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Featured researches published by Genymphas B. Higgs.


Journal of Arthroplasty | 2013

Is Increased Modularity Associated With Increased Fretting and Corrosion Damage in Metal-On-Metal Total Hip Arthroplasty Devices?: A Retrieval Study

Genymphas B. Higgs; Josa Hanzlik; Daniel W. MacDonald; Jeremy L. Gilbert; Clare M. Rimnac; Steven M. Kurtz

This retrieval study documents taper damage at modular interfaces in retrieved MOM THA systems and investigates if increased modularity is associated with increased fretting and corrosion. One hundred thirty-four (134) heads and 60 stems (41 modular necks) of 8 different bearing designs (5 manufacturers) were analyzed. Damage at the shell-liner interface of 18 modular CoCr acetabular liners and the corresponding 11 acetabular shells was also evaluated. The results of this study support the hypothesis that fretting and corrosion damage occurs at a variety of modular component interfaces in contemporary MOM THAs. We also found that modularity of the femoral stem was associated with increased damage at the head. An analysis of component and patient variables revealed that dissimilar alloy pairing, larger head sizes, increased medio-lateral offsets and longer neck moment arms were all associated with increased taper damage at the modular interfaces.


European Spine Journal | 2013

Retrieval analysis of PEEK rods for posterior fusion and motion preservation

Steven M. Kurtz; Todd H. Lanman; Genymphas B. Higgs; Daniel W. MacDonald; Sigurd Berven; Jorge Isaza; Eual Phillips; Marla J. Steinbeck

IntroductionThe purpose of this study was to analyze explanted PEEK rod spinal systems in the context of their clinical indications. We evaluated damage to the implant and histological changes in explanted periprosthetic tissues.Methods12 patients implanted with 23 PEEK rods were revised between 2008 and 2012. PEEK rods were of the same design (CD Horizon Legacy, Medtronic, Memphis TN, USA). Retrieved components were assessed for surface damage mechanisms, including plastic deformation, scratching, burnishing, and fracture. Patient history and indications for PEEK rod implantation were obtained from analysis of the medical records.Results11/12 PEEK rod systems were employed for fusion at one level, and motion preservation at the adjacent level. Surgical complications in the PEEK cohort included a small dural tear in one case that was immediately repaired. There were no cases of PEEK rod fracture or pedicle screw fracture. Retrieved PEEK rods exhibited scratching, as well as impressions from the set screws and pedicle screw saddles. PEEK debris was observed in two patient tissues, which were located adjacent to PEEK rods with evidence of scratching and burnishing.ConclusionThis study documents the surface changes and tissue reactions for retrieved PEEK rod stabilization systems. Permanent indentations by the set screws and pedicle screws were the most prevalent observations on the surface of explanted PEEK rods.


Orthopedics | 2016

Total Knee Post-Cam Design Variations and Their Effects on Kinematics and Wear Patterns

William M. Mihalko; Julie Lowell; Genymphas B. Higgs; Steven M. Kurtz

Post-cam designs for posterior-stabilized total knee arthroplasy (TKA) implants have evolved over the last 2 decades. These designs have evolved from symmetric post and cam to asymmetric designs that include anterior post interactions to affect a kinematic change in full extension. All design changes have consequences on the resulting femorotibial contact kinematics and, depending on the amount of constraint built into the design, these changes may have significant consequences on the wear patterns on the tibial polyethylene insert. The current authors review the kinematic effects of symmetric and asymmetric cam designs and use a retrieval database of TKA implants obtained at the time of necropsy to show how different design variables may affect polyethylene wear patterns after 10 or more years of implantation or from modeled wear in simulators. More modern designs seem to have moved the post posteriorly and sloped the anterior aspect to avoid impingement of the anterior post in terminal flexion on the inferior aspect of the patella button. [Orthopedics. 2016; 39(3):S45-S49.].


Corrosion | 2017

Technical Note: Is Corrosion a Threat to the Strength of the Taper Connection in Femoral Components of Total Hip Replacements?

Genymphas B. Higgs; Daniel W. MacDonald; Julie Lowell; Alexander Padayatil; William M. Mihalko; Ryan Siskey; Jeremy L. Gilbert; Clare M. Rimnac; Steven M. Kurtz

Taper corrosion has been suggested as a possible contributor to in vivo disassociation of modular connections in total hip arthroplasty (THA) systems, but this relationship has not been explored ex...


Journal of Arthroplasty | 2017

Oxidation, Damage Mechanisms, and Reasons for Revision of Sequentially Annealed Highly Crosslinked Polyethylene in Total Knee Arthroplasty

Daniel W. MacDonald; Genymphas B. Higgs; Antonia F. Chen; Arthur L. Malkani; Michael A. Mont; Steven M. Kurtz

BACKGROUND Sequentially annealed, highly crosslinked polyethylene (HXLPE) has been used clinically in total knee arthroplasty (TKA) for over a decade. However, little is known about the revision reasons; its surface damage mechanisms; or its in vivo oxidative stability relative to conventional polyethylene. We asked whether retrieved HLXPE tibial inserts exhibited: (1) similar revision reasons; (2) improved resistance to surface damage; and (3) improved oxidative stability, when compared with conventional gamma inert sterilized polyethylene inserts. METHODS A total of 456 revised tibial inserts were collected in a multicenter retrieval program between 2000 and 2016. The implantation time for the HXLPE components was 1.8 ± 1.8 years, and for the control inserts it was 3.4 ± 2.7 years. Revision reasons were assessed based on medical records, radiographs, and examinations of the retrieved components. Surface damage was assessed using a semi-quantitative scoring method. Oxidation was measured using Fourier transform infrared spectroscopy. RESULTS The tibial inserts in both cohorts were revised most frequently for loosening, infection, and instability. The most commonly observed surface damage modes were burnishing, pitting, and scratching. Oxidation of the HXLPE inserts was, on average, low and similar to the control inserts at the bearing surface and the stabilizing post. CONCLUSIONS We observed evidence of in vivo oxidation in both HXLPE and control tibial inserts. We found no association between the levels of oxidation and the clinical performance of the HXLPE tibial components. The findings of this study document the revision reasons, surface damage modes, and oxidative behavior of sequentially annealed HXLPE for TKA.


Journal of Arthroplasty | 2016

Does Taper Size Have an Effect on Taper Damage in Retrieved Metal-on-Polyethylene Total Hip Devices?

Genymphas B. Higgs; Daniel W. MacDonald; Jeremy L. Gilbert; Clare M. Rimnac; Steven M. Kurtz; Antonia F. Chen; Gregg R. Klein; Brian R. Hamlin; Gwo-Chin Lee; Michael A. Mont; Harold E. Cates; Arthur L. Malkani; Matthew J. Kraay


International Orthopaedics | 2013

Oxidative properties and surface damage mechanisms of remelted highly crosslinked polyethylenes in total knee arthroplasty

Daniel W. MacDonald; Genymphas B. Higgs; Javad Parvizi; Gregg R. Klein; Mark A. Hartzband; Harlan B. Levine; Matthew J. Kraay; Clare M. Rimnac; Steven M. Kurtz


ASTM Symposium on Metal-on-Metal Total Hip Replacement Devices | 2013

Method of characterizing fretting and corrosion at the various taper connections of retrieved modular components from metal-on-metal total hip arthroplasty

Genymphas B. Higgs; Josa Hanzlik; Daniel W. MacDonald; William M. Kane; Judd S. Day; Gregg R. Klein; Javad Parvizi; Michael A. Mont; Matthew J. Kraay; John M. Martell; Jeremy L. Gilbert; Clare M. Rimnac; Steven M. Kurtz


Journal of Arthroplasty | 2017

Trunnion Failure of the Recalled Low Friction Ion Treatment Cobalt Chromium Alloy Femoral Head

Kenneth L. Urish; Brian R. Hamlin; Anton Y. Plakseychuk; Timothy J. Levison; Genymphas B. Higgs; Steven M. Kurtz; Anthony M. DiGioia


Symposium on Modularity and Tapers in Total Joint Replacement Devices | 2015

Microgrooved Surface Topography Does Not Influence Fretting Corrosion of Tapers in Total Hip Arthroplasty: Classification and Retrieval Analysis

Christina M. Arnholt; Richard Underwood; Daniel W. MacDonald; Genymphas B. Higgs; Antonia F. Chen; Gregg R. Klein; Brian R. Hamlin; Gwo Chin Lee; Michael Mont; Harold E. Cates; Arthur L. Malkani; Matthew J. Kraay; Clare M. Rimnac; Steven M. Kurtz

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Clare M. Rimnac

Case Western Reserve University

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Antonia F. Chen

Thomas Jefferson University

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