Gerard Delmas

Selective Oxidation of Sulfides to Sulfoxides by Atmospheric Oxygen and Aldehyde Catalysed by NIII Complexes

Abstract A new and efficient method for oxidising sulfides selectively to sulfoxides has been developed with atmospheric oxygen, in the presence of isobutyraldehyde and catalysed by NiII complexes such as bis[1,3-bis-(p-methoxyphenyl)-1,3-propanedionato]nickel, [Ni(dmp)2], and bis[acetylacetonato]nickel, [Ni(acac)2].

Comparative evaluation of oxidising and nucleophilic properties of some α-nucleophiles

Six α-nucleophiles were evaluated at pH = 8 in an aqueous methanolic solution for their oxidising power towards tetrahydrothiophene, and the nucleophilic properties towards paraoxon. MMPP and m-CPBA are the most versatile reagents and can act as nucleophiles as well as oxidising agents.

Destruction of Toxic Organophosphorus Esters by Oxidative α-Nucleophilic Reagent

Abstract Despite its self-decomposition, Magnesium MonoPeroxyPhtalate 4 is an excellent reagent to totally detoxify phosphonothiolate 1 and fluoridate 2 in basic aqueous medium.

NOUVEAUX DECONTAMINANTS. DESTRUCTION DE TOXIQUES ORGANOPHOSPHORES ET SOUFRES PAR L'ACIDE MONOPEROXYPHOSPHORIQUE

Abstract H3PO5, monoperoxyphosphoric acid easily prepared by the reaction of H2O2 with P2O5 in acetonitrile, is a very good decontamination agent. The destruction of toxic sulfur and phosphorus agents is completly achieved in very short time.

Reactions of N,N-diisopropyl-2-aminoethylp-fluorobenzene thiosulfonate with oxidising agents

Abstract The behaviour of N,N -diisopropyl-2-aminoethyl p- fluorobenzene thiosulfonate 3 , which may be considered as a weakly toxic chemical analogue of VX agent, was investigated against oxidising agents. As VX 1 , this compound exhibits the same tendency to give S–S bond cleavage. Its degradation by Curox® shows the formation of the N- oxide 6 which subsequently gives the sulfonate 7 by hydrolysis. The action of hydrogen peroxide, with or without boric acid, leads to the sulfinate 4 by S-S bond cleavage. Its oxidation gives sulfonate 7 . Finally, reactions of MMPP and m- CPBA afford sulfonate 7 but no intermediates are highlighted with these reagents.