Gan-Peng Li

Two new phenylpropanoids from Swertia atroviolacea and their anti-5α-reductase activity

Abstract Two new phenylpropanoids (1–2), together with two known lignans (3–4), were isolated from whole herb of Swertia atroviolacea. The structures of the new metabolites were established on the basis of detailed spectroscopic analysis. Compounds 1 and 2 were evaluated for their anti-5α-reductase activity. The results revealed that 1 and 2 showed weak activity with reductase inhibitions of 45.6 ± 2.8% and 38.4 ± 2.5%, respectively.

Two new biphenyls from the stems of Garcinia tetralata

Abstract Two new biphenyls (1 and 2) and three known xanthones (3–5) were isolated from the ethanol extract of the stems of Garcinia tetralata. Structural elucidations of 1–2 were elucidated by spectroscopic methods including extensive 1D- and 2D-nuclear magnetic resonance spectroscopy techniques. Compounds 1–2 showed anti-rotavirus activities with SI above 10.

Four New Diterpene Glucosides from Perovskia atriplicifolia

Four new diterpene glucosides, namely perovskiaditerpenosides A – D (1 – 4), were isolated from the BuOH extract of Perovskia atriplicifolia. Their structures were well elucidated by chemical methods and comprehensive spectroscopic analyses including MS, IR, and NMR (1D and 2D). The newly isolated compounds were screened for their cytotoxic activity against HepG2, NB4, HeLa, K562, MCF7, PC3, and HL60. The obtained results indicated that the new compounds possessed considerable cytotoxic activity.