Gayle Wallace DeBoom

Metastatic tumors of the mandibular condyle: Review of the literature and report of a case

A metastatic tumor involving the mandibular condyle presented symptoms of temporomandibular joint (TMJ) dysfunction. Positive identification of the primary malignant lesion as prostatic adenocarcinoma was accomplished through the use of immunohistochemical stains for prostate-specific antigen and subsequent prostate biopsy. A review of the literature revealed fifteen additional cases of metastatic lesions of the mandibular condyle, seven of which also demonstrated TMJ-related symptoms as the initial manifestation of malignant disease. Such cases represent a diagnostic challenge, both clinically and microscopically. Symptoms of TMJ dysfunction coupled with radiographic evidence of a destructive lesion or pathologic fracture should suggest a possible malignant process indicating the need for biopsy. Subsequent examination of routine sections in combination with the use of selected stains, including immunohistochemistry may be helpful in identification of the primary tumor site.

Cylindrical cell papilloma.

A case of cylindrical cell papilloma (CCP) arising in the maxillary sinus is described. Light and electron microscopic findings revealed the characteristic oncocytic nature of the neoplasm. A review of the literature confirms the rarity of CCP and its behavioral similarities to the more common inverted papilloma. The relatively high rate of recurrence, coupled with the increased risk of associated malignancy, necessitates the recognition and appropriate treatment of CCP.