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Dive into the research topics where Frederic Starr is active.

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Featured researches published by Frederic Starr.


Journal of Trauma-injury Infection and Critical Care | 2009

CT should replace three-view radiographs as the initial screening test in patients at high, moderate, and low risk for blunt cervical spine injury: a prospective comparison.

John Bailitz; Frederic Starr; Matthew Beecroft; Jon Bankoff; Roxanne R. Roberts; Faran Bokhari; Kimberly Joseph; Dorian Wiley; Andrew J. Dennis; Susan Gilkey; Paul Erickson; Patricia Raksin; Kimberly Nagy

BACKGROUND An estimated 10,000 Americans suffer cervical spine injuries each year. More than 800,000 cervical spine radiographs (CSR) are ordered annually. The human and healthcare costs associated with these injuries are enormous especially when diagnosis is delayed. Controversy exists in the literature concerning the diagnostic accuracy of CSR, with reported sensitivity ranging from 32% to 89%. We sought to compare prospectively the sensitivity of cervical CT (CCT) to CSR in the initial diagnosis of blunt cervical spine injury for patients meeting one or more of the NEXUS criteria. METHODS The study prospectively compared the diagnostic accuracy of CSR to CCT in consecutive patients evaluated for blunt trauma during 23 months at an urban, public teaching hospital and Level I Trauma Center. Inclusion criteria were adult patient, evaluated for blunt cervical spine injury, meeting one or more of the NEXUS criteria. All patients received both three-view CSR and CCT as part of a standard diagnostic protocol. Each CSR and CCT study was interpreted independently by a different radiology attending who was blinded to the results of the other study. Clinically significant injuries were defined as those requiring one or more of the following interventions: operative procedure, halo application, and/or rigid cervical collar. RESULTS Of 1,583 consecutive patients evaluated for blunt cervical spine trauma, 78 (4.9%) patients received only CCT or CSR and were excluded from the study. Of the remaining 1,505 patients, 78 (4.9%) had evidence of a radiographic injury by CSR or CCT. Of these 78 patients with radiographic injury, 50 (3.3%) patients had clinically significant injuries. CCT detected all patients with clinically significant injuries (100% sensitive), whereas CSR detected only 18 (36% sensitive). Of the 50 patients, 15 were at high risk, 19 at moderate risk, and 16 at low risk for cervical spine injury according to previously published risk stratification. CSR detected clinically significant injury in 7 high risk (46% sensitive), 7 moderate risk (37% sensitive), and 4 low risk patients (25% sensitive). CONCLUSION Our results demonstrate the superiority of CCT compared with CSR for the detection of clinically significant cervical spine injury. The improved ability to exclude injury rapidly provides further evidence that CCT should replace CSR for the initial evaluation of blunt cervical spine injury in patients at any risk for injury.


Journal of Trauma-injury Infection and Critical Care | 2008

Taser X26 Discharges in Swine: Ventricular Rhythm Capture is Dependent on Discharge Vector

Daniel J. Valentino; Robert J. Walter; Andrew J. Dennis; Bosko Margeta; Frederic Starr; Kimberly Nagy; Faran Bokhari; Dorion Wiley; Kimberly Joseph; Roxanne R. Roberts

BACKGROUND Data from our previous studies indicate that Taser X26 stun devices can acutely alter cardiac function in swine. We hypothesized that most transcardiac discharge vectors would capture ventricular rhythm, but that other vectors, not traversing the heart, would fail to capture the ventricular rhythm. METHODS Using an Institutional Animal Care and Use Committee (IACUC) approved protocol, four Yorkshire pigs (25-36 kg) were anesthetized, paralyzed with succinylcholine (2 mg/kg), and then exposed to 10 second discharges from a police-issue Taser X26. For most discharges, the barbed darts were pushed manually into the skin to their full depth (12 mm) and were arranged in either transcardiac (such that a straight line connecting the darts would cross the region of the heart) or non-transcardiac vectors. A total of 11 different vectors and 22 discharge conditions were studied. For each vector, by simply rotating the cartridge 180-degrees in the gun, the primary current-emitting dart was changed and the direction of current flow during the discharge was reversed without physically moving the darts. Echocardiography and electrocardiograms (ECGs) were performed before, during, and after all discharges. p values < 0.05 were considered significant. RESULTS ECGs were unreadable during the discharges because of electrical interference, but echocardiography images clearly demonstrated that ventricular rhythm was captured immediately in 52.5% (31 of 59) of the discharges on the ventral surface of the animal. In each of these cases, capture of the ventricular rhythm with rapid ventricular contractions consistent with ventricular tachycardia (VT) or flutter was seen throughout the discharge. A total of 27 discharges were administered with transcardiac vectors and ventricular capture occurred in 23 of these discharges (85.2% capture rate). A total of 32 non-transcardiac discharges were administered ventrally and capture was seen in only eight of these (25% capture rate). Ventricular fibrillation (VF) was seen with two vectors, both of which were transcardiac. In the remaining animals, VT occurred postdischarge until sinus rhythm was regained spontaneously. CONCLUSIONS For most transcardiac vectors, Taser X26 caused immediate ventricular rhythm capture. This usually reverted spontaneously to sinus rhythm but potentially fatal VF was seen with two vectors. For some non-transcardiac vectors, capture was also seen but with a significantly (p < 0.0001) decreased incidence.


Journal of Trauma-injury Infection and Critical Care | 2012

Screening for traumatic stress among survivors of urban trauma.

Carol Reese; Tabitha Pederson; Susan Avila; Kimberly Joseph; Kimberly Nagy; Andrew J. Dennis; Dorion Wiley; Frederic Starr; Faran Bokhari

OBJECTIVE This study piloted the use of the Primary Care PTSD (PC-PTSD) screening tool in an outpatient setting to determine its utility for broader use and to gather data on traumatic stress symptoms among direct (patients) and indirect (families) survivors of traumatic injuries. METHODS Using the PC-PTSD plus one question exploring openness to seeking help, participants were screened for PTSD in the outpatient clinic of an urban Level 1 trauma center. The survey was distributed during a 23-week period from April to September 2011. The screen was self-administered, a sample of convenience, and participation was voluntary and anonymous. RESULTS With a response rate of 66%, 307 surveys were completed. Forty-two percent of participants had a positive screen. Patients greater than 30 and 90 days from injury had 1.5 and 1.7 times more positive screens than those less than 30 days. Patients with gunshot wounds were 13 times as likely as those with falls and twice as likely as those in a motor vehicle crash to have a positive screen. Sixty percent of patients with a positive screen noted it would be helpful to talk to someone. CONCLUSION The PC-PTSD was an easy to administer screening tool. Patients reported PTSD symptoms at higher rates than previous studies. Patients with gunshot wounds and those injured greater than 30 days from the time of the screen were more likely to report PTSD symptoms. Although males represented 82% of positive screens, there was no statistical difference in PTSD symptoms between male and female participants because of the small number of females represented. Families also reported significant levels of PTSD. Both patients and families may benefit from additional screening and intervention in the early posttrauma period. LEVEL OF EVIDENCE Epidemiologic study, level IV.


Journal of Trauma-injury Infection and Critical Care | 2017

Management of adult pancreatic injuries: A practice management guideline from the Eastern Association for the Surgery of Trauma.

Vanessa P. Ho; Nimitt J. Patel; Faran Bokhari; Firas Madbak; Jana Hambley; James R. Yon; Bryce R.H. Robinson; Kimberly Nagy; Scott B. Armen; Samuel Kingsley; Sameer Gupta; Frederic Starr; Henry R. Moore; Uretz J. Oliphant; Elliott R. Haut; John J. Como

BACKGROUND Traumatic injury to the pancreas is rare but is associated with significant morbidity and mortality, including fistula, sepsis, and death. There are currently no practice management guidelines for the medical and surgical management of traumatic pancreatic injuries. The overall objective of this article is to provide evidence-based recommendations for the physician who is presented with traumatic injury to the pancreas. METHODS The MEDLINE database using PubMed was searched to identify English language articles published from January 1965 to December 2014 regarding adult patients with pancreatic injuries. A systematic review of the literature was performed, and the Grading of Recommendations Assessment, Development and Evaluation framework was used to formulate evidence-based recommendations. RESULTS Three hundred nineteen articles were identified. Of these, 52 articles underwent full text review, and 37 were selected for guideline construction. CONCLUSION Patients with grade I/II injuries tend to have fewer complications; for these, we conditionally recommend nonoperative or nonresectional management. For grade III/IV injuries identified on computed tomography or at operation, we conditionally recommend pancreatic resection. We conditionally recommend against the routine use of octreotide for postoperative pancreatic fistula prophylaxis. No recommendations could be made regarding the following two topics: optimal surgical management of grade V injuries, and the need for routine splenectomy with distal pancreatectomy. LEVEL OF EVIDENCE Systematic review, level III.


Journal of Trauma-injury Infection and Critical Care | 2013

Not so fast to skin graft: Transabdominal wall traction closes most ''domain loss'' abdomens in the acute setting

Andrew J. Dennis; Thomas A. Vizinas; Kimberly Joseph; Samuel Kingsley; Faran Bokhari; Frederic Starr; Stathis Poulakidas; Dorion Wiley; Thomas Messer; Kimberly Nagy

BACKGROUND Damage-control laparotomy (DCL) has revolutionized the surgery of injury. However, this has led to the dilemma of the nonclosable abdomen. Subsequently, there exists a subgroup of patients who after resuscitation and diuresis, remain nonclosable. Before the adoption of our open abdomen protocol (OAP) and use of transabdominal wall traction (TAWT), these patients required skin grafting and a planned ventral hernia. We hypothesize that our OAP and TAWT device, which use full abdominal wall thickness sutures to dynamically distribute midline traction, achieve an improved method of fascial reapproximation. METHODS From 2008 to 2011, all DCL and decompressive laparotomy patients in our urban trauma center were managed by our OAP. Thirty two were noncloseable “domain loss abdomens” after achieving physiologic steady state and near dry weight. All patients received the TAWT device when near dry weight was achieved. Wound size, days to closure, days to TAWT, and TAWT to closure were tracked. RESULTS During this 36-month period, OAP/TAWT was applied to 32 patients. All patients demonstrated domain loss precluding fascial closure. Average wound size was 18.5-cm width by 30.5-cm length. Mean time DCL surgery to TAWT was 9.5 days. At time of placement, TAWT decreased initial wound width by an average of 9.8 cm (51.4%). Patients returned to the operating room for tightening/washout an average of 2.2 times (excluding TAWT insertion and final closure operations). Mean time TAWT to closure was 8.7 days. Mean time from admission surgery to primary closure was 18.2 days. All patients achieved primary fascial closure using this method without components separation or biologic bridge operations. CONCLUSION OAP/TAWT has revolutionized the way we manage “domain loss” open abdomen patients and has virtually eliminated the acceptance of planned ventral hernia. TAWT consistently recaptures lost domain, preserves the leading fascial edge, and eliminates the need for biologic bridges, components separation, or skin grafting. LEVEL OF EVIDENCE Therapeutic study, level III.


Journal of Trauma-injury Infection and Critical Care | 2016

Aortocaval fistula and celiac artery transection after gunshot wound.

James R. Yon; Charles Fredericks; Frederic Starr; Faran Bokhari; Laura J. Moore

A 22-year-old male patient presented after a single gunshot wound, overlying the lateral 10th rib. He was alert and responding to commands but was tachycardic and hypotensive. A central line was placed, and the patient was a transient responder to fluids and 2 U of un–cross-matched blood initially. The patient was dyspneic but had equal breath sounds. Chest radiograph revealed a right hemothorax with missile overlying the right lateral chest wall, concerning for a combination of transmediastinal and upper abdominal injury (Fig. 1). A right chest tube was placed with 700-mL initial output. Ultrasound of the heart was normal without pericardial fluid. The patient became hypotensive again with increasing upper abdominal pain, and our massive transfusion protocol was initiated. Because of increased work of


Plastic and Reconstructive Surgery | 2015

Trans-abdominal wall traction as a universal solution to the management of giant ventral hernias.

Andrew J. Dennis; Reza Salabat; Samuel Kingsley; Frederic Starr; Kimberly Joseph; Dorion Wiley; Thomas Messer; Stathis Poulakidas; Kimberly Nagy; Faran Bokhari

Background: Domain loss following damage-control laparotomy is a challenging problem many surgeons face. The authors recently developed trans–abdominal wall traction, which closed 100 percent of domain loss abdomens in the acute setting. They hypothesized that it can be used successfully in patients with chronic giant ventral defects. Methods: From 2008 to 2013, 44 patients with acute loss of domain and 10 with chronically giant ventral defects were enrolled in the open abdomen protocol with subsequent placement of the trans–abdominal wall traction device. Results: Patients’ average age in the acute and chronic groups was 28.2 and 35.3 years and average body mass index was 26.4 and 32.4 kg/m2, respectively. Ventral hernia size was reduced with the first trans–abdominal wall traction insertion from 610.5 cm2 to 274.6 cm2 in the acute setting and from 598 cm2 to 236.9 cm2 in the chronic setting. Average time from damage-control laparotomy to device insertion was 12.9 days in the acute group and more than 3 years in the chronic group. Lost domain was achieved with an average of less than 2.5 trans–abdominal wall traction tightenings, correlating to 9.2 and 8.2 days in the acute and chronic groups, respectively. Enterocutaneous fistula occurrence was 9 percent in the acute group and 0 percent in the chronic group. Conclusions: All patients were successfully closed after reestablishment of the lost domain. Trans–abdominal wall traction is an effective means of reestablishing abdominal domain and achieving primary abdominal wall closure in all patients with giant ventral defects, both acute and chronic. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.


Journal of Burn Care & Research | 2018

Placenta to the Rescue: Limb Salvage Using Dehydrated Human Amnion/Chorion Membrane

Victoria Schlanser; Andrew J. Dennis; Katarina Ivkovic; Kimberly Joseph; Matthew Kaminsky; Thomas Messer; Stathis Poulakidas; Frederic Starr; Faran Bokhari

Reconstruction of skin and soft tissue wounds can pose a unique surgical challenge. This is especially true for cases of exposed bone and tendon where soft tissue loss is extensive and opportunities for tissue advancement or rotation are limited. A clinical case is presented describing an experience with dehydrated human amnion/chorion membrane (dHACM, EpiFix®/AmnioFix®, MiMedx Group, Marietta, GA) graft to obtain granulation over an open fracture with desiccated bone. The 22-year-old female trauma patient presented with high-grade bilateral lower extremity soft tissue loss after being run over and dragged by a semitruck. Despite several weeks of serial debridemonts, the right distal fibula and left medial femur remained desiccated and infected. Both extremities had cavernous tissue landscapes with minimal granulation tissue and neither was hospitable for split thickness skin grafting. Four separate applications of dHACM (combination of EpiFix® and AmnioFix®) to the affected areas of exposed bone were successful at stimulating a robust granulation bed. On hospital days 44 and 61, the wounds were successfully skin grafted. The authors suspect that the dHACM applications contributed to successful granulation coverage to the affected bones that were otherwise not amendable to other coverage options. This contributed to limb salvage and a successful outcome.


American Surgeon | 2015

Outcomes in traumatic brain injury for patients presenting on antiplatelet therapy.

John D avid Cull; Lauren M. Sakai; Imran Sabir; Brent Johnson; Andrew Tully; Kimberly Nagy; Andrew J. Dennis; Frederic Starr; Kimberly Joseph; Dorion Wiley; Henry R. Moore; Uretz J. Oliphant; Faran Bokhari


American Journal of Surgery | 2018

The “TRAUMA LIFE” initiative: The impact of a multidisciplinary checklist process on outcomes and communication in a Trauma Intensive Care Unit

Kimberly Joseph; Sameer Gupta; James R. Yon; Renee Partida; Lee Cartagena; John C. Kubasiak; Vanessa Buie; Jared Miller; Dorion Wiley; Kimberly Nagy; Frederic Starr; Andrew J. Dennis; Matthew Kaminsky; Faran Bokhari

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Andrew J. Dennis

Rush University Medical Center

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Kimberly Joseph

Rush University Medical Center

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Kimberly Nagy

Rush University Medical Center

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Dorion Wiley

Rush University Medical Center

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Stathis Poulakidas

Loyola University Medical Center

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Henry R. Moore

Carle Foundation Hospital

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