Gábor Bodor

Role of heart transplantation in pediatric heart surgery. The first successful pediatric heart transplantation in Hungary

7-year-old boy, who underwent aortic valve replacement two years previously, suffered from idiopathic dilated cardiomyopathy. Because of poor condition (NYHA-IV), heart transplantation was performed on 18th October 2007. It was the first pediatric heart transplantation in Hungary. It was an uneventful early postoperative period, 6 months after the operation he is doing well, no biopsy-proven and tissue Doppler echocardiography (TDI-derived velocities measurement) rejection was detected. The immunosuppression was based on triple-drug therapy (tacrolimus+mycophenolate mofetil+corticosteroid) with use of induction therapy with interleukin-2 receptor blocker (basiliximab).

Sikeres szívátültetés veleszületett szívhiba korrekciós szívmutéte után. Sebésztechnikai problémák

Heart transplantation was performed in a 17-year old boy with severe left ventricular failure. Previously a congenital heart disease, tetralogy of Fallot was reconstructed in one and half years old of age. Authors present the different surgical problems complicated this procedure. In Hungary this is the first heart transplantation after a corrective surgical procedure of a complex congenital heart disease.

Sikeres szívátültetés veleszületett szívhiba korrekciós szívműtéte után. Sebésztechnikai problémák@@@Heart transplantation after corrective surgery of a congenital heart disease. Surgical technical problems

Heart transplantation was performed in a 17-year old boy with severe left ventricular failure. Previously a congenital heart disease, tetralogy of Fallot was reconstructed in one and half years old of age. Authors present the different surgical problems complicated this procedure. In Hungary this is the first heart transplantation after a corrective surgical procedure of a complex congenital heart disease.

Heart transplantation after corrective surgery of a congenital heart disease. Surgical technical problems

Heart transplantation was performed in a 17-year old boy with severe left ventricular failure. Previously a congenital heart disease, tetralogy of Fallot was reconstructed in one and half years old of age. Authors present the different surgical problems complicated this procedure. In Hungary this is the first heart transplantation after a corrective surgical procedure of a complex congenital heart disease.

Surgical management with mitral valve replacement in young infants with congenital mitral valve diseases and complete atrioventricular septal defect

OBJECTIVES The mechanical valve replacement may be the only option if the failing mitral valve cannot be repaired in complete AV septal defect (CAVSD), or congenital mitral valve stenosis and regurgitation in infants. In young infants the small mitral annulus-prosthesis mismatch is a big problem. AIM To assess the possibility of the left AV orifice repair and the necessity of mechanical valve replacement in CAVSD in young infants. METHODS Single center, retrospective study of 82 infants (13 pts under 3 months) who underwent complete repair of CAVSD between 2001 and 2007. Mechanical (bileaflet) valve replacement was required in 7 pts (5 weeks-7 months, 3.5-5 kg). The time interval between the two operations was 0-7 days, but the smallest baby spent 38 days in the intensive care unit waiting for increasing of his mitral annulus size from 11 to 15 mm. (Types of implanted valves: 2 Carbomedics 16 mm, 3 ATS 16 mm, 1 Sorin 17 mm, 1 Sorin 19 mm.) ATS 16 mm valves were implanted in 2 infants each with congenital mitral valve stenosis and regurgitation. RESULTS Early mortality (30 days) was 0, but 2 pts died in sepsis on the 46th and 71st postoperative day, respectively. In the follow-up period of 1-6 (mean 3) years 1 child (18 months later) needed reoperation (pannus removal), now all pts are doing well. Anticoagulation therapy was difficult in some cases without complication. CONCLUSIONS The surgical repair of congenital mitral valve diseases and CAVSD can be performed successfully in very young infants. If the anatomic characteristics of the mitral valve is not suitable for repair, only mechanical mitral valve replacement can be performed successfully even in sometimes hopeless situation (one of our pts of 3.5 kg weight, is the smallest baby mentioned in the literature). Our early and mid-time results are good, but the re-replacement will be an unavoidable problem in the future.

A szívtranszplantáció helye a gyermekszívsebészetben. Az első sikeres gyermekszív-átültetés Magyarországon@@@The role of heart transplantation in pediatric heart surgery. The first pediatric heart transplantation in Hungary

7-year-old boy, who underwent aortic valve replacement two years previously, suffered from idiopathic dilated cardiomyopathy. Because of poor condition (NYHA-IV), heart transplantation was performed on 18th October 2007. It was the first pediatric heart transplantation in Hungary. It was an uneventful early postoperative period, 6 months after the operation he is doing well, no biopsy-proven and tissue Doppler echocardiography (TDI-derived velocities measurement) rejection was detected. The immunosuppression was based on triple-drug therapy (tacrolimus+mycophenolate mofetil+corticosteroid) with use of induction therapy with interleukin-2 receptor blocker (basiliximab).

A szívtranszplantáció helye a gyermekszívsebészetben. Az elso sikeres gyermekszív-átültetés Magyarországon

7-year-old boy, who underwent aortic valve replacement two years previously, suffered from idiopathic dilated cardiomyopathy. Because of poor condition (NYHA-IV), heart transplantation was performed on 18th October 2007. It was the first pediatric heart transplantation in Hungary. It was an uneventful early postoperative period, 6 months after the operation he is doing well, no biopsy-proven and tissue Doppler echocardiography (TDI-derived velocities measurement) rejection was detected. The immunosuppression was based on triple-drug therapy (tacrolimus+mycophenolate mofetil+corticosteroid) with use of induction therapy with interleukin-2 receptor blocker (basiliximab).

The role of heart transplantation in pediatric heart surgery. The first pediatric heart transplantation in Hungary

7-year-old boy, who underwent aortic valve replacement two years previously, suffered from idiopathic dilated cardiomyopathy. Because of poor condition (NYHA-IV), heart transplantation was performed on 18th October 2007. It was the first pediatric heart transplantation in Hungary. It was an uneventful early postoperative period, 6 months after the operation he is doing well, no biopsy-proven and tissue Doppler echocardiography (TDI-derived velocities measurement) rejection was detected. The immunosuppression was based on triple-drug therapy (tacrolimus+mycophenolate mofetil+corticosteroid) with use of induction therapy with interleukin-2 receptor blocker (basiliximab).