Friedhelm Balkenhohl
Bosch
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Publication
Featured researches published by Friedhelm Balkenhohl.
Zeitschrift für Naturforschung B | 1999
Friedhelm Balkenhohl; Joachim Dr. Paust
(R )-α-Lipoic acid is synthesized in seven steps from the base chemicals methyl acetoacetate or Meldrum’s acid and monomethyl adipate. The key steps are the introduction of the stereogenic center by fermentative or homogeneously catalyzed hydrogenation of 3-oxooctanedioic acid diester to (3S)-3-hydroxyoctanedioic acid diester and its regioselective reduction to (6S)-6 ,8-dihydroxyoctanoic acid ester. The overall yield of (R )-α-lipoic acid, starting from 3-oxooctanedioic acid diester, is 40%.
Journal Fur Praktische Chemie-chemiker-zeitung | 1997
Friedhelm Balkenhohl; Klaus Ditrich; Bernhard Hauer; Wolfgang Ladner
Archive | 1996
Friedhelm Balkenhohl; Klaus Ditrich; Christoph Nübling
Archive | 1994
Friedhelm Balkenhohl; Bernhard Hauer; Wolfgang Ladner; Uwe Pressler; Christoph Nübling
Archive | 1994
Friedhelm Balkenhohl; Bernhard Hauer; Wolfgang Ladner; Uwe Pressler; Christoph Nübling
Archive | 1991
Friedhelm Balkenhohl; Joachim Paust
Archive | 1996
Klaus Ditrich; Friedhelm Balkenhohl; Wolfgang Ladner
Archive | 1993
Klaus Kaiser; Friedhelm Balkenhohl; Joachim Paust
Archive | 1996
Friedhelm Balkenhohl; Klaus Ditrich; Christoph Nübling
Archive | 1995
Friedhelm Balkenhohl; Joachim Paust