George D. Lundberg

A Comparison of Computer-Monitored Group Tests with Paper-and-Pencil Tests.

A test was administered to pharmacy students in two ways: using a computer-monitored, group-response system and using the conventional, paper-and-pencil method. Student performance on the two administrative modes was compared. Test-taking behavior for the two modes, as measured by the number and pattern of changed answers, was also compared. Three item formats (true-false, multiple-choice and matching) were analyzed separately.

Sickle cell trait: possible contributory cause of renal allograft failure

A black male with known sickle cell trait (hemoglobin AS) received two cadaveric renal transplants in succession. After excellent initial graft function he had what appeared clinically to be an acute rejection episode which could not be reversed by immunosuppressive therapy on either occasion. The histopathology of the removed allografts did not reveal a picture of acute rejection, but instead revealed extensive intravascular sickling of the erythrocytes. This is important especially for the transplant centers in the United States which may have a significant number of the black population among the renal allograft recipients.

Delta-9-tetrahydrocannabinol Levels in Street Samples of Marijuana and Hashish: Correlation to User Reactions

In a 6-year period, 435 alleged cannabis samples were accessioned by an urban street drug analysis program, and clinical histories were correlated with laboratory results. The most common reason for submission of a sample was suspicion of adulteration; however, such samples were usually unadulterated but had high potency as measured by delta 9-tetrahydrocannabinol concentration. Adverse reactions occurring in nonadulterated samples were not associated with high potencies. The validity of cannabis products distributed illicitly and analyzed was over 94%. Exotic varieties were more potent than less expensive cannabis. The absolute amount of delta 9-tetrahydrocannabinol ranged from 1.5 to 144.9 mg.