Geraldine Ruth Mcfarlane
Princeton University
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Publication
Featured researches published by Geraldine Ruth Mcfarlane.
Bioorganic & Medicinal Chemistry Letters | 2009
David P. Rotella; Geraldine Ruth Mcfarlane; Alexander Alexei Greenfield; Cristina Grosanu; Albert J. Robichaud; Rajiah Aldrin Denny; Rolf W. Feenstra; Sara Núñez-García; Jan-Hendrik Reinders; Martina A.W. van der Neut; Andrew C. McCreary; Chris G. Kruse; Kelly Sullivan; Farhana Pruthi; Margaret Lai; Jean Zhang; Dianne Kowal; Tikva Carrick; Steven M. Grauer; Rachel Navarra; Radka Graf; Karen L. Marquis; Mark H. Pausch
A 5-fluoro-tetrahydrocarbazole serotonin reuptake inhibitor (SRI) building block was combined with a variety of linkers and dopamine D2 receptor ligands in an attempt to identify potent D2 partial agonist/SRI molecules for treatment of schizophrenia. This approach has the potential to treat a broader range of symptoms compared to existing therapies. Selected compounds in this series demonstrate high affinity for both targets and D2 partial agonism in cell-based and in vivo assays.
Journal of Medicinal Chemistry | 2004
Hassan M. Elokdah; Magid Abou-Gharbia; James K. Hennan; Geraldine Ruth Mcfarlane; Cheryl P. Mugford; Girija Krishnamurthy; David L. Crandall
Archive | 2002
Hassan Mahmound Elokdah; Geraldine Ruth Mcfarlane; David Zenan Li; Lee Dalton Jennings; David L. Crandall
Journal of Medicinal Chemistry | 2004
Hassan M. Elokdah; Theodore S. Sulkowski; Magid Abou-Gharbia; John A. Butera; Sie-Yearl Chai; Geraldine Ruth Mcfarlane; Mar-Lee McKean; John Babiak; Steven J. Adelman; Elaine Quinet
Journal of Medicinal Chemistry | 2000
Adam M. Gilbert; Madelene Antane; Thomas M. Argentieri; John A. Butera; Gerardo D. Francisco; Chris Freeden; Eric G. Gundersen; Russell Graceffa; David R. Herbst; Bradford H. Hirth; Joseph R. Lennox; Geraldine Ruth Mcfarlane; N. Wesley Norton; Dominick Anthony Quagliato; Jeffrey H. Sheldon; Dawn Warga; and Alexandra Wojdan; Morgan Woods
Archive | 2003
Hassan Mahmoud Elokdah; Geraldine Ruth Mcfarlane; David Zenan Li
Archive | 2003
Lee Dalton Jennings; Hassan Mahmoud Elokdah; Geraldine Ruth Mcfarlane
Archive | 2002
Hassan Mahmoud Elokdah; Geraldine Ruth Mcfarlane; Scott Christian Mayer; David L. Crandall
Tetrahedron Letters | 2006
Zheng Wang; Hassan M. Elokdah; Geraldine Ruth Mcfarlane; Sherry Pan; Madelene Antane
Archive | 2004
Hassan Mahmoud Elokdah; Geraldine Ruth Mcfarlane; Scott Christian Mayer
