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Dive into the research topics where Frédéric Pochard is active.

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Featured researches published by Frédéric Pochard.


Critical Care Medicine | 2000

Half the families of intensive care unit patients experience inadequate communication with physicians.

Elie Azoulay; Sylvie Chevret; Ghislaine Leleu; Frédéric Pochard; M. Barboteu; Christophe Adrie; Pierre Canouï; J. R. Le Gall; B. Schlemmer

ObjectiveEffective communication of simple, clear information to families of intensive care unit (ICU) patients is a vital component of quality care. The purpose of this study was to identify factors associated with poor comprehension by family members of the status of ICU patients. DesignProspective study. SettingUniversity-affiliated medical intensive care unit. Patients and MethodsA total of 102 patients admitted to an ICU for >2 days. InterventionThe representatives of 76 patients who were visited by at least one person during their ICU stay were interviewed. ResultsMean patient age was 54 ± 17 yrs and mean Simplified Acute Physiology Score II at admission was 40 ± 20. The representative was the spouse in 47 cases (62%). Among representatives, 25 (33%) were of foreign descent and 12 (16%) did not speak French. Mean duration of the first meeting with a physician was 10 ± 6 mins. In 34 cases (54%), the representative failed to comprehend the diagnosis, prognosis, or treatment of the patient.Factors associated with poor comprehension by representatives included patient-related, family-related, and physician- related factors. Patient-related factors included age <50 yrs (p = .03), unemployment (p = .01), referral from a hematology or oncology ward (p = .006), admission for acute respiratory failure (p = .005) or coma (p = .01), and a relatively favorable prognosis (p = .04). Family-related factors were foreign descent (p = .007), no knowledge of French (p = .03), representative not the spouse (p = .03), and no healthcare professional in the family (p = .01). Physician-related factors were first meeting with representative <10 mins (p = .03) and failure to give the representative an information brochure (p = .02). Moreover, after the first meeting, caregivers accurately predicted poor comprehension by representatives (p = .03). ConclusionsPatient information is frequently not communicated effectively to family members by ICU physicians. Physicians should strive to identify patients and families who require special attention and to determine how their personal style of interrelating with family members may impair communication.


Critical Care Medicine | 2001

Symptoms of anxiety and depression in family members of intensive care unit patients: Ethical hypothesis regarding decision-making capacity

Frédéric Pochard; Elie Azoulay; Sylvie Chevret; François Lemaire; Philippe Hubert; Pierre Canouï; Marc Grassin; Robert Zittoun; Jean-Roger Le Gall; Jean François Dhainaut; Benoît Schlemmer

ObjectiveAnxiety and depression may have a major impact on a person’s ability to make decisions. Characterization of symptoms that reflect anxiety and depression in family members visiting intensive care patients should be of major relevance to the ethics of involving family members in decision-making, particularly about end-of-life issues. DesignProspective multicenter study. SettingForty-three French intensive care units (37 adult and six pediatric); each unit included 15 patients admitted for longer than 2 days. PatientsSix hundred thirty-seven patients and 920 family members. InterventionsIntensive care unit characteristics and data on the patient and family members were collected. Family members completed the Hospital Anxiety and Depression Scale to allow evaluation of the prevalence and potential factors associated with symptoms of anxiety and depression. Measurements and Main ResultsOf 920 Hospital Anxiety and Depression Scale questionnaires that were completed by family members, all items were completed in 836 questionnaires, which formed the basis for this study. The prevalence of symptoms of anxiety and depression in family members was 69.1% and 35.4%, respectively. Symptoms of anxiety or depression were present in 72.7% of family members and 84% of spouses. Factors associated with symptoms of anxiety in a multivariate model included patient-related factors (absence of chronic disease), family-related factors (spouse, female gender, desire for professional psychological help, help being received by general practitioner), and caregiver-related factors (absence of regular physician and nurse meetings, absence of a room used only for meetings with family members). The multivariate model also identified three groups of factors associated with symptoms of depression: patient-related (age), family-related (spouse, female gender, not of French descent), and caregiver-related (no waiting room, perceived contradictions in the information provided by caregivers). ConclusionsMore than two-thirds of family members visiting patients in the intensive care unit suffer from symptoms of anxiety or depression. Involvement of anxious or depressed family members in end-of-life decisions should be carefully discussed.


Current Opinion in Critical Care | 2007

Burnout syndrome among critical care healthcare workers

Nathalie Embriaco; Laurent Papazian; Nancy Kentish-Barnes; Frédéric Pochard; Elie Azoulay

Purpose of reviewBurnout syndrome is a psychological state resulting from prolonged exposure to job stressors. Because ICUs are characterized by a high level of work-related stress, a factor known to increase the risk of burnout syndrome, we sought to review the available literature on burnout syndrome in ICU healthcare workers. Recent findingsBased on most recent studies, severe burnout syndrome (as measured using the Maslach Burnout Inventory) is present in about 50% of critical care physicians and in one third of critical care nurses. Strikingly, determinants of burnout syndrome are different in the two groups of caregivers. Namely, intensivists who have severe burnout syndrome are those with a high number of working hours (number of night shifts and time from last vacation) but determinants of severe burnout syndrome in ICU-nurses are related to ICU organization and end-of-life-related characteristics. ICU conflicts, however, were independent predictors of severe burnout syndrome in both groups. SummaryRecent studies reported high levels of severe burnout syndrome in ICU healthcare workers and identified potential targets for preventive strategies such as ICU working groups, communication strategies during end-of-life care and prevention and management of ICU conflicts.


Critical Care Medicine | 2001

Compliance with triage to intensive care recommendations.

Elie Azoulay; Frédéric Pochard; Sylvie Chevret; Christophe Vinsonneau; Maité Garrouste; Yves Cohen; Marie Thuong; Catherine Paugam; Corinne Apperre; Bertrand De Cagny; Frédéric Brun; Caroline Bornstain; Antoine Parrot; Fabienne Thamion; Jean Claude Lacherade; Yves Bouffard; Jean Roger Le Gall; Christian Herve; Marc Grassin; Robert Zittoun; Benoît Schlemmer; Jean François Dhainaut

Design Recommendations for triage to intensive care units (ICUs) have been issued but not evaluated. Setting In this prospective, multicenter study, all patients granted or refused admission to 26 ICUs affiliated with the French Society for Critical Care were included during a 1-month period. Characteristics of participating ICUs and patients, circumstances of triage, and description of the triage decision with particular attention to compliance with published recommendations were recorded. Results During the study period, 1,009 patients were and 283 were not admitted to the participating ICUs. Refused patients were more likely to be older than 65 yrs (odds ratio [OR], 3.53; confidence interval [CI], 1.98–5.32) and to have a poor chronic health status (OR, 3.09; CI, 2.05–4.67). An admission diagnosis of acute respiratory or renal failure, shock, or coma was associated with admission, whereas chronic severe respiratory and heart failure or metastatic disease without hope of remission were associated with refusal (OR, 2.24; CI, 1.38–3.64). Only four (range, 0–8) of the 20 recommendations for triage to ICU were observed; a full unit and triage over the phone were associated with significantly poorer compliance with recommendations (0 [0–2] vs. 6 [2–9], p = .0003; and 1 [0–6] vs. 6 [1–9], p < .0001; respectively). Conclusion Recommendations for triage to intensive care are rarely observed, particularly when the unit is full or triage is done over the phone. These recommendations may need to be redesigned to improve their practicability under real-life conditions, with special attention to phone triage and triaging to a full unit.


Critical Care Medicine | 2012

Impact of an intensive care unit diary on psychological distress in patients and relatives

Maité Garrouste-Orgeas; Isaline Coquet; Antoine Perier; Jean-François Timsit; Frédéric Pochard; Frédéric Lancrin; François Philippart; Aurélien Vesin; Cédric Bruel; Youssef Blel; Stéphanie Angeli; Natalie Cousin; Benoit Misset

Objective:To assess the impact of an intensive care unit diary on the psychological well-being of patients and relatives 3 and 12 months after intensive care unit discharge. Design:Prospective single-center study with an intervention period between two control periods. Setting:Medical-surgical intensive care unit in a 460-bed tertiary hospital. Patients:Consecutive patients from May 2008 to November 2009 and their relatives. Study inclusion occurred after the fourth day in the intensive care unit. Interventions:A diary written by both the patient’s relatives and the intensive care unit staff. Measurements and Main Results:Patients and relatives completed the Hospital Anxiety and Depression Scale and Peritraumatic Dissociative Experiences Questionnaire 3 months after intensive care unit discharge, and completed the Impact of Events Scale assessing posttraumatic stress–related symptoms 12 months after intensive care unit discharge. Of the 378 patients admitted during the study period, 143 were included (48 in the prediary period, 49 in the diary period, and 46 in the postdiary period). In relatives, severe posttraumatic stress–related symptoms after 12 months varied significantly across periods (prediary 80%, diary 31.7%, postdiary 67.6%; p<.0001). Similar results were obtained in the posttraumatic stress–related symptom score after 12 months in the surviving patients (prediary 34.6 ± 15.9, diary 21 ± 12.2, and postdiary 29.8 ± 15.9; p = .02). Conclusions:The intensive care unit diary significantly affected posttraumatic stress–related symptoms in relatives and surviving patients 12 months after intensive care unit discharge.


Critical Care Medicine | 2003

Determinants of postintensive care unit mortality: a prospective multicenter study.

Elie Azoulay; Christophe Adrie; Arnaud de Lassence; Frédéric Pochard; Delphine Moreau; Guillaume Thiery; Christine Cheval; Pierre Moine; Maité Garrouste-Orgeas; Corinne Alberti; Yves Cohen; Jean-François Timsit

ObjectiveSix to 25 percent of patients discharged alive from the intensive care unit (ICU) die before hospital discharge. Although this post-ICU mortality may indicate premature discharge from a full ICU or suboptimal management in the ICU or ward, another factor may be discharge from the ICU as part of a decision to limit treatment of hopelessly ill patients. We investigated determinants of post-ICU mortality, with special attention to this factor. DesignProspective, multicenter, database study. SettingSeven ICUs in or near Paris, France. PatientsA total of 1,385 patients who were discharged alive from an ICU after a stay of ≥48 hrs; 150 (10.8%) died before hospital discharge. Decisions to withhold or withdraw life-sustaining treatments were implemented in the ICUs in 80 patients, including 47 (58.7%) who died before hospital discharge. InterventionsNone. Measurements and Main ResultsIn the univariate analysis, post-ICU mortality was associated with advanced age, poor chronic health status, severe comorbidities, severity and organ failure scores (Simplified Acute Physiology Score II, sepsis-related organ failure assessment, and Logistic Organ Dysfunction at admission and at ICU discharge), decisions to withhold or withdraw life-sustaining treatments, and Omega score (reflecting ICU resource utilization and length of ICU stay). Multivariate stepwise logistic regression identified five independent determinants of post-ICU mortality: McCabe class 1 (odds ratio, 0.388 [95% confidence interval, 0.26–0.58]), transfer from a ward (odds ratio, 1.89 [95% confidence interval, 1.27–2.80]), Simplified Acute Physiology Score II score at admission >36 (odds ratio, 1.57 [95% confidence interval, 1.6–2.33]), decisions to withhold or withdraw life-sustaining treatments (odds ratio, 9.64 [95% confidence interval, 5.75–16.6]), and worse sepsis-related organ failure assessment score at discharge (odds ratio, 1.11 [95% confidence interval, 1.03–1.18] per point). ConclusionsMore than 10% of ICU survivors died before hospital discharge. Determinants of post-ICU mortality included variables reflecting patient status before and during the ICU stay. However, the most powerful predictor of post-ICU mortality was the decision to withhold or withdraw life-sustaining treatments in the ICU, suggesting that the decision has been made not to use the unique services of the ICU for these patients.


Critical Care Medicine | 2001

French intensivists do not apply American recommendations regarding decisions to forgo life-sustaining therapy.

Frédéric Pochard; Elie Azoulay; Sylvie Chevret; Christophe Vinsonneau; Marc Grassin; François Lemaire; Christian Herve; Benoît Schlemmer; Robert Zittoun; Jean-François Dhainaut

ObjectiveRecommendations for making and implementing decisions to forgo life-sustaining therapy in intensive care units have been developed in the United States, but the extent that they are realized in practice has yet to be measured. DesignProspective, multicenter, 4-wk study. For each patient with an implemented decision to forgo life-sustaining therapy, the deliberation and decision implementation procedures were recorded. SettingFrench intensive care units. PatientsAll consecutive patients admitted to 26 French intensive care units. InterventionsNone. Measurements and Main Results Of 1,009 patients admitted, 208 died in the intensive care unit. A decision to forgo life-sustaining therapy was implemented in 105 patients. The number of supportive treatments forgone was 2.3 ± 1.7 per patient. Decisions to forgo sustaining therapy were preceded by 3.5 ± 2.5 deliberation sessions. Proxies were informed of the deliberations in 62 (59.1%) cases but participated in only 18 (17.1%) decisions. The patient’s perception of his or her quality of life was rarely evaluated (11.5%), and only rarely did the decision involve evaluating the patient’s wishes (7.6%), the patient’s religious values (7.6%), or the cost of treatment (7.6%). Factors most frequently evaluated were medical team advice (95.3%), predicted reversibility of acute disease (90.5%), underlying disease severity (83.9%), and the patient’s quality of life as evaluated by caregivers (80.1%). ConclusionsA decision to withhold or withdraw life-sustaining therapy was implemented for half the patients who died in the French intensive care units studied. In many cases, the decision was taken without regard for one or more factors identified as relevant in U.S. guidelines.


Critical Care Medicine | 2009

Assessing burden in families of critical care patients.

Nancy Kentish-Barnes; Virginie Lemiale; Marine Chaize; Frédéric Pochard; Elie Azoulay

Objective:To provide critical care clinicians with information on validated instruments for assessing burden in families of critical care patients. Data Sources:PubMed (1979–2009). Study Selection:We included all quantitative studies that used a validated instrument to evaluate the prevalence of, and risk factors for, burden on families. Data Extraction and Synthesis:We extracted the descriptions of the instruments used and the main results. Family burden after critical illness can be detected reliably and requires preventive strategies and specific treatments. Using simple face-to-face interviews, intensivists can learn to detect poor comprehension and its determinants. Instruments for detecting symptoms of anxiety, depression, or stress can be used reliably even by physicians with no psychiatric training. For some symptoms, the evaluation should take place at a distance from intensive care unit discharge or death. Experience with families of patients who died in the intensive care unit and data from the literature have prompted studies of bereaved family members and the development of interventions aimed at decreasing guilt and preventing complicated grief. Conclusions:We believe that burden on families should be assessed routinely. In clinical studies, using markers for burden measured by validated tools may provide further evidence that effective communication and efforts to detect and to prevent symptoms of stress, anxiety, or depression provide valuable benefits to families.


Critical Care Medicine | 2003

Opinions about surrogate designation: a population survey in France.

Elie Azoulay; Frédéric Pochard; Sylvie Chevret; Christophe Adrie; Pierre-Edouard Bollaert; Frédéric Brun; Didier Dreyfuss; Maité Garrouste-Orgeas; Dany Goldgran-Toledano; Mercé Jourdain; Michel Wolff; Jean-Roger Le Gall; Benoît Schlemmer

OBJECTIVE Many patients go through periods when they are too ill to give consent or to participate in decisions. When this occurs, patient autonomy is best maintained when a surrogate designated by the patient and familiar with his or her values can speak for the patient. The objective of this study was to determine whether people who are not yet ill are ready to accept surrogate designation. Attitudes toward family participation in care were explored also. DESIGN Population survey by telephone. Because refusal of life-sustaining treatment is a dramatic example of patient autonomy, the survey used questions about ICU admission. SETTING General population in France. SUBJECTS Representative random sample of 8000 residents of France aged 18 yrs or more. INTERVENTIONS None. MAIN OUTCOME MEASURES The survey investigated attitudes. RESULTS Most respondents said they would like to designate a surrogate (7205 [90%]) and to have their family share in their care (6691 [84%] for bathing, 5629 [70%] for feeding, and 4139 [52%] for tracheal suctioning) and in decisions about their management (6120 [76%]). Among respondents with a spouse, 79% said they would designate the spouse to speak for them. The attitudes were not influenced by ethnicity, religion or education level. CONCLUSIONS Most people living in France would want a surrogate to represent them should they be incompetent and admitted to an ICU. Primary care physicians should inform their patients about the benefits of discussing illness-related issues among friends and family.


Critical Care Medicine | 2011

Postintensive care unit psychological burden in patients with chronic obstructive pulmonary disease and informal caregivers: A multicenter study

Sandra de Miranda; Frédéric Pochard; Marine Chaize; Bruno Mégarbane; Antoine Cuvelier; Nicolas Bele; Jésus Gonzalez-Bermejo; Jerome Aboab; Alexandre Lautrette; Virginie Lemiale; Nicolas Roche; Marina Thirion; Sylvie Chevret; Benoît Schlemmer; Thomas Similowski; Elie Azoulay

Objective:To determine the prevalence and risk factors of symptoms of anxiety, depression, and posttraumatic stress disorder-related symptoms in patients with chronic obstructive pulmonary disease and their relatives after an intensive care unit stay. Design:Prospective multicenter study. Setting:Nineteen French intensive care units. Subjects:One hundred twenty-six patients with chronic obstructive pulmonary disease who survived an intensive care unit stay and 102 relatives. Intervention:None. Measurements and Main Results:Patients and relatives were interviewed at intensive care unit discharge and 90 days later to assess symptoms of anxiety and depression using Hospital Anxiety and Depression Scale (HADS) and posttraumatic stress disorder-related symptoms using the Impact of Event Scale (IES). At intensive care unit discharge, 90% of patients recollected traumatic psychological events in the intensive care unit. At day 90, we were able to conduct telephone interviews with 53 patients and 47 relatives. Hospital Anxiety and Depression Scale scores indicated symptoms of anxiety and depression in 52% and 45.5% of patients at intensive care unit discharge and in 28.3% and 18.9% on day 90, respectively. Corresponding prevalence in relatives were 72.2% and 25.7% at intensive care unit discharge and 40.4% and 14.9% on day 90, respectively. The Impact of Event Scale indicated posttraumatic stress disorder-related symptoms in 20.7% of patients and 29.8% of relatives on day 90. Peritraumatic dissociation assessed using the Peritraumatic Dissociative Experiences Questionnaire was independently associated with posttraumatic stress disorder-related symptoms in the patients and relatives. Previous intensive care unit experience and recollection of bothersome noise in the intensive care unit predicted posttraumatic stress disorder-related symptoms in the patients. Conclusions:Psychiatric symptoms were found to be common in a group of 126 patients with chronic obstructive pulmonary disease who survived an intensive care unit stay and their relatives at intensive care unit discharge and 90 days later. Peritraumatic dissociation at intensive care unit discharge was found to independently predict posttraumatic stress disorder-related symptoms in this sample of patients and relatives.

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