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Dive into the research topics where Gene Kurosawa is active.

Publication


Featured researches published by Gene Kurosawa.


Development Genes and Evolution | 2007

Duplicated Abd-B class genes in medaka hoxAa and hoxAb clusters exhibit differential expression patterns in pectoral fin buds

Naofumi Takamatsu; Gene Kurosawa; Masayoshi Takahashi; Ryouichi Inokuma; Minoru Tanaka; Akira Kanamori; Hiroshi Hori

Hox genes form clusters. Invertebrates and Amphioxus have only one hox cluster, but in vertebrates, they are multiple, i.e., four in the basal teleost fish Polyodon and tetrapods (HoxA, B, C, D), but seven or eight in common teleosts. We earlier completely sequenced the entire hox gene loci in medaka fish, showing a total of 46 hox genes to be encoded in seven clusters (hoxAa, Ab, Ba, Bb, Ca, Da, Db). Among them, hoxAa, hoxAb and hoxDa clusters are presumed to be important for fin-to-limb evolution because of their key role in forelimb and pectoral fin development. In the present study, we compared genome organization and nucleotide sequences of the hoxAa and hoxAb clusters to these of tetrapod HoxA clusters, and found greater similarity in hoxAa case. We then analyzed expression of Abd-B family genes in the clusters. In the trunk, those from the hoxAa cluster, i.e., hoxA9a, hoxA10a, hoxA11a and hoxA13a, were expressed in a manner keeping the colinearity rule of the hox expression as those of tetrapods, while those from the hoxAb cluster, i.e., hoxA9b, hoxA10b, hoxA11b and hoxA13b, were not. In the pectoral fins, the hoxAa cluster was expressed in split domains and did not obey the rule. By contrast, those from the hoxAb and hoxDa clusters were expressed in a manner keeping the rule, i.e., an ancestral pattern similar to those of tetrapods. It is plausible that this differential expression of the two clusters is caused by changes occurred in global control regions after cluster duplications.


Gene | 2006

Organization and structure of hox gene loci in medaka genome and comparison with those of pufferfish and zebrafish genomes.

Gene Kurosawa; Naofumi Takamatsu; Masayoshi Takahashi; Mariko Sumitomo; Emi Sanaka; Kouji Yamada; Kazuhiro Nishii; Masaru Matsuda; Shuichi Asakawa; Hiroshi Ishiguro; Keiji Miura; Yoshikazu Kurosawa; Nobuyoshi Shimizu; Yuji Kohara; Hiroshi Hori


Archive | 2007

METHOD OF CLASSIFYING ANTIBODY, METHOD OF IDENTIFYING ANTIGEN, METHOD OF OBTAINING ANTIBODY OR ANTIBODY SET, METHOD OF CONSTRUCTING ANTIBODY PANEL AND ANTIBODY OR ANTIBODY SET AND USE OF THE SAME

Atsushi Sugioka; Mototaka Sugiura; Yasushi Akahori; Nobuhiro Hayashi; Akihiko Takasaki; Miwa Morita; Gene Kurosawa; Mariko Sumitomo; Susumu Tsutsumi; Keiko Ogawa; Kazuki Matsuda; Chiho Muramatsu; Noriko Satou; Masachika Azuma; Yoshinori Ukai; Kazuhiro Suzuki; Yoshikazu Kurosawa; Miho Tanaka; Mamoru Shiraishi


Archive | 2006

Anti-IgSF4 Antibody and Utilization of the Same

Yoshikazu Kurosawa; Yasushi Akahori; Nobuhiro Takahashi; Atsushi Sugioka; Nobuhiro Hayashi; Akihiko Takasaki; Kazuhiro Suzuki; Miwa Morita; Gene Kurosawa; Sari Fujiyama; Susumu Tsustumi; Keiko Ogawa; Kazuki Matsuda; Chiho Muramatsu; Yoshitaka Iba; Mariko Sumitomo; Masachika Azuma; Yoshinori Ukai; Kazuhiro Morishita


Biochemical and Biophysical Research Communications | 1999

Hox Gene Complexity in Medaka Fish May Be Similar to That in Pufferfish Rather Than Zebrafish

Gene Kurosawa; Kouji Yamada; Hiroshi Ishiguro; Hiroshi Hori


Archive | 2014

Anticorps qui réagit spécifiquement avec l'intégrine humaine a6b4

Kazuhiro Morishita; 和広 森下; Kazuko Kaneda; 加珠子 兼田; Yoshikazu Kurosawa; 良和 黒澤; Gene Kurosawa; 仁 黒澤; Katsuyuki Mitomo; 克之 見供; Katsushi Kouda; 克志 甲田; Yoshinori Ukai; 由範 鵜飼


Archive | 2009

Composition destinee a neutraliser la toxine botulinique de type a et anticorps humain anti-toxine botulinique de type a

Masachika Azuma; Motohide Takahashi; Shunji Kozaki; Masafumi Mukamoto; Tomoko Kohda; Gene Kurosawa; Yoshikazu Kurosawa


Archive | 2007

Nouvel anticorps anti-cd73

Atsushi Sugioka; Mototaka Sugiura; Yasushi Akahori; Nobuhiro Hayashi; Akihiko Takasaki; Miwa Morita; Gene Kurosawa; Mariko Sumitomo; Susumu Tsutsumi; Keiko Ogawa; Kazuki Matsuda; Chiho Muramatsu; Noriko Satou; Masachika Azuma; Yoshinori Ukai; Kazuhiro Suzuki; Yoshikazu Kurosawa; Miho Tanaka; Mamoru Shiraishi


Archive | 2007

Procédé de classification d'antigène, procédé d'identification d'antigène, procédé d'obtention d' un ensemble d'antigènes ou d'anticorps, procédés de construction d'un panel d'anticorps, anticorps et ens

Atsushi Sugioka; Mototaka Sugiura; Yasushi Akahori; Nobuhiro Hayashi; Akihiko Takasaki; Miwa Morita; Gene Kurosawa; Mariko Sumitomo; Susumu Tsutsumi; Keiko Ogawa; Kazuki Matsuda; Chiho Muramatsu; Noriko Satou; Masachika Azuma; Yoshinori Ukai; Kazuhiro Suzuki; Yoshikazu Kurosawa; Miho Tanaka; Mamoru Shiraishi


Archive | 2007

Procédé pour l'identification des anticorps diagnostic ou thérapeutiques par cytométrie en flux

Atsushi Sugioka; Mototaka Sugiura; Yasushi Akahori; Nobuhiro Hayashi; Akihiko Takasaki; Miwa Morita; Gene Kurosawa; Mariko Sumitomo; Susumu Tsutsumi; Keiko Ogawa; Kazuki Matsuda; Chiho Muramatsu; Noriko Satou; Masachika Azuma; Yoshinori Ukai; Kazuhiro Suzuki; Yoshikazu Kurosawa; Miho Tanaka; Mamoru Shiraishi

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Yoshinori Ukai

Fujita Health University

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Kazuki Matsuda

Fujita Health University

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Keiko Ogawa

Fujita Health University

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