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Gerd Dannhardt

Goethe University Frankfurt

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Publication

Featured researches published by Gerd Dannhardt.

European Journal of Medicinal Chemistry | 1991

Anti-mycobacterial 4-hydroxy-3-phenylpyridin-2 (1H)-ones

Gerd Dannhardt; W Meindl; Bernt D. Schober; Thomas Kappe

4-Hydroxy-3-phenylpyridin-2 (1H)-ones with different substituents either at N-1 or in the phenyl group were synthesized by reaction of ethyl β-aminocrotonates with dialkyl malonates or ‘magic malonates’ (2,4,6-trichlorophenyl malonates). The evaluation of these compounds on Mycobacterium tuberculosis H37Ra, Escherichia coli B and Staphylococcus aureus ATCC 25923 showed significant inhibitory effects on M tuberculosis (5g and 5s, MIC = 8 μg/ml). A structure-activity relationship is discussed.

Archive | 1995

[a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF

Stefan Laufer; Hans Gunther Striegel; Gerd Dannhardt

Archive | 1995

A!-anellated pyrrole derivatives and their use in pharmacology

Stefan Laufer; Hans Gunther Striegel; Gerd Dannhardt

Archiv Der Pharmazie | 1993

Nonsteriodal Antiinflammatory Agents, XVII: Inhibition of Bovine Cyclooxygenase and 5-Lipoxygenase by N-Alkyldiphenyl-pyrrolyl Acetic and Propionic Acid Derivatives†

Gerd Dannhardt; M. Lehr

Archive | 1992

Substituted pyrrole compounds and use thereof in pharmaceutical compositions

Gerd Dannhardt; Ludwig Steindl; Matthias Lehr

Archiv Der Pharmazie | 1991

Hypertensiv wirksame 5‐(β‐Aminoethyl)aminoisoxazole: Synthese und Prüfung von Isoxazolopyrazinen und Isoxazolodiazepinen

Gerd Dannhardt; Peter Dominiak; Stefan Laufer

Archiv Der Pharmazie | 1990

Antimykobakteriell wirksame 2‐Hydroxychinolizin‐4‐one

Gerd Dannhardt; Thomas Kappe; Wolfgang Meindl; Bernt D. Schober

Archiv Der Pharmazie | 1989

Synthese von 4‐Amino‐3‐(p‐chlorphenyl)‐5‐(β‐aminoethyl)‐thioisoxazol Synthesis of 4‐Amino‐3‐(p‐chlorphenyl)‐5‐(β‐aminoethyl)‐thioisoxazole

Gerd Dannhardt; Irmengard Obergrusberger

Archiv Der Pharmazie | 1992

Untersuchungen zur Benzylierung von Tetrahydroisochinolinen mit Benzaldehyd bzw. substituierten Benzaldehyden (Rügheimer-Burrows-Reaktion)†

Gerd Dannhardt; Julius Roelcke

Archiv Der Pharmazie | 1990

Ringtransformation von Phenacyliden-pyrrolidinen: Regioselektive Bildung von 3- bzw. 5-Aminopropylisoxazolen durch Variation des Substituenten am N-Atom†

Gerd Dannhardt; Ernst Eibler; Irmengard Obergrusberger

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Stefan Laufer

Goethe University Frankfurt

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Irmengard Obergrusberger

Goethe University Frankfurt

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Thomas Kammermeier

University of Regensburg

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Thomas Kappe

University of Graz

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B. Schober

Goethe University Frankfurt

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Ernst Eibler

University of Regensburg

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Julius Roelcke

Goethe University Frankfurt

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M. Lehr

Goethe University Frankfurt

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P. Dominiak

Goethe University Frankfurt

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Bernt D. Schober

University of Graz

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