Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Gabriela Sentena Severino is active.

Publication


Featured researches published by Gabriela Sentena Severino.


Physiology & Behavior | 2004

Effects of neonatal handling on the behavior and prolactin stress response in male and female rats at various ages and estrous cycle phases of females

Gabriela Sentena Severino; Isabel Amaral Martins Fossati; Maristela J. Padoin; Cármen Marilei Gomes; Luciano Trevizan; Gilberto Luiz Sanvitto; Celso Rodrigues Franci; Janete A. Anselmo-Franci; Aldo Bolten Lucion

Neonatal handling induces behavioral and hormonal changes, characterized by reduced fear in novel environments, and lesser elevation and faster return to basal levels of plasma corticosterone, prolactin and adrenaline, in response to stressors in adulthood. The present study aimed to analyze the effects of neonatal handling from Days 1 to 10 postnatal on prolactin response to ether stress in male and female rats at three life periods: neonatal, peripubertal and adulthood. Moreover, adult females were tested in two different phases of the estrous cycle, i.e., diestrus and estrus. In another set of experiments, the behavior of peripubertal and adult males and females in estrus and diestrus was analyzed in the elevated plus maze test. Pups were either handled for 1 min (handled group) or left undisturbed (nonhandled group) during the first 10 days after delivery. In adults, in the handled females in diestrus, stress induced a lesser increase in plasma prolactin compared with nonhandled ones, as in males. However, in estrus, handled females showed no difference in the prolactin response to stress. In the elevated plus maze, handled females in diestrus, but not in estrus, showed higher locomotor activity compared with nonhandled ones. Peripubertal male and female rats handled during the neonatal period showed no difference in behavior in the elevated plus maze compared with nonhandled animals. Early-life stimulation can induce long-lasting behavioral and stress-related hormonal changes, but they are not stable throughout life and phases of the estrous cycle.


Brazilian Journal of Medical and Biological Research | 2001

Neonatal handling and the expression of immunoreactivity to tyrosine hydroxylase in the hypothalamus of adult male rats

Erica do Espirito Santo Hermel; Gabriela Sentena Severino; Ana Lúcia Cecconello; Francine Martins Pereira; Gilberto Luiz Sanvitto; Aldo Bolten Lucion

Neonatal handling has long-lasting effects on behavior and stress reactivity. The purpose of the present study was to investigate the effect of neonatal handling on the number of dopaminergic neurons in the hypothalamic nuclei of adult male rats as part of a series of studies that could explain the long-lasting effects of neonatal stimulation. Two groups of Wistar rats were studied: nonhandled (pups were left undisturbed, control) and handled (pups were handled for 1 min once a day during the first 10 days of life). At 75-80 days, the males were anesthetized and the brains were processed for immunohistochemistry. An anti-tyrosine hydroxylase antibody and the avidin-biotin-peroxidase method were used. Tyrosine hydroxylase-immunoreactive (TH-IR) neurons were counted bilaterally in the arcuate, paraventricular and periventricular nuclei of the hypothalamus in 30-microm sections at 120-microm intervals. Neonatal handling did not change the number of TH-IR neurons in the arcuate (1021 +/- 206, N = 6; 1020 +/- 150, N = 6; nonhandled and handled, respectively), paraventricular (584 +/- 85, N = 8; 682 +/- 62, N = 9) or periventricular (743 +/- 118, N = 7; 990 +/- 158, N = 7) nuclei of the hypothalamus. The absence of an effect on the number of dopaminergic cells in the hypothalamus indicates that the reduction in the amount of neurons induced by neonatal handling, as shown by other studies, is not a general phenomenon in the brain.


Archive | 2006

UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL INSTITUTO DE CIÊNCIAS BÁSICAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS BIOLÓGICAS: FISIOLOGIA MANIPULAÇÃO NEONATAL E ESTADO HORMONAL: EFEITOS COMPORTAMENTAIS E RESPOSTAS NEUROENDÓCRINAS AO ESTRESSE EM RATOS MACHOS E FÊMEAS ADULTOS

Gabriela Sentena Severino; Aldo Bolten Lucion


Archive | 2004

Manipulação neonatal e atividade noradrenérgica no núcleo paraventricular do hipotálamo em ratas adultas submetidas a estresse

Mariana Benetti Torres; Gabriela Sentena Severino; Gisele Vieira Rodovalho; Raphael Escorsim Szawka; Janete Aparecida Anselmo Franci; Celso Rodrigues Franci


Archive | 2003

Manipulação neonatal reduz a resposta da prolactina ao estresse por contenção em ratas adultas

Mariana Benetti Torres; Gabriela Sentena Severino; Tatiane Sabriela Cagol; Janete Aparecida Anselmo Franci; Celso Rodrigues Franci; Gilberto Luiz Sanvitto


Archive | 2002

Efeito da estimulação neonatal sobre a concentração plasmática de estradiol na manhã do estro e diestro II em ratas submetidas ao estresse por éter

Ana Lúcia Cecconello; Gabriela Sentena Severino; Aldo Bolten Lucion; Gilberto Luiz Sanvitto


Archive | 1998

Papel da mãe sobre comportamentos de ratas pré-púberes e adultas submetidas a estresse neonatal.

Gabriela Sentena Severino; Maristela J. Padoin


Archive | 1997

Imunohistoquímica do acth em ratos neonatais submetidos a estresse

Lígia M. Barbosa Coutinho; Maristela J. Padoin; Luciana P. Cadore; Cláudia E. de Aguiar; Gabriela Sentena Severino


Archive | 1996

Ciclo reprodutivo de Liolaemus wiegmanni (Duméril et Bibron, 1837), no Rio Grande do Sul (sauria-tropiduridae)

Gabriela Sentena Severino; Laura Verrastro Viñas; Erica do Espirito Santo Hermel


Archive | 1996

Dimorfismo sexual em Liolaemus wiejmanni (Duméril et Bibron, 1837), Sauria-tropiduridae

Erica do Espirito Santo Hermel; Laura Verrastro Viñas; Gabriela Sentena Severino

Collaboration


Dive into the Gabriela Sentena Severino's collaboration.

Top Co-Authors

Avatar

Aldo Bolten Lucion

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar

Gilberto Luiz Sanvitto

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Erica do Espirito Santo Hermel

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar

Maristela J. Padoin

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar

Ana Lúcia Cecconello

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Cármen Marilei Gomes

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar

Francine Martins Pereira

Universidade Federal do Rio Grande do Sul

View shared research outputs
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge