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Dive into the research topics where George R. Allen is active.

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Featured researches published by George R. Allen.


Tetrahedron | 1964

The formation of steroid enolate anions by reductive procedures: The synthesis of 17-alkylprogesterones

Martin J. Weiss; Robert E. Schaub; George R. Allen; John F. Poletto; V. Pidacks; R.B. Conrow; C.J. Coscia

Abstract Treatment of a 16-dehydro, 17-acetoxy, 17-hydroxy or 17-bromopregn-20-one with a liquid ammonia solution of lithium, barium or calcium (and in at least one instance sodium) afforded an intermediate 17-enolate anion, which on reaction with the appropriate alkyl, allyl and benzyl halide furnished the corresponding 17-alkyl, allyl and benzyl-pregn-20-one. A very useful liquid-liquid partition column chromatographic procedure is described.


Journal of Organic Chemistry | 1970

Efficient synthesis of selected indenones

M. Brawner. Floyd; George R. Allen


Journal of Medicinal Chemistry | 1974

6-(Substituted phenyl)-5-substituted-4,5-dihydro-3(2H)-pyridazinones. Antihypertensive agents.

Francis J. McEvoy; George R. Allen


Journal of the American Chemical Society | 1964

The Mitomycin Antibiotics. Synthetic Studies. II.1 The Synthesis of 7-Methoxymitosene, an Antibacterial Agent

George R. Allen; John F. Poletto; Martin J. Weiss


Journal of the American Chemical Society | 1971

Addition reactions of the uniparticulate electrophile chlorosulfonyl isocyanate to highly strained bicyclic hydrocarbons

Leo A. Paquette; George R. Allen; Michael J. Broadhurst


Journal of the American Chemical Society | 1970

Unsaturated heterocyclic systems. LXX. Stereochemistry of the thermal fragmentation of .beta.-lactams. Comparison with the pyrolysis of 1-azetines

Leo A. Paquette; M. J. Wyvratt; George R. Allen


Journal of Organic Chemistry | 1968

Behavior of 2-carbomethoxy- and 2-acetyl-1,4-benzoquinone in the Nenitzescu indole syntheses

George R. Allen; Martin J. Weiss


Journal of Medicinal Chemistry | 1968

The Mitomycin Antibiotics. Synthetic Studies. XXII. Antibacterial Structure-Activity Relationships in the Indoloquinone Series

Martin J. Weiss; Gunnar Redin; George R. Allen; Albert Dornbush; Harry Lindsay; John F. Poletto; William A. Remers; Reta H. Roth; Adolf Slobada


Journal of the American Chemical Society | 1972

Ag+-catalyzed rearrangements. XII. Effect of methyl substitution on the competitive rearrangements of tricyclo[4.1.0.02,7]heptanes by silver(I) ion. Product and kinetic considerations

Leo A. Paquette; Stanley E. Wilson; Richard P. Henzel; George R. Allen


Journal of the American Chemical Society | 1970

Mechanism of the Nenitzescu indole synthesis and its utilization for the preparation of carbazoles

Ruddy Littell; George O. Morton; George R. Allen

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