George M. Rubottom

Deuteration of pyridine derivatives : a very mild procedure

Abstract Ruthenium on carbon selectively catalyzes the hydrogen-deuterium exchange of pyridine derivatives at the ortho position. The reaction takes place at ambient temperature under mild conditions.

The reaction of aldehyde enol silyl ethers with lead(IV) acetate

Abstract The treatment of aldehyde enol silyl ethers 1 with lead(IV) acetate (LTA) using methylene chloride as solvent gives rise to the production of ⇌-acetoxy aldehydes 2 and glycolic ester derivatives 3 or enals 5 . Structural variations in 1 are used to explain the divergent trends. When 1 is treated with LTA/KOAc/AcOH, high yields of the corresponding ⇌-acetoxy aldehydes 2 are obtained with the formation of 3 and 5 being subverted.