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Dive into the research topics where Fredrik Sebelius is active.

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Featured researches published by Fredrik Sebelius.


Expert Review of Medical Devices | 2013

Sensory feedback in upper limb prosthetics

Christian Antfolk; Marco D'Alonzo; Birgitta Rosén; Göran Lundborg; Fredrik Sebelius; Christian Cipriani

One of the challenges facing prosthetic designers and engineers is to restore the missing sensory function inherit to hand amputation. Several different techniques can be employed to provide amputees with sensory feedback: sensory substitution methods where the recorded stimulus is not only transferred to the amputee, but also translated to a different modality (modality-matched feedback), which transfers the stimulus without translation and direct neural stimulation, which interacts directly with peripheral afferent nerves. This paper presents an overview of the principal works and devices employed to provide upper limb amputees with sensory feedback. The focus is on sensory substitution and modality matched feedback; the principal features, advantages and disadvantages of the different methods are presented.


IEEE Transactions on Neural Systems and Rehabilitation Engineering | 2011

Online Myoelectric Control of a Dexterous Hand Prosthesis by Transradial Amputees

Christian Cipriani; Christian Antfolk; Marco Controzzi; Göran Lundborg; Birgitta Rosén; Maria Chiara Carrozza; Fredrik Sebelius

A real-time pattern recognition algorithm based on k-nearest neighbors and lazy learning was used to classify, voluntary electromyography (EMG) signals and to simultaneously control movements of a dexterous artificial hand. EMG signals were superficially recorded by eight pairs of electrodes from the stumps of five transradial amputees and forearms of five able-bodied participants and used online to control a robot hand. Seven finger movements (not involving the wrist) were investigated in this study. The first objective was to understand whether and to which extent it is possible to control continuously and in real-time, the finger postures of a prosthetic hand, using superficial EMG, and a practical classifier, also taking advantage of the direct visual feedback of the moving hand. The second objective was to calculate statistical differences in the performance between participants and groups, thereby assessing the general applicability of the proposed method. The average accuracy of the classifier was 79% for amputees and 89% for able-bodied participants. Statistical analysis of the data revealed a difference in control accuracy based on the aetiology of amputation, type of prostheses regularly used and also between able-bodied participants and amputees. These results are encouraging for the development of noninvasive EMG interfaces for the control of dexterous prostheses.


PLOS ONE | 2014

Self-powered wireless carbohydrate/oxygen sensitive biodevice based on radio signal transmission

Magnus Falk; Miguel Alcalde; Philip N. Bartlett; Antonio L. De Lacey; Lo Gorton; Cristina Gutierrez-Sanchez; Raoudha Haddad; Jeremy D. Kilburn; Dónal Leech; Roland Ludwig; Edmond Magner; Diana M. Mate; Peter Ó Conghaile; Roberto Ortiz; Marcos Pita; Sascha Pöller; Tautgirdas Ruzgas; Urszula Salaj-Kosla; Wolfgang Schuhmann; Fredrik Sebelius; Minling Shao; Leonard Stoica; Cristoph Sygmund; Jonas Tilly; Miguel D. Toscano; Jeevanthi Vivekananthan; Emma Wright; Sergey Shleev

Here for the first time, we detail self-contained (wireless and self-powered) biodevices with wireless signal transmission. Specifically, we demonstrate the operation of self-sustained carbohydrate and oxygen sensitive biodevices, consisting of a wireless electronic unit, radio transmitter and separate sensing bioelectrodes, supplied with electrical energy from a combined multi-enzyme fuel cell generating sufficient current at required voltage to power the electronics. A carbohydrate/oxygen enzymatic fuel cell was assembled by comparing the performance of a range of different bioelectrodes followed by selection of the most suitable, stable combination. Carbohydrates (viz. lactose for the demonstration) and oxygen were also chosen as bioanalytes, being important biomarkers, to demonstrate the operation of the self-contained biosensing device, employing enzyme-modified bioelectrodes to enable the actual sensing. A wireless electronic unit, consisting of a micropotentiostat, an energy harvesting module (voltage amplifier together with a capacitor), and a radio microchip, were designed to enable the biofuel cell to be used as a power supply for managing the sensing devices and for wireless data transmission. The electronic system used required current and voltages greater than 44 µA and 0.57 V, respectively to operate; which the biofuel cell was capable of providing, when placed in a carbohydrate and oxygen containing buffer. In addition, a USB based receiver and computer software were employed for proof-of concept tests of the developed biodevices. Operation of bench-top prototypes was demonstrated in buffers containing different concentrations of the analytes, showcasing that the variation in response of both carbohydrate and oxygen biosensors could be monitored wirelessly in real-time as analyte concentrations in buffers were changed, using only an enzymatic fuel cell as a power supply.


Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery | 2009

Referral of sensation to an advanced humanoid robotic hand prosthesis.

Birgitta Rosén; H. Henrik Ehrsson; Christian Antfolk; Christian Cipriani; Fredrik Sebelius; Göran Lundborg

Hand prostheses that are currently available on the market are used by amputees to only a limited extent, partly because of lack of sensory feedback from the artificial hand. We report a pilot study that showed how amputees can experience a robot-like advanced hand prosthesis as part of their own body. We induced a perceptual illusion by which touch applied to the stump of the arm was experienced from the artificial hand. This illusion was elicited by applying synchronous tactile stimulation to the hidden amputation stump and the robotic hand prosthesis in full view. In five people who had had upper limb amputations this stimulation caused referral touch sensation from the stump to the artificial hand, and the prosthesis was experienced more like a real hand. We also showed that this illusion can work when the amputee controls the movements of the artificial hand by recordings of the arm muscle activity with electromyograms. These observations indicate that the previously described “rubber hand illusion” is also valid for an advanced hand prosthesis, even when it has a robotic-like appearance.


IEEE Transactions on Neural Systems and Rehabilitation Engineering | 2013

Artificial Redirection of Sensation From Prosthetic Fingers to the Phantom Hand Map on Transradial Amputees: Vibrotactile Versus Mechanotactile Sensory Feedback

Christian Antfolk; Marco D'Alonzo; Marco Controzzi; Göran Lundborg; Birgitta Rosén; Fredrik Sebelius; Christian Cipriani

This work assesses the ability of transradial amputees to discriminate multi-site tactile stimuli in sensory discrimination tasks. It compares different sensory feedback modalities using an artificial hand prosthesis in: 1) a modality matched paradigm where pressure recorded on the five fingertips of the hand was fed back as pressure stimulation on five target points on the residual limb; and 2) a modality mismatched paradigm where the pressures were transformed into mechanical vibrations and fed back. Eight transradial amputees took part in the study and were divided in two groups based on the integrity of their phantom map; group A had a complete phantom map on the residual limb whereas group B had an incomplete or nonexisting map. The ability in localizing stimuli was compared with that of 10 healthy subjects using the vibration feedback and 11 healthy subjects using the pressure feedback (in a previous study), on their forearms, in similar experiments. Results demonstrate that pressure stimulation surpassed vibrotactile stimulation in multi-site sensory feedback discrimination. Furthermore, we demonstrate that subjects with a detailed phantom map had the best discrimination performance and even surpassed healthy participants for both feedback paradigms whereas group B had the worst performance overall. Finally, we show that placement of feedback devices on a complete phantom map improves multi-site sensory feedback discrimination, independently of the feedback modality.


Journal of Medical Engineering & Technology | 2006

Myoelectric control of a computer animated hand: A new concept based on the combined use of a tree-structured artificial neural network and a data glove

Fredrik Sebelius; Lars Eriksson; Christian Balkenius; Thomas Laurell

This paper proposes a new learning set-up in the field of control systems for multifunctional hand prostheses. Two male subjects with a traumatic one-hand amputation performed simultaneous symmetric movements with the healthy and the phantom hand. A data glove on the healthy hand was used as a reference to train the system to perform natural movements. Instead of a physical prosthesis with limited degrees of freedom, a virtual (computer-animated) hand was used as the target tool. Both subjects successfully performed seven different motoric actions with the fingers and wrist. To reduce the training time for the system, a tree-structured, self-organizing, artificial neural network was designed. The training time never exceeded 30 seconds for any of the configurations used, which is three to four times faster than most currently used artificial neural network (ANN) architectures.


IEEE Transactions on Biomedical Engineering | 2009

A Novel Concept for a Prosthetic Hand With a Bidirectional Interface: A Feasibility Study

Christian Cipriani; Christian Antfolk; Christian Balkenius; Birgitta Rosén; Göran Lundborg; Maria Chiara Carrozza; Fredrik Sebelius

A conceptually novel prosthesis consisting of a mechatronic hand, an electromyographic classifier, and a tactile display has been developed and evaluated by addressing problems related to controllability in prosthetics: intention extraction, perception, and feeling of ownership. Experiments have been performed, and encouraging results for a young transradial amputee are reported.


Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery | 2010

SmartHand tactile display: A new concept for providing sensory feedback in hand prostheses

Christian Antfolk; Christian Balkenius; Birgitta Rosén; Göran Lundborg; Fredrik Sebelius

Abstract A major drawback with myoelectric prostheses is that they do not provide the user with sensory feedback. Using a new principle for sensory feedback, we did a series of experiments involving 11 healthy subjects. The skin on the volar aspect of the forearm was used as the target area for sensory input. Experiments included discrimination of site of stimuli and pressure levels at a single stimulation point. A tactile display based on digital servomotors with one actuating element for each of the five fingers was used as a stimulator on the forearm. The results show that the participants were able to discriminate between three fingers with an accuracy of 97%, between five fingers with an accuracy of 82%, and between five levels with an accuracy of 79%. The tactile display may prove a helpful tool in providing amputees with sensory feedback from a prosthetic hand by transferring tactile stimuli from the prosthetic hand to the skin at forearm level.


Archive | 1998

Neural Control of a Virtual Prosthesis

Lars Eriksson; Fredrik Sebelius; Christian Balkenius

The abilities of the currently existing hand prostheses are typically limited to opening or closing the hand. This limits the usefulness of the prosthesis considerably compared to the many degrees of freedom in an intact hand. In order to develop more advanced hand prostheses two main problems have to be solved. The first is to develop more advanced mechanical solutions that allows for more degrees of freedom. The second, that we address below, is to devise a way of controlling the additional dexterity of such a prosthesis. Before the second problem is solved, the development of more advanced prostheses will be severely hindered.


Disability and Rehabilitation: Assistive Technology | 2013

Transfer of tactile input from an artificial hand to the forearm: experiments in amputees and able-bodied volunteers.

Christian Antfolk; Christian Cipriani; Maria Chiara Carrozza; Christian Balkenius; Anders Björkman; Göran Lundborg; Birgitta Rosén; Fredrik Sebelius

Purpose: This study explores the possibilities of transferring peripheral tactile stimulations from an artificial hand to the forearm skin. Method: A tactile display applied to the forearm skin was used to transfer tactile input to the forearm from various locations on a hand displayed on a computer screen. Discernment of location, levels of pressure and a combination of the two in simulated functional grips was tested to quantify the participants’ ability to accurately perceive the tactile stimulations presented. Ten participants (5 forearm amputees and 5 able-bodied volunteers) unfamiliar with the equipment participated in the three-stage experiments comprising a learning session with vision, a reinforced learning session without vision and a validation session without vision. Results: The location discernment accuracy was high in both groups (75.2% and 89.6% respectively). The capacity to differentiate between three different levels of pressure was also high (91.7% and 98.1% respectively in the two groups). Recognition of simulated grip was slightly more difficult with the groups scoring 58.7% and 68.0% respectively for accuracy in the validation session. Conclusions: This study demonstrates that it is possible, following a brief training period, to transfer tactile input from an artificial hand to the forearm skin. The level of accuracy was lower for the more complex task, simulated grip recognition, possibly because this represents a more complex task requiring higher order brain functions. These results could form the basis for developing sensory feedback in hand prostheses. Implications for Rehabilitation It is possible, following a brief training period, to transfer tactile input from an artificial hand to the forearm skin. This would be useful to make upper extremity amputees experience their prosthesis in a new way with the addition of sensory feedback

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Christian Cipriani

Sant'Anna School of Advanced Studies

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Maria Chiara Carrozza

Sant'Anna School of Advanced Studies

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Marco Controzzi

Sant'Anna School of Advanced Studies

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