Gaetan Touyer

Novel radioactive estradienes labelled with iodine

Novel radioactive estradienes labelled with iodine of the formula ##STR1## in the form of their syn or anti isomers or mixtures thereof wherein the wavy line indicates anti or syn position, R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 1 to 12 carbon atoms and R1 is the residue of an amino acid R1 NH2 possessing an iodine acceptor group or a derivative thereof labelled with iodine 125 or 131 and their preparation and novel intermediates, antigens prepared from the compounds of formula I and bovine seric albumin or human seric albumin and their preparation and their use for the preparation of antibodies.

Radioactive stilbene derivatives in radioimmunoassay

Novel radioactive stilbene derivatives marked with iodine 125 or 131 of the formula ##STR1## wherein each A and B are both hydrogen or together form a double bond and R is the remainder of amino acid of the formula R--NH2 or a derivative thereof possessing an iodine acceptor group and marked with iodine 125 or 131 and their preparation and antigens obtained therefrom and a process for preparing said antigens.

Novel radioactive estratrienes

Novel radioactive DELTA 4,9,11-estratrienes marked with iodine 125 or 131 having the formula I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 2 to 12 carbon atoms, R1 is the reminder of an amino acid of the formula R1NH2 or a derivative thereof being marked with iodine 125 or 131 and the wavy lines indicate the -OR is in the alpha - or beta -position and the oximido group is in the syn or anti position, a process and intermediates for their preparation, antigens prepared therefrom and use thereof to prepare antibodies.