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Dive into the research topics where Ganesh V. Kamath is active.

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Featured researches published by Ganesh V. Kamath.


American Journal of Sports Medicine | 2011

Revision Anterior Cruciate Ligament Reconstruction

Ganesh V. Kamath; John Redfern; Patrick E. Greis; Robert T. Burks

Revision reconstruction of the anterior cruciate ligament (ACL) introduces several diagnostic and technical challenges in comparison with primary ACL reconstruction. With the increasing numbers of original reconstructions combined with the continued expectation of high-level athletic participation, revision ACL reconstruction is likely to become more frequent. The purpose of this article was to summarize the causes of failure and the evaluation of the patient with recurrent instability. A review of the literature regarding results after revision ACL reconstruction was performed to assist in the decision-making process and patient counseling. Good results can be obtained in terms of functional stability after revision reconstruction, but chondral and meniscal injury as well as unrecognized associated pathologic instability may play a role in diminished outcomes. In addition, a wide variety of surgical techniques are reviewed to address problems associated with tunnel malposition, widening, and pre-existing hardware.


Spine | 2006

Selective Posterior Thoracic Fusions for Adolescent Idiopathic Scoliosis: Comparison of Hooks versus Pedicle Screws

Matthew B. Dobbs; Lawrence G. Lenke; Yongjung J. Kim; Ganesh V. Kamath; Michael W. Peelle; Keith H. Bridwell

Study Design. A retrospective review of adolescent idiopathic scoliosis (AIS) patients with major thoracic-compensatory lumbar C modifier curves treated with a selective posterior fusion using an all-hook construct versus pedicle screw construct. Objectives. To compare the clinical and radiographic results of selective posterior thoracic fusion using hooks versus pedicle screws in patients with major thoracic-compensatory lumbar C modifier AIS curves. Summary of Background Data. Although spontaneous lumbar curve correction often occurs following a selective thoracic spinal fusion, there are few reports that focus on selective posterior thoracic spinal fusion in the presence of a lumbar C modifier curve. Methods. Sixty-six consecutive patients with major thoracic-compensatory lumbar C modifier AIS curves underwent selective posterior thoracic fusion to T12 or L1 at a single institution (1987–2001). Hooks were used for instrumentation in 32 patients and pedicle screws were used in 34 patients. Patients were evaluated at a minimum 2-year follow-up. To test for differences between groups analysis of covariance (ANCOVA) was used. Results. There was no statistical difference between the preoperative thoracic and lumbar Cobb values for the hook group versus the pedicle screw group. The amount of correction obtained surgically of the thoracic Cobb and the amount of spontaneous lumbar Cobb correction were significantly greater in the pedicle screw group (P < 0.001). The incidence of postoperative coronal decompensation, with a greater than 20 mm shift to the left of the C7 plumbline, was higher in the hook group (13 patients) as compared with the pedicle screw Group 4 patients (P < 0.005). There were no complications or reoperations in either group. Conclusion. Selective thoracic fusion of main thoracic-compensatory lumbar C modifier AIS curves with pedicle screws allowed for better thoracic correction and less postoperative coronal decompensation than seen with hooks.


American Journal of Sports Medicine | 2014

Effect of Graft Choice on the Outcome of Revision Anterior Cruciate Ligament Reconstruction in the Multicenter ACL Revision Study (MARS) Cohort

Rick W. Wright; Laura J. Huston; Amanda K. Haas; Kurt P. Spindler; Samuel K. Nwosu; Christina R. Allen; Allen F. Anderson; Daniel E. Cooper; Thomas M. DeBerardino; Warren R. Dunn; Brett A. Lantz; Michael J. Stuart; Elizabeth A. Garofoli; John P. Albright; Annunziato Amendola; Jack T. Andrish; Christopher C. Annunziata; Robert A. Arciero; Bernard R. Bach; Champ L. Baker; Arthur R. Bartolozzi; Keith M. Baumgarten; Jeffery R. Bechler; Jeffrey H. Berg; Geoffrey A. Bernas; Stephen F. Brockmeier; Robert H. Brophy; J. Brad Butler; John D. Campbell; James L. Carey

Background: Most surgeons believe that graft choice for anterior cruciate ligament (ACL) reconstruction is an important factor related to outcome; however, graft choice for revision may be limited due to previously used grafts. Hypotheses: Autograft use would result in increased sports function, increased activity level, and decreased osteoarthritis symptoms (as measured by validated patient-reported outcome instruments). Autograft use would result in decreased graft failure and reoperation rate 2 years after revision ACL reconstruction. Study Design: Cohort study; Level of evidence, 2. Methods: Patients undergoing revision ACL reconstruction were identified and prospectively enrolled by 83 surgeons at 52 sites. Data collected included baseline demographics, surgical technique, pathologic abnormalities, and the results of a series of validated, patient-reported outcome instruments (International Knee Documentation Committee [IKDC], Knee injury and Osteoarthritis Outcome Score [KOOS], Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC], and Marx activity rating score). Patients were followed up at 2 years and asked to complete the identical set of outcome instruments. Incidences of additional surgery and reoperation due to graft failure were also recorded. Multivariate regression models were used to determine the predictors (risk factors) of IKDC, KOOS, WOMAC, Marx scores, graft rerupture, and reoperation rate at 2 years after revision surgery. Results: A total of 1205 patients (697 [58%] males) were enrolled. The median age was 26 years. In 88% of patients, this was their first revision, and 341 patients (28%) were undergoing revision by the surgeon who had performed the previous reconstruction. The median time since last ACL reconstruction was 3.4 years. Revision using an autograft was performed in 583 patients (48%), allograft was used in 590 (49%), and both types were used in 32 (3%). Questionnaire follow-up was obtained for 989 subjects (82%), while telephone follow-up was obtained for 1112 (92%). The IKDC, KOOS, and WOMAC scores (with the exception of the WOMAC stiffness subscale) all significantly improved at 2-year follow-up (P < .001). In contrast, the 2-year Marx activity score demonstrated a significant decrease from the initial score at enrollment (P < .001). Graft choice proved to be a significant predictor of 2-year IKDC scores (P = .017). Specifically, the use of an autograft for revision reconstruction predicted improved score on the IKDC (P = .045; odds ratio [OR] = 1.31; 95% CI, 1.01-1.70). The use of an autograft predicted an improved score on the KOOS sports and recreation subscale (P = .037; OR = 1.33; 95% CI, 1.02-1.73). Use of an autograft also predicted improved scores on the KOOS quality of life subscale (P = .031; OR = 1.33; 95% CI, 1.03-1.73). For the KOOS symptoms and KOOS activities of daily living subscales, graft choice did not predict outcome score. Graft choice was a significant predictor of 2-year Marx activity level scores (P = .012). Graft rerupture was reported in 37 of 1112 patients (3.3%) by their 2-year follow-up: 24 allografts, 12 autografts, and 1 allograft and autograft. Use of an autograft for revision resulted in patients being 2.78 times less likely to sustain a subsequent graft rupture compared with allograft (P = .047; 95% CI, 1.01-7.69). Conclusion: Improved sports function and patient-reported outcome measures are obtained when an autograft is used. Additionally, use of an autograft shows a decreased risk in graft rerupture at 2-year follow-up. No differences were noted in rerupture or patient-reported outcomes between soft tissue and bone–patellar tendon–bone grafts. Surgeon education regarding the findings of this study has the potential to improve the results of revision ACL reconstruction.


American Journal of Sports Medicine | 2010

Anatomical Confirmation of the Use of Radiographic Landmarks in Medial Patellofemoral Ligament Reconstruction

John Redfern; Ganesh V. Kamath; Robert T. Burks

Background A recent study has described radiographic landmarks for femoral insertion of the medial patellofemoral ligament. Clinical relevance and application of these landmarks for surgical reconstruction have yet to be determined. Hypothesis Radiographic landmarks can be used to accurately determine the femoral insertion of the medial patellofemoral ligament in a percutaneous fluoroscopically guided surgical technique. Study Design Descriptive laboratory study Methods The femoral insertion of the medial patellofemoral ligament was estimated using fluoroscopy in 8 fresh-frozen human cadaveric knees. The knees were dissected and the true anatomical medial patellofemoral ligament femoral insertion was identified. Radiographic markers were placed on both the estimated and anatomical medial patellofemoral ligament and a repeat lateral radiograph was performed. Using imaging software, the distance between the true anatomical insertion and the fluoroscopically determined insertion was calculated. Results All 8 points determined by fluoroscopically guided pin placement averaged less than 4 mm from the anatomical insertion. The radiographic landmark method consistently placed the origin on average 2.5 mm anterior and 0.6 mm distal to the anatomical insertion. Conclusion Radiographic landmarks determined by fluoroscopy can be used to accurately reproduce the femoral insertion of the medial patellofemoral ligament in ligament reconstruction. Clinical Relevance Confirming the use of radiographic landmarks to determine the medial patellofemoral ligament femoral insertion may help to increase accuracy and precision in ligament reconstruction and minimize surgical dissection.


American Journal of Sports Medicine | 2014

Anterior Cruciate Ligament Injury, Return to Play, and Reinjury in the Elite Collegiate Athlete Analysis of an NCAA Division I Cohort

Ganesh V. Kamath; Timothy Murphy; R. Alexander Creighton; Neal Viradia; Timothy N. Taft; Jeffrey T. Spang

Background: Graft survivorship, reinjury rates, and career length are poorly understood after anterior cruciate ligament (ACL) reconstruction in the elite collegiate athlete. The purpose of this study was to examine the outcomes of ACL reconstruction in a National Collegiate Athletic Association (NCAA) Division I athlete cohort. Study Design: Case series; Level of evidence, 4. Methods: A retrospective chart review was performed of all Division I athletes at a single public university from 2000 to 2009 until completion of eligibility. Athletes were separated into 2 cohorts: those who underwent precollegiate ACL reconstruction (PC group) and those who underwent intracollegiate reconstruction (IC group). Graft survivorship, reoperation rates, and career length information were collected. Results: Thirty-five athletes were identified with precollegiate reconstruction and 54 with intracollegiate reconstruction. The PC group had a 17.1% injury rate with the original graft, with a 20.0% rate of a contralateral ACL injury. For the IC group, the reinjury rates were 1.9% with an ACL graft, with an 11.1% rate of a contralateral ACL injury after intracollegiate ACL reconstruction. The athletes in the PC group used 78% of their total eligibility (average, 3.11 years). The athletes in the IC group used an average of 77% of their remaining NCAA eligibility; 88.3% of those in the IC group played an additional non-redshirt year after their injury. The reoperation rate for the PC group was 51.4% and was 20.4% for the IC group. Conclusion: Reoperation and reinjury rates are high after ACL reconstruction in the Division I athlete. Precollegiate ACL reconstruction is associated with a very high (37.1%) rate of repeat ACL reinjuries to the graft or opposite knee. The majority of athletes are able to return to play after successful reconstruction.


Journal of Bone and Joint Surgery, American Volume | 2014

Osteoarthritis classification scales: Interobserver reliability and arthroscopic correlation

Rick W. Wright; James R. Ross; Amanda K. Haas; Laura J. Huston; Elizabeth A. Garofoli; David Harris; Kushal Patel; David Pearson; Jake Schutzman; Majd Tarabichi; David Ying; John P. Albright; Christina R. Allen; Annunziato Amendola; Allen F. Anderson; Jack T. Andrish; Christopher C. Annunziata; Robert A. Arciero; Bernard R. Bach; Champ L. Baker; Arthur R. Bartolozzi; Keith M. Baumgarten; Jeffery R. Bechler; Jeffrey H. Berg; Geoffrey A. Bernas; Stephen F. Brockmeier; Robert H. Brophy; J. Brad Butler; John D. Campbell; James E. Carpenter

BACKGROUND Osteoarthritis of the knee is commonly diagnosed and monitored with radiography. However, the reliability of radiographic classification systems for osteoarthritis and the correlation of these classifications with the actual degree of confirmed degeneration of the articular cartilage of the tibiofemoral joint have not been adequately studied. METHODS As the Multicenter ACL (anterior cruciate ligament) Revision Study (MARS) Group, we conducted a multicenter, prospective longitudinal cohort study of patients undergoing revision surgery after anterior cruciate ligament reconstruction. We followed 632 patients who underwent radiographic evaluation of the knee (an anteroposterior weight-bearing radiograph, a posteroanterior weight-bearing radiograph made with the knee in 45° of flexion [Rosenberg radiograph], or both) and arthroscopic evaluation of the articular surfaces. Three blinded examiners independently graded radiographic findings according to six commonly used systems-the Kellgren-Lawrence, International Knee Documentation Committee, Fairbank, Brandt et al., Ahlbäck, and Jäger-Wirth classifications. Interobserver reliability was assessed with use of the intraclass correlation coefficient. The association between radiographic classification and arthroscopic findings of tibiofemoral chondral disease was assessed with use of the Spearman correlation coefficient. RESULTS Overall, 45° posteroanterior flexion weight-bearing radiographs had higher interobserver reliability (intraclass correlation coefficient = 0.63; 95% confidence interval, 0.61 to 0.65) compared with anteroposterior radiographs (intraclass correlation coefficient = 0.55; 95% confidence interval, 0.53 to 0.56). Similarly, the 45° posteroanterior flexion weight-bearing radiographs had higher correlation with arthroscopic findings of chondral disease (Spearman rho = 0.36; 95% confidence interval, 0.32 to 0.39) compared with anteroposterior radiographs (Spearman rho = 0.29; 95% confidence interval, 0.26 to 0.32). With respect to standards for the magnitude of the reliability coefficient and correlation coefficient (Spearman rho), the International Knee Documentation Committee classification demonstrated the best combination of good interobserver reliability and medium correlation with arthroscopic findings. CONCLUSIONS The overall estimates with the six radiographic classification systems demonstrated moderate (anteroposterior radiographs) to good (45° posteroanterior flexion weight-bearing radiographs) interobserver reliability and medium correlation with arthroscopic findings. The International Knee Documentation Committee classification assessed with use of 45° posteroanterior flexion weight-bearing radiographs had the most favorable combination of reliability and correlation. LEVEL OF EVIDENCE Diagnostic Level I. See Instructions for Authors for a complete description of levels of evidence.


American Journal of Sports Medicine | 2016

Meniscal and Articular Cartilage Predictors of Clinical Outcome After Revision Anterior Cruciate Ligament Reconstruction

Rick W. Wright; Laura J. Huston; Samuel K. Nwosu; Amanda K. Haas; Christina R. Allen; Allen F. Anderson; Daniel E. Cooper; Thomas M. DeBerardino; Warren R. Dunn; Brett A. Lantz; Barton J. Mann; Kurt P. Spindler; Michael J. Stuart; John P. Albright; Annunziato Amendola; Jack T. Andrish; Christopher C. Annunziata; Robert A. Arciero; Bernard R. Bach; Champ L. Baker; Arthur R. Bartolozzi; Keith M. Baumgarten; Jeffery R. Bechler; Jeffrey H. Berg; Geoffrey A. Bernas; Stephen F. Brockmeier; Robert H. Brophy; J. Brad Butler; John D. Campbell; James L. Carey

Background: Revision anterior cruciate ligament (ACL) reconstruction has been documented to have worse outcomes compared with primary ACL reconstructions. Purpose/Hypothesis: The purpose of this study was to determine if the prevalence, location, and/or degree of meniscal and chondral damage noted at the time of revision ACL reconstruction predicts activity level, sports function, and osteoarthritis symptoms at 2-year follow-up. The hypothesis was that meniscal loss and high-grade chondral damage noted at the time of revision ACL reconstruction will result in lower activity levels, decreased sports participation, more pain, more stiffness, and more functional limitation at 2 years after revision surgery. Study Design: Cohort study; Level of evidence, 2. Methods: Between 2006 and 2011, a total of 1205 patients who underwent revision ACL reconstruction by 83 surgeons at 52 hospitals were accumulated for study of the relationship of meniscal and articular cartilage damage to outcome. Baseline demographic and intraoperative data, including the International Knee Documentation Committee (IKDC) subjective knee evaluation, Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx activity score, were collected initially and at 2-year follow-up to test the hypothesis. Regression analysis was used to control for age, sex, body mass index, smoking status, activity level, baseline outcome scores, revision number, time since last ACL reconstruction, incidence of having a previous ACL reconstruction on the contralateral knee, previous and current meniscal and articular cartilage injury, graft choice, and surgeon years of experience to assess the meniscal and articular cartilage risk factors for clinical outcomes 2 years after revision ACL reconstruction. Results: At 2-year follow-up, 82% (989/1205) of the patients returned their questionnaires. It was found that previous meniscal injury and current articular cartilage damage were associated with the poorest outcomes, with prior lateral meniscectomy and current grade 3 to 4 trochlear articular cartilage changes having the worst outcome scores. Activity levels at 2 years were not affected by meniscal or articular cartilage pathologic changes. Conclusion: Prior lateral meniscectomy and current grade 3 to 4 changes of the trochlea were associated with worse outcomes in terms of decreased sports participation, more pain, more stiffness, and more functional limitation at 2 years after revision surgery, but they had no effect on activity levels. Registration: NCT00625885


Orthopaedic Journal of Sports Medicine | 2014

Surgical Trends in the Treatment of Superior Labrum Anterior and Posterior (SLAP) Lesions of the Shoulder. Analysis of Data from the American Board of Orthopaedic Surgery Certification Examination Database

Brendan Mackinnon-Patterson; Robert A. Creighton; Jeffrey T. Spang; Ganesh V. Kamath

Objectives: After failure of conservative treatment, surgical repair has long been the primary treatment option for unstable superior labrum anterior and posterior (SLAP) lesions of the shoulder. There is growing evidence supporting both biceps tenotomy and tenodesis as effective alternative treatments for SLAP lesions. The surgical trends among recent graduates, however, have not been evaluated. The goal of this study was to determine the rates of SLAP repair, biceps tenodesis, and biceps tenotomy for patients with isolated SLAP tears. As a secondary goal, we aimed to determine the rates of SLAP repair, biceps tenodesis, and biceps tenotomy for patients with SLAP tears undergoing concomitant rotator cuff repair. Methods: A query of the American board of orthopaedic surgery (ABOS) certification examination database was performed from 2002-2011. The database was searched for patients with isolated SLAP lesions undergoing SLAP repair, biceps tenodesis, or biceps tenotomy. The database was then queried a second time for patients with SLAP lesions undergoing concomitant arthroscopic rotator cuff repair, to determine the rates of SLAP repair, biceps tenodesis, or biceps tenotomy. Results: From 2002-2011 there were 8,963 cases reported for treatment of an isolated SLAP lesion, and 1540 cases reported for the treatment of SLAP lesion with concomitant rotator cuff repair. Over the study period, for patients with isolated SLAP lesions the proportion of SLAP repairs decreased from 69.3% to 44.8% (p<0.0001), while the proportion of biceps tenodesis increased from 0.2% to 9.3% (p<0.0001) and the proportion of biceps tenotomy increased from 0.4% to 1.7% (p=0.018). For patients undergoing concomitant rotator cuff repair, similar trends were observed as the proportion of SLAP repairs decreased from 60.2% to 15.3% (p<0.0001), while the proportion of those undergoing biceps tenodesis or tenotomy increased from 1.2% to 20.3% (p<0.0001). There was also a significant difference in the mean age of patients undergoing SLAP repair (37.1 years of age) vs biceps tenodesis (48.7 years of age) vs biceps tenotomy (55.7 years of age) (p <0.0001). Surgeons with a declared subspecialty in Shoulder and Elbow surgery performed biceps tenodesis for 17% of isolated SLAP tears, whereas candidates with a declared subspecialty in Hand and Upper Extremity, Sports Medicine, and General Orthopaedics utilized biceps tenodesis in 2-3% of cases involving isolated SLAP tears (p<0.05). Conclusion: Practice trends for orthopaedic board candidates indicate the proportion of SLAP repairs has decreased over time with an expected increase in biceps tenodesis and tenotomy. Increased patient age correlates with likelihood of treatment with biceps tenodesis or tenotomy versus SLAP repair. Candidate surgeons with subspecialty training in Shoulder and Elbow surgery perform more biceps tenodesis for isolated SLAP tears as compared to other subspecialty trained surgeons.


Journal of Bone and Joint Surgery, American Volume | 2008

Patient Compliance with Clinical Follow-up After Total Joint Arthroplasty

John C. Clohisy; Ganesh V. Kamath; Gregory D. Byrd; Karen Steger-May; Rick W. Wright

BACKGROUND Periodic clinical and radiographic evaluation is commonly recommended by orthopaedic surgeons to monitor patients following total joint arthroplasty, yet the compliance with and efficacy of patient follow-up protocols have not been well defined. The purpose of this study was to evaluate patient compliance with early clinical follow-up after total hip arthroplasty or total knee arthroplasty. METHODS We performed a retrospective review of clinical follow-up compliance for 776 patients who had undergone a total joint arthroplasty in the lower extremity. This cohort included 505 total hip arthroplasties (372 primary and 133 revision procedures) and 271 total knee arthroplasties (195 primary and seventy-six revision procedures). The patients were given one-time verbal instructions by the treating surgeon at the three-month postoperative visit to return for the one-year follow-up evaluation. At the one-year follow-up evaluation, those who returned were once again verbally instructed to return a year later. Demographic factors, functional hip and knee scores, and follow-up compliance at one and two years after surgery were assessed. RESULTS Patient compliance with clinical follow-up after all arthroplasties was 61% at one year and 36% at two years. With use of a multivariate model for patients who had total hip arthroplasty, the analyses showed that a revision hip procedure (p = 0.006), younger patient age (p = 0.04), and a higher preoperative Harris hip score for gait (p = 0.04) were associated with follow-up compliance at two years. Of the factors analyzed for patients who had total knee arthroplasty, only nonwhite race (p = 0.03) was found to be a positive predictor of follow-up compliance at the two-year follow-up interval. CONCLUSIONS Patient compliance with clinical follow-up after total joint arthroplasty in response to a verbal request made by the surgeon once at three months and once at one year postoperatively was poor in this series. These data indicate that this method (one-time verbal instruction) is insufficient to ensure compliance for follow-up after total joint arthroplasty.


American Journal of Sports Medicine | 2013

Biomechanical Analysis of a Double-Loaded Glenoid Anchor Configuration Can Fewer Anchors Provide Equivalent Fixation?

Ganesh V. Kamath; Stephen A. Hoover; R. Alexander Creighton; Paul S. Weinhold; Aaron E. Barrow; Jeffrey T. Spang

Background: Bankart repair with multiple anchor holes concentrated in the anterior-inferior glenoid may contribute to glenoid weakening and potentially may induce glenoid failure. Purpose: To compare the biomechanical strength of a Bankart repair construct that used 3 single-loaded suture anchors versus a repair construct that used 2 double-loaded suture anchors. Study Design: Comparative laboratory study. Methods: A standard Bankart lesion was created in 18 human cadaveric shoulders (9 matched pairs). Within each matched pair, 1 repair construct used 3 single-loaded anchors, whereas the other used 2 double-loaded suture anchors. Measured outcomes (load, stiffness, and energy absorbed) were recorded at failure and at 2 mm of labral displacement. Constructs were loaded to failure with a materials testing device that had differential variable reluctance transducers for displacement measurements. Results: The double-loaded anchor construct had a significantly higher ultimate tensile load (944 ± 231 vs 784 ± 287 N; P = .03). For the other measures (load at 2 mm of displacement, energy absorbed at failure and at 2 mm of displacement and stiffness), there were no significant differences between tested constructs. Conclusion: A Bankart repair construct that used 2 double-loaded anchors was either superior to or equal to a repair construct that used 3 single-loaded anchors in all measured outcomes. Clinical Relevance: Using 2 double-loaded suture anchors for a Bankart repair may limit anchor holes in the glenoid and reduce the risk of postsurgical glenoid fracture while providing a stable repair construct.

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Jeffrey T. Spang

University of North Carolina at Chapel Hill

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Rick W. Wright

The Ohio State University Wexner Medical Center

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Allen F. Anderson

Washington University in St. Louis

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Bernard R. Bach

Rush University Medical Center

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Champ L. Baker

Georgia Regents University

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Christopher C. Annunziata

Washington University in St. Louis

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