Gergely Gulyás-Fekete
University of Pécs
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Publication
Featured researches published by Gergely Gulyás-Fekete.
Bioorganic & Medicinal Chemistry | 2011
Tamás Kálai; Erzsébet Borza; Csenge Antus; Balázs Radnai; Gergely Gulyás-Fekete; Andrea Fehér; Balazs Sumegi; Kálmán Hideg
New resveratrol analogues containing five- and six-membered nitroxides and isoindoline nitroxides were synthesized. These new compounds were compared to resveratrol based on their ABTS radical scavenging ability as well on their capacity to suppress inflammatory process in macrophages induced by lipopolysaccharides. The ABTS and ROS scavenging activities of new molecules were the same or weaker than that of resveratrol, but some of paramagnetic resveratrol derivatives suppressed nitrite and TNFα production more efficiently than resveratrol. Based on these results the new nitroxide and phenol containing hybrid molecules can be considered as new antioxidant and anti-inflammatory agents.
Journal of Agricultural and Food Chemistry | 2016
Enrique Murillo; Erika Turcsi; Ildikó Szabó; Yesuri Mosquera; Attila Agócs; Veronika Nagy; Gergely Gulyás-Fekete; József Deli
The detailed carotenoid analysis of red mamey (Pouteria sapota) was achieved by HPLC-DAD-MS, chemical tests, and cochromatography with authentic samples. Altogether 47 components were detected and 34 identified from the total extract or after fractionation with column chromatography. The main carotenoids were cryptocapsin, sapotexanthin, and capsanthin 5,6-epoxide. Some further minor components containing the κ-end group with or without a hydroxy group and their 5,6-epoxy precursors were identified. Some comments are made about the biosynthesis of κ-carotenoids in red mamey.
Synthetic Communications | 2015
Györgyi Úr; Tamás Kálai; Mária Balog; Balázs Bognár; Gergely Gulyás-Fekete; Kálmán Hideg
Abstract 3-Substituted and 3,4-disubstituted pyrroline nitroxides containing an ethynyl group or two ethynyl groups were achieved by the reaction of a paramagnetic aldehydes with dimethyl (1-diazo-2-oxopropyl)phosphonate (Bestmann–Ohira reagent). The new compounds containing an ethynyl group were found to be useful building blocks in Sonogashira coupling, cyclization, and cycloaddition reactions producing potentially “azido-specific” cross-linking spin labels, paramagnetic ligands, and polyradical scaffolds. GRAPHICAL ABSTRACT
Monatshefte Fur Chemie | 2014
Tamás Kálai; Noémi Lazsányi; Gergely Gulyás-Fekete; Kálmán Hideg
We synthesized new paramagnetic retinal analogues using Horner-Wadsworth-Emmons and Wittig reactions. In these new analogues, the pyrroline nitroxide moiety is situated in the place of the β-ionone ring or at the end of the polyene chain.Graphical abstract
Journal of Natural Products | 2013
Gergely Gulyás-Fekete; Enrique Murillo; Tibor Kurtán; Tamás Papp; Tünde Zita Illyés; László Drahos; Júlia Visy; Attila Agócs; Erika Turcsi; József Deli
Helvetica Chimica Acta | 2012
Enrique Murillo; Yesury Mosquera; Tibor Kurtán; Gergely Gulyás-Fekete; Veronika Nagy; József Deli
Journal of Archaeological Science | 2011
László Márk; Gergely Gulyás-Fekete; Antónia Marcsik; Erika Molnár; György Pálfi
Helvetica Chimica Acta | 2010
Magdolna Háda; Veronika Nagy; Gergely Gulyás-Fekete; József Deli; Attila Agócs
Journal of Agricultural and Food Chemistry | 2015
Erika Turcsi; Enrique Murillo; Tibor Kurtán; Ádám Szappanos; Tünde Zita Illyés; Gergely Gulyás-Fekete; Attila Agócs; Péter Avar; József Deli
Monatshefte Fur Chemie | 2015
Imre Huber; István Zupkó; Ida Kovács; Renáta Minorics; Gergely Gulyás-Fekete; Gábor Maász; Pál Perjési