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Dive into the research topics where Geetika Khanna is active.

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Featured researches published by Geetika Khanna.


Skeletal Radiology | 2007

Imaging of cervical spine injuries of childhood

Geetika Khanna; Georges Y. El-Khoury

Cervical spine injuries of children, though rare, have a high morbidity and mortality. The pediatric cervical spine is anatomically and biomechanically different from that of adults. Hence, the type, level and outcome of cervical spine injuries in children are different from those seen in adults. Normal developmental variants seen in children can make evaluation of the pediatric cervical spine challenging. This article reviews the epidemiology of pediatric cervical spine trauma, normal variants seen in children and specific injuries that are more common in the pediatric population. We also propose an evidence-based imaging protocol to avoid unnecessary imaging studies and minimize radiation exposure in children.


Pediatric Radiology | 2008

Gastroenteropancreatic neuroendocrine tumors in children and young adults

Geetika Khanna; Sue M. O’Dorisio; Yusuf Menda; Patricia A. Kirby; Simon C. S. Kao; Yutaka Sato

We review the imaging findings of pediatric gastroenteropancreatic neuroendocrine tumors (GEP-NETs) using contemporary anatomic and molecular imaging techniques. A low index of suspicion can result in significant delays in diagnosis of pediatric GEP-NETs. A multimodality imaging approach, using both anatomic and functional imaging, is essential in the diagnosis, staging, and surveillance of these potentially malignant tumors.


Pediatric Blood & Cancer | 2008

Somatostatin receptor scintigraphy in surveillance of pediatric brain malignancies

Geetika Khanna; M. Sue O'Dorisio; Yusuf Menda; Charles M. Glasier; Barry R. DeYoung; Brian J. Smith; Michael M. Graham; Malik E. Juweid

Somatostatin receptor scintigraphy (SRS) has been successfully used in imaging PBTs and, as a functional imaging modality, may be better able to differentiate tumor from scar/necrosis. This retrospective study evaluates the role of SRS in post‐treatment surveillance of PBTs.


Pediatric Radiology | 2008

Partial tear of the quadriceps tendon in a child

Geetika Khanna; George Y. El-Khoury

We present a case of partial rupture of the quadriceps tendon in an 8-year-old girl. This is one of the youngest patients reported with a quadriceps tendon rupture, an entity seen predominantly in middle-aged people. The strength of the muscle tendon unit in a child makes tendon injuries extremely unusual as compared to apophyseal avulsions. The MR imaging findings of this unusual pediatric injury are illustrated.


Journal of Clinical Oncology | 2018

Impact of Surveillance Imaging Modality on Survival After Recurrence in Patients With Favorable-Histology Wilms Tumor: A Report From the Children’s Oncology Group

Elizabeth Mullen; Yueh-Yun Chi; Emily Hibbitts; James R. Anderson; Katarina J. Steacy; James I. Geller; Daniel M. Green; Geetika Khanna; Marcio H. Malogolowkin; Paul E. Grundy; Conrad V. Fernandez; Jeffrey S. Dome

PURPOSEnThe use of computed tomography (CT) for routine surveillance to detect recurrence in patients with Wilms tumor (WT) has increased in recent years. The utility of CT, despite increased risk and cost, to improve outcome for these patients is unknown. We conducted a retrospective analysis with patients enrolled in the fifth National Wilms Tumor Study (NWTS-5) to determine if surveillance with CT correlates with improved overall survival (OS) after recurrence compared with chest x-ray (CXR) and abdominal ultrasound (US).nnnPATIENTS AND METHODSnOverall, 281 patients with recurrent unilateral favorable-histology WT were reviewed to assess how WT recurrence was detected: sign/symptoms (SS), surveillance imaging (SI) with CT scan, or SI with CXR/US.nnnRESULTSnThe estimated 5-year OS rate after relapse was 67% (95% CI, 61% to 72%). Twenty-five percent of recurrences were detected with SS; 48.5%, with CXR/US; and 26.5%, with CT. Patients with SS had a 5-year OS rate of 59% (95% CI, 46% to 72%) compared with 70% (95% CI, 63% to 77%; P = .23) for those detected by SI. Recurrences detected by CT had a shorter median time from diagnosis to recurrence (0.60 years) compared with SS (0.91 years) or CXR/US (0.86 years; P = .003). For recurrences detected by SI, more tumor foci at relapse ( P < .001) and size of the largest focus greater than 2 cm ( P = .02) were associated with inferior OS. However, there was no difference in OS after relapse when recurrence was detected by CT versus CXR/US (5-year OS rate, 65% v 73%; P = .20).nnnCONCLUSIONnIn patients with favorable-histology WT, elimination of CT scans from surveillance programs is unlikely to compromise survival but would result in substantial reduction in radiation exposure and health care costs.


Pediatric Blood & Cancer | 2014

Time to disease progression in children with relapsed or refractory neuroblastoma treated with ABT-751: A report from the Children's Oncology Group (ANBL0621): Phase 2 Trial: ABT-751 in Neuroblastoma

Elizabeth Fox; Yael P. Mosse; Holly M. Meany; James G. Gurney; Geetika Khanna; Hollie A. Jackson; Gary Gordon; Suzanne Shusterman; Julie R. Park; Susan L. Cohn; Peter C. Adamson; Wendy B. London; John M. Maris; Frank M. Balis

ABT‐751, an orally bioavailable sulfonamide binds the colchicine site of beta‐tubulin and inhibits microtubule polymerizaton. Prior phase I studies established the recommended dose in children with solid tumors as 200u2009mg/m2 PO dailyu2009×u20097 days every 21 days and subjects with neuroblastoma experienced prolonged stable disease. We conducted a phase 2 study (NCT00436852) in children and adolescents with progressive neuroblastoma to determine if ABT‐751 prolonged the time to progression (TTP) compared to a hypothesized standard based on a historical control population.


Pediatric Blood & Cancer | 2012

Evaluation of diagnostic performance of CT for detection of tumor thrombus in children with Wilms tumor: A report from the Children's Oncology Group: Wilms Tumor Thrombus Detection

Geetika Khanna; Nancy S. Rosen; James R. Anderson; Peter F. Ehrlich; Jeffrey S. Dome; Kenneth W. Gow; Elizabeth J. Perlman; Douglas C. Barnhart; Kathryn Karolczuk; Paul E. Grundy

Pre‐operative assessment of intravascular extension of Wilms tumor is essential to guide management. Our aim is to evaluate the diagnostic performance of multidetector CT in detection of tumor thrombus in Wilms tumor.


Journal of Clinical Oncology | 2014

Treatment of stage IV favorable histology Wilms tumor with incomplete lung metastasis response after chemotherapy: A report from Children's Oncology Group study AREN0533.

David Dix; Eric J. Gratias; Nita L. Seibel; James R. Anderson; Elizabeth Mullen; James I. Geller; Geetika Khanna; John A. Kalapurakal; Elizabeth J. Perlman; Peter F. Ehrlich; Marcio H. Malogolowkin; Paul E. Grundy; Jeffrey S. Dome


Journal of Clinical Oncology | 2015

Omission of lung radiation in patients with stage IV favorable histology Wilms Tumor (FHWT) showing complete lung nodule response after chemotherapy: A report from Children’s Oncology Group study AREN0533.

David Dix; Eric J. Gratias; Nita L. Seibel; James R. Anderson; Elizabeth Mullen; James I. Geller; Geetika Khanna; John A. Kalapurakal; Elizabeth J. Perlman; Peter F. Ehrlich; Marcio H. Malogolowkin; Paul E. Grundy; Jeffrey S. Dome


Operative Techniques in Neurosurgery | 2005

Imaging of the Craniovertebral Junction

Geetika Khanna; Yutaka Sato

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Jeffrey S. Dome

Children's National Medical Center

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James I. Geller

Cincinnati Children's Hospital Medical Center

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Marcio H. Malogolowkin

Children's Hospital of Wisconsin

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Eric J. Gratias

University of Tennessee at Chattanooga

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