G. Lin

The effect of neural embryonic stem cell therapy in a rat model of cavernosal nerve injury

To isolate embryonic stem cells that have differentiated along the neuronal cell line, and to assess whether injecting these neural stem cells into the corpus cavernosum influences cavernosal nerve regeneration and functional status.

The effect of vascular endothelial growth factor and brain-derived neurotrophic factor on cavernosal nerve regeneration in a nerve-crush rat model

To test the hypothesis that an intracavernosal injection with brain‐derived neurotrophin factor (BDNF) and vascular endothelial growth factor (VEGF) can facilitate nerve regeneration and recovery of erectile function after cavernosal nerve injury.

Intracavernosal injection of vascular endothelial growth factor induces nitric oxide synthase isoforms

Objective To identify genes that are affected by vascular endothelial growth factor (VEGF), as an intracavernosal injection with VEGF improved the recovery of erectile function in a rat model of arteriogenic impotence, specifically examining the three nitric oxide synthase (NOS) genes, nNOS, eNOS, and iNOS.

Neurotrophic effects of vascular endothelial growth factor and neurotrophins on cultured major pelvic ganglia

In a study by researchers from San Francisco and Taiwan, a ganglial culture system is used to screen various growth factors. The aim was to assess these growth factors as possible therapeutic agents for pelvic floors nerve injuries. They found that vascular endothelial growth factor causes a marked neurotrophic effect.

Wogonin suppresses cellular proliferation and expression of monocyte chemoattractant protein 1 in Peyronie's plaque-derived cells

The group of authors from San Francisco and Shanghai describe their investigation of wogonin, a flavonoid extracted from a naturally occurring root, which has been used in traditional Chinese medicine to treat inflammatory diseases. Here they study the mechanisms for its anti‐inflammatory properties.