with multiple injections of dimethylpolysiloxane (silicone) fluid. The earliest patient in this group of fifteen has been followed up for five years. No single instance of untoward reaction to the silicone fluid has been noted either locally or systemically. This form of treatment has achieved results far superior to those of any previous known method of therapy for these unfortunate patients. Until further experience is gained with this modality of treatment, it must necessarily be considered of an investigative nature and should be undertaken only under carefully controlled conditions.

The Current Status of Silicone Injection Therapy

Clinical uses of silicones. Factors influencing persistence of the original size of the injected area.

A New Treatment for Facial Hemiatrophy in Children by Injections of Dimethylpolysiloxane Fluid

Summary A new technic for the treatment of facial hemiatrophy (Rombergs disease) in children with multiple subcutaneous injections of dimethylpolysiloxane has been highly satisfactory. The technic is investigative in nature and will remain so for several years.

Studies on mammalian homotransplants of skin: III. An attempt to induce tolerance across the placenta in rats with RNA and DNA☆

Abstract A review of the more pertinent aspects of work pertaining to the present study as performed by others and by us is outlined. Four experiments are presented which represent our preliminary efforts to induce tolerance across the placental membrane in rats. In the first experiment, RNA was used and the results were slightly encouraging in that 18 per cent of the graft took in the twenty-day old animals (age of grafting) which represents a significant increase over the control animals (8 to 9 per cent). In the second experiment with DNA as the injected material, the difference between the percentage take of the treated animals and the control animals was negligible. Experiments 3 and 4 involved the use of DNA and RNA tagged with C 14 , in an effort to determine the quantity which actually entered the fetus through the placenta. This phase of the work is encouraging in that significant quantities of C 14 were counted in the fetuses, thus indicating passage of these cellular components. In view of our previous findings that tolerance may be produced by injecting RNA intracardially into neonatal rats and our present findings that the injected substances (DNA and RNA) crossed the placenta, we are hopeful of more significant results in future experiments with increased and repeated injections of modified antigen.

Use of the stapler in skin closure

The AutoSuture skin stapling instrument reduces operating room time and provides adequate skin closure for a wide variety of plastic surgical procedures.

Further studies in the survival of skin homografts as a function of quantity and frequency of RNA injections.

Abstract RNA prepared from the spleens of adult Wistar rats induced prolonged homograft survival when injected into neonatal Long Evans recipients, before the transplant of skin. The RNA derived from the spleen was at least as effective as the combined RNA prepared from either liver, spleen and thymus, or skin. The period of homograft survival increased with increasing quantity and frequency of RNA injection.

Cinefluorographic studies of deglutition and phonation: A preliminary report☆

Abstract In this preliminary report, a description of cinefluorographic instrumentation is presented. A basic diagnostic test to compare deglutition and phonation more efficaciously is outlined. Illustrations of the fundamental kinesiology necessary to produce American phonemes are included to complement the normal patients and patients with palatal incompetence.