G. R. Srinivasa

The synthesis of azo compounds from nitro compounds using lead and triethylammonium formate

Aromatic nitro compounds were reduced to the corresponding symmetrically substituted azo compounds using lead as catalyst and triethylammonium formate as hydrogen donor. Various azo compounds containing additional reducible substituents including halogens, nitrile, acid, phenol, ester, methoxy functions, etc, have been synthesized in a single step by the use of this reagent. The conversion is reasonably fast, clean, high yielding and occurs at room temperature in methanol.

Convenient, Cost‐Effective, and Mild Method for the N‐Acetylation of Anilines and Secondary Amines

Abstract An efficient, cost‐effective, and mild method for the N‐acetylation of anilines and secondary amines with ammonium acetate in acetic acid media at reflux temperature in good yield is described.

Lead-Catalyzed Synthesis of Azo Compounds by Ammonium Acetate Reduction of Aromatic Nitro Compounds

Abstract Lead/ammonium acetate is a convenient reagent for the reduction of aromatic nitro compounds to the corresponding symmetrically substituted azo compounds. Various azo compounds containing additional reducible substituents such as halogen, nitrile, acid, phenol, ester, methoxy, etc., functions have been synthesized in a single step by the use of this reagent. The conversion is reasonably fast, clean, high yielding and occurs at room temperature in methanol.

Conventional and Microwave Assisted Hydrogenolysis Using Zinc and Ammonium Formate

Abstract The selective deprotection of several N‐Bzl amino derivatives to the corresponding amines and the removal of S‐Bzl and O‐Bzl groups from the protected amino acids with ammonium formate and commercial zinc dust are reported. Many other reducible or hydrogenolysable substituents such as halogens, methoxy, phenol, ester, acid, ethene, and Boc groups are unaffected.

Reductive Cleavage of Azo Compounds by Zinc and Ammonium Chloride

Abstract Azo compounds are reduced to corresponding anilines with zinc dust in the presence of ammonium chloride in methanol at room temperature.

Transfer Hydrogenation of Aromatic Nitro Compounds Using Polymer‐Supported Formate and Pd‐C

Abstract Transfer hydrogenation of aromatic nitro compounds using recyclable polymer‐supported formate as hydrogen donor and Pd‐C as a catalyst produces corresponding amines in excellent yields (90–98%).

Facile Synthesis of Azo Compounds from Aromatic Nitro Compounds using Magnesium and Triethylammonium Formate

Magnesium/triethylammonium formate is a convenient reagent for the reduction of aromatic nitro compounds to corresponding symmetrically substituted azo compounds. Various azo compounds containing additional reducible substituents, including halogen, nitrile, acid, phenol, ester, and methoxy functions, have been synthesized in a single step by the use of this reagent. The conversion is reasonably fast, clean, high yielding, and occurs at room temperature in methanol.

Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer-Supported Formate and Magnesium

Aromatic nitro compounds were chemoselectively reduced to the corresponding amines using recyclable polymer-supported formate as a hydrogen donor in the presence of low-cost magnesium powder at room temperature. Use of the immobilized hydrogen donor affords the product amine in excellent yield (90–97%) without the need for any chromatographic purification steps. This method was found to be highly facile with selectivity over several other functional groups, such as halogen, alkene, nitrile, carbonyl, ester, amide, methoxy, phenol, and hydroxyl groups.

Catalytic transfer hydrogenation of imines to secondary amines using inexpensive commercial zinc dust and ammonium formate

A simple protocol for the chemo-selective reduction of imines to the corresponding secondary amines in good yield using inexpensive commercial zinc dust and ammonium formate in methanol at ambient temperature and pressure is described.

Clean and Efficient Hydrogenative Cleavage of Azo Compounds Using Polymer‐Supported Formate and Zinc

Abstract Azo compounds, both symmetric and asymmetric, were chemoselectively reduced to the corresponding amine(s) using recyclable polymer‐supported formate as a hydrogen donor in the presence of zinc at room temperature.