G. Canto
Complutense University of Madrid
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by G. Canto.
Pharmacogenomics Journal | 2016
J.A. Cornejo-Garcia; Antonino Romano; Rosa-Maria Guéant-Rodriguez; Abderrahim Oussalah; Natalia Blanca-López; Francesco Gaeta; Tramoy D; Thomas Josse; I Doña; M. J. Torres; G. Canto; Miguel Blanca; Jean-Louis Guéant
Genetic predictors of beta-lactam (BL) allergy are mostly related to Immunoglobulin E (IgE) synthesis and atopy. Despite this context, little attention has been devoted to genes of IgE/FcɛRI pathway, such as galectin-3, a β-galactoside-binding lectin, which binds to IgE. We evaluated the association of LGALS3 polymorphisms with BL allergy in 395 Spanish and 198 Italian cases, compared with 310- and 339-matched controls, respectively. The rs11125 predicted BL allergy with an odds ratio of 4.0 in Spanish population (P<0.0001). This association was replicated with an odds ratio of 5.1 in Italian population (P<0.0001); rs11125 predicted also increased serum level of total IgE in Spanish controls. These data are consistent with the predicted deleterious influence of Gln>His substitution produced by rs11125 on galactose-binding activity of galectin-3. In conclusion, LGALS3 is the strongest genetic predictor of BL allergy reported so far. This association reflects the influence of genes of IgE/FcɛRI pathway in this pathology.
The Journal of Allergy and Clinical Immunology | 2007
M. J. Torres; Natalia Blanca-López; E. Martin; Cristobalina Mayorga; J.L. Rodriguez-Bada; Inmaculada Doña; G. Canto; C. Antunez; J.J. Romero; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2011
Miguel Blanca; Paloma Campo; C. Rondon; Jose Antonio Cornejo; Inmaculada Doña; L. Haggeman; M. J. Torres; Lidia Melendez; J.L. Rodriguez-Bada; G. Canto
/data/revues/00916749/unassign/S0091674914010513/ | 2014
Jean-Louis Guéant; Antonino Romano; J.A. Cornejo-Garcia; Abderrahim Oussalah; Céline Chery; Natalia Blanca-López; Rosa-Maria Guéant-Rodriguez; Francesco Gaeta; Pierre Rouyer; Thomas Josse; G. Canto; F. David Carmona; Lara Bossini-Castillo; Javier Martin; Jose-Julio Laguna; Javier Fernández; Francisco Feo; David A. Ostrov; Pablo Plasencia; Cristobalina Mayorga; M. J. Torres; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2012
M. J. Torres; Inmaculada Doña; Ignacio Garcia; Francisca Gomez; María L. Salas; Natalia Blanca-López; M.D. Caamero; G. Canto; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2012
Inmaculada Doña; Paloma Campo; Marek Sanak; Jose Antonio Cornejo; A. Correa; Natalia Blanca-López; María L. Salas; M. Sanchez; G. Canto; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2012
Natalia Blanca-López; Inmaculada Doña; M. J. Torres; Paloma Campo; C. Rondon; María L. Salas; Ignacio Garcia; G. Canto; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2012
J.A. Cornejo-Garcia; María del Carmen Plaza-Serón; Carlos Flores; Inmaculada Doña; Natalia Blanca-López; L.R. Jagemann; Jose Julio Laguna; Javier Fernández; G. Canto; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2011
L.R. Jagemann; J.A. Cornejo-Garcia; Natalia Blanca-López; Inmaculada Doña; Javier Fernández; Jose Julio Laguna; A. Rosado; R.M. Rodriguez-Gueant; J.L. Gueant; G. Canto; Miguel Blanca
The Journal of Allergy and Clinical Immunology | 2011
M. J. Torres; Francisca Gomez; A. Rosado; Inmaculada Doña; Natalia Blanca-López; Maria Dolores Cañamero; Lidia Melendez; G. Canto; Miguel Blanca
