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Featured researches published by G. Gaffke.


CardioVascular and Interventional Radiology | 2006

Osteoid Osteoma: Experience with Laser- and Radiofrequency-Induced Ablation

Bernhard Gebauer; Per-Ulf Tunn; G. Gaffke; I. Melcher; Roland Felix; C. Stroszczynski

The purpose of this study was to analyze the clinical outcome of osteoid osteoma treated by thermal ablation after drill opening. A total of 17 patients and 20 procedures were included. All patients had typical clinical features (age, pain) and a typical radiograph showing a nidus. In 5 cases, additional histological specimens were acquired. After drill opening of the osteoid osteoma nidus, 12 thermal ablations were induced by laser interstitial thermal therapy (LITT) (9F Power-Laser-Set; Somatex, Germany) and 8 ablations by radiofrequency ablation (RFA) (RITA; StarBurst, USA). Initial clinical success with pain relief has been achieved in all patients after the first ablation. Three patients had an osteoid osteoma recurrence after 3, 9, and 10 months and were successfully re-treated by thermal ablation. No major complication and one minor complication (sensible defect) were recorded. Thermal ablation is a safe and minimally invasive therapy option for osteoid osteoma. Although the groups are too small for a comparative analysis, we determined no difference between laser- and radiofrequency-induced ablation in clinical outcome after ablation.


CardioVascular and Interventional Radiology | 2006

Use of Semiflexible Applicators for Radiofrequency Ablation of Liver Tumors

G. Gaffke; Bernhard Gebauer; F.D. Knollmann; T. Helmberger; J Ricke; H. Oettle; Roland Felix; C. Stroszczynski

PurposeTo evaluate the feasibility and potential advantages of the radiofrequency ablation of liver tumors using new MRI-compatible semiflexible applicators in a closed-bore high-field MRI scanner.MethodsWe treated 8 patients with 12 malignant liver tumors of different origin (5 colorectal carcinoma, 2 cholangiocellular carcinoma, 1 breast cancer) under MRI guidance. Radiofrequency ablation (RFA) was performed using 5 cm Rita Starburst Semi-Flex applicators (Rita Medical Systems, Milwaukee, WI, USA) which are suitable for MR- and CT-guided interventions and a 150 W RF generator. All interventions were performed in a closed-bore 1.5 T high-field MRI scanner for MRI-guided RFA using fast T1-weighted gradient echo sequences and T2-weighted ultra-turbo spin echo sequences. Control and follow-up MRI examinations were performed on the next day, at 6 weeks, and every 3 months after RFA. Control MRI were performed as double-contrast MRI examinations (enhancement with iron oxide and gadopentetate dimeglumine). All interventions were performed with the patient under local anesthesia and analgo-sedation.ResultsThe mean diameter of the treated hepatic tumors was 2.4 cm (±0.6 cm, range 1.0–3.2 cm). The mean diameter of induced necrosis was 3.1 cm (±0.4 cm). We achieved complete ablation in all patients. Follow-up examinations over a duration of 7 months (±1.3 months, range 4–9 month) showed a local control rate of 100% in this group of patients. All interventions were performed without major complications; only 2 subcapsular hematomas were documented.ConclusionRFA of liver tumors using semiflexible applicators in closed-bore 1.5 T scanner systems is feasible. These applicators might simplify the RFA of liver tumors under MRI control. The stiff distal part of the applicator facilitates its repositioning.


European Journal of Radiology | 2002

Tumour of the diaphragm mimicking liver lesion

Ralf Puls; Roland Kreissig; Norbert Hosten; G. Gaffke; C. Stroszczynski; Roland Felix

Tumours of the diaphragm bordering the liver may impose diagnostic difficulties. We report the case of a 46-year-old patient diagnosed with a tumour of the liver based on ultrasound and CT. MRI of the liver depicted a tumour growing from the chest wall towards the liver. Surgery revealed the rare entity of a malignant fibrous histiocytoma of the diaphragm.


European Radiology | 2005

Follow-up of gastro-intestinal stromal tumours (GIST) during treatment with imatinib mesylate by abdominal MRI

C. Stroszczynski; Dominik Jost; Peter Reichardt; Petra Chmelik; G. Gaffke; Albrecht Kretzschmar; Ulrike Schneider; Roland Felix; Peter Hohenberger


Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren | 2005

Potenzial der MRT für die Radiofrequenzablation von Lebertumoren

G. Gaffke; Bernhard Gebauer; M. Gnauck; Friedrich D. Knollmann; T. Helmberger; J. Ricke; Helmut Oettle; Roland Felix; C. Stroszczynski


Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren | 2003

Differenzierung von Leberläsionen mit SPIO-gestützten T1-w und T2-w MRT-Aufnahmen: Eine ROC-Analyse

C. Stroszczynski; G. Gaffke; S. Gretschel; Rambow A; Jost D; Schlecht I; Schneider U; Schicke B; Hohenberger P; Bernhard Gebauer; Roland Felix


Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren | 2003

Morphologie gastrointestinaler Stromatumoren im fortgeschrittenen Stadium der Erkrankung: Ausgangsbefunde vor Chemotherapie mit Imatinib

Jost D; C. Stroszczynski; P. Chmelik; G. Gaffke; Schlecht I; Pink D; Reichardt P; Schneider U; Hohenberger P; R. Felix


Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren | 2005

CT-gesteuerte Resektion pulmonaler Metastasen

G. Gaffke; C. Stroszczynski; Beate Rau; U. Liebeskind; M. Hünerbein; S. Bayraktar; Peter M. Schlag; R. Felix


Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren | 2003

Flexible applicator systems for radiofrequency ablation (RFA) of hepatic tumors

Bernhard Gebauer; G. Gaffke; M. Hünerbein; R. Felix; C. Stroszczynski


Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren | 2001

[Laser-induced thermotherapy (LITT). Use of round and pointed laser applicator systems--initial results].

Ralf Puls; Norbert Hosten; C. Stroszczynski; Kreissig R; G. Gaffke; R. Felix

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R. Felix

Free University of Berlin

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Ralf Puls

University of Greifswald

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