G. Godiris-Petit

Surgical management of sporadic medullary thyroid cancer

Inherited and sporadic medullary thyroid cancer (MTC) is a rare carcinoma. Sporadic MTCs represent 70% of cases. Diagnosis is currently made with the routine use of serum calcitonin (CT) measurements to screen patients with nodular thyroid disease. Surgery is the only curative treatment of MTC and since cervical lymph nodes metastases are frequent and can occur at an early stage, a standardized lymph node dissection should be associated to total thyroidectomy. However, the extent of lymphadenectomy remains debated. Prognosis of MTC is related to both the stage of the disease and the extent of initial surgery. When tumor remnants persist after surgery, there are very few therapeutic alternatives, and these are generally of limited curative value.

Ischaemic colitis: Indications, extent, and results of standardized emergency surgery

BACKGROUND Acute ischaemic colitis can occur postoperatively, mainly after aortic surgery, or spontaneously. Surgical treatment is debated. Study aim was to describe factors related to ischaemic colitis severity, determine if postoperative and spontaneous ischaemic colitis share similar outcomes, and evaluate results of standardized management. METHODS 191 consecutive cases of ischaemic colitis observed from 1997 to 2012 were retrospectively analyzed: 119 (62%) after surgery and 72 (38%) spontaneous. Colon resection was performed for endoscopic type 2 colitis with multiple organ failure, and for every type 3. Types 1 and 2 without multiple organ failure were managed nonoperatively. RESULTS Seventeen patients (9%) were managed nonoperatively, without mortality. Mortality rate after resection was 48% (84/174), within 9 days (range, 0-152). Multivariate analysis found 2 independent factors associated with postoperative death: age≥75 years and multiple organ failure. The context in which ischaemic colitis occurred was not a risk factor for mortality. Mortality rates were 51% for final type 3 (66% with multiple organ failure, 17% without), 53% for final type 2 with multiple organ failure, and 0% for type 1 or type 2 without multiple organ failure. CONCLUSION An aggressive surgical approach in patients with ischaemic colitis seems justified in patients with multiple organ failure and findings of severe form of ischaemia at endoscopy.

Splénectomie partielle par laparoscopie et ultracision©: À propos de deux cas

For the extirpation of a benign splenic cyst, partial splenectomy is an appropriate approach, since there is significant long-term morbidity following total splenectomy. We report two cases of laparoscopic partial splenectomy for benign splenic cyst. The use of the harmonic scalpel along with segmental ligation of the splenic pedicle allowed the completion of these interventions with minimal blood loss.Resume En cas de tumeur benigne splenique, il semble licite de proposer une splenectomie partielle ; la splenectomie totale entrainant une morbidite propre a long terme. Nous rapportons ici deux cas de splenectomie partielle par laparoscopie pour lesion kystique splenique. L’utilisation de l’ultracision©, associee au clampage segmentaire du pedicule splenique, a permis de realiser cette intervention avec des pertes sanguines minimes.

Laparoscopic resection of interaortocaval paraganglioma in left lateral decubitus (with video)

Please cite this article in press as: Najah H, et al. Laparoscopic resection of interaortocaval paraganglioma in left lateral decubitus (with video). Journal of Visceral Surgery (2017), http://dx.doi.org/10.1016/j.jviscsurg.2017.06.012 de l’Hôpital, 75013 Paris, France c Service d’endocrinologie et métabolisme, Institut E3M, Hôpital de la Pitié-Salpêtrière, Paris VI, Pierre-et-Marie-Curie-Sorbonne universités, 47—83, boulevard de l’Hôpital, 75013 Paris, France

Management of traumatic small bowel injury by mechanical anastomosis "without resection" during damage control laparotomy.

Penetrating or blunt abdominal injury can produce small bowel injuries that are sometimes complex and difficult to repair. Management of these injuries requires a safe, quick and reproducible technique. Surgery should take into consideration not only the injury itself, but also patient status, the eventual presence of associated injuries, shock, hypothermia or metabolic acidosis [1]. For a stable, non-shocked patient, presenting with a simple small linear intestinal wound with clear and well-vascularized edges, simple suture closure, with either a continuous or interrupted sutures using slowly absorbable or non-absorbable material can be performed. Conversely for high-risk patients with complex gastro-intestinal wounds, or when the wound edges are torn, and damaged, we propose performance of a side-to-side stapled anastomosis ‘‘without mesenteric resection or ligation’’. This procedure is simple to perform, simple to learn and is easily reproducible. Morbidity is similar to that of manual repair and allows performance of the anastomosis on healthy tissues [2,3].

Article originalŒsophagectomie mini-invasive : évaluation prospective de la gastrolyse cœlioscopiqueMinimally invasive esophagectomy: prospective evaluation of laparoscopic gastric mobilization

OBJECTIVE Esophagectomy carries high morbidity, mainly due to respiratory complications. In digestive surgery, postoperative outcome is generally improved by minimally invasive surgery. A prospective study was conducted to evaluate feasibility and postoperative outcome of minimally invasive esophagectomy (MIE). METHODS From July 2001 to June 2004, 20 patients underwent esophagectomy with laparoscopic gastric mobilization (LGM) for squamous cell carcinoma (N=11), adenocarcinoma (N=7), Barretts esophagus with high-grade dysplasia (N=1), and long peptic stricture (N=1). Tumours (N=19) were located on the cardia (N=5), on the lower third of the oesophagus (N=10), on the median third (N=3), and on the upper third (N=1). Following LGM, transthoracic (N=19) or transhiatal (N=1) oesophagectomy was performed. RESULTS Complete LGM was achieved in all cases. Mean operative time for LGM was 197+/-48 minutes. In the 19 patients operated for tumours, 18 underwent R0 resection. Eleven patients (55%) developed postoperative complications, mainly (30%) respiratory. Intrathoracic anastomotic leakage occurred in 2 patients, with favourable outcome. Pylorospasm (N=1) was the only intraabdominal complication. One patient died (5%). CONCLUSION Esophagectomy with LGM is feasible with few specific complications. However, no decrease in morbidity could be observed with this technique. Further studies are required to evaluate if thoracoscopy could improve the postoperative course after LGM and to validate oncologic safety of MIE.

Œsophagectomie mini-invasive : évaluation prospective de la gastrolyse cœlioscopique

OBJECTIVE Esophagectomy carries high morbidity, mainly due to respiratory complications. In digestive surgery, postoperative outcome is generally improved by minimally invasive surgery. A prospective study was conducted to evaluate feasibility and postoperative outcome of minimally invasive esophagectomy (MIE). METHODS From July 2001 to June 2004, 20 patients underwent esophagectomy with laparoscopic gastric mobilization (LGM) for squamous cell carcinoma (N=11), adenocarcinoma (N=7), Barretts esophagus with high-grade dysplasia (N=1), and long peptic stricture (N=1). Tumours (N=19) were located on the cardia (N=5), on the lower third of the oesophagus (N=10), on the median third (N=3), and on the upper third (N=1). Following LGM, transthoracic (N=19) or transhiatal (N=1) oesophagectomy was performed. RESULTS Complete LGM was achieved in all cases. Mean operative time for LGM was 197+/-48 minutes. In the 19 patients operated for tumours, 18 underwent R0 resection. Eleven patients (55%) developed postoperative complications, mainly (30%) respiratory. Intrathoracic anastomotic leakage occurred in 2 patients, with favourable outcome. Pylorospasm (N=1) was the only intraabdominal complication. One patient died (5%). CONCLUSION Esophagectomy with LGM is feasible with few specific complications. However, no decrease in morbidity could be observed with this technique. Further studies are required to evaluate if thoracoscopy could improve the postoperative course after LGM and to validate oncologic safety of MIE.

[Minimally invasive esophagectomy: prospective evaluation of laparoscopic gastric mobilization].

OBJECTIVE Esophagectomy carries high morbidity, mainly due to respiratory complications. In digestive surgery, postoperative outcome is generally improved by minimally invasive surgery. A prospective study was conducted to evaluate feasibility and postoperative outcome of minimally invasive esophagectomy (MIE). METHODS From July 2001 to June 2004, 20 patients underwent esophagectomy with laparoscopic gastric mobilization (LGM) for squamous cell carcinoma (N=11), adenocarcinoma (N=7), Barretts esophagus with high-grade dysplasia (N=1), and long peptic stricture (N=1). Tumours (N=19) were located on the cardia (N=5), on the lower third of the oesophagus (N=10), on the median third (N=3), and on the upper third (N=1). Following LGM, transthoracic (N=19) or transhiatal (N=1) oesophagectomy was performed. RESULTS Complete LGM was achieved in all cases. Mean operative time for LGM was 197+/-48 minutes. In the 19 patients operated for tumours, 18 underwent R0 resection. Eleven patients (55%) developed postoperative complications, mainly (30%) respiratory. Intrathoracic anastomotic leakage occurred in 2 patients, with favourable outcome. Pylorospasm (N=1) was the only intraabdominal complication. One patient died (5%). CONCLUSION Esophagectomy with LGM is feasible with few specific complications. However, no decrease in morbidity could be observed with this technique. Further studies are required to evaluate if thoracoscopy could improve the postoperative course after LGM and to validate oncologic safety of MIE.