Gergely Horváth

Experimental 13.56 MHz RFID cards on biodegradable substrates

The paper presents experimental research on investigating the production and testing aspects of ISO/IEC 14443 contactless RFID tags fabricated on biodegradable cellulose acetate (CA) biopolymer-based Printed Circuit Boards (PCB). Our approach reduces the harmful plastic waste by substituting the standard materials of the cards with biodegradable substrate. Also, with common PCB fabrication methodology the prototyping and production becomes cost-effective for the novel material. The paper will detail the manufacturing steps and the different aspects of production for the prepared cards. The preliminary functional results show promising examples of a functional, standard 13.56 MHz RFID reference cards.

Engineering Support Systems for Industrial Machines and Plants

In the business of industrial machines and plants, rapid and detailed estimates for planning installation, replacement of equipment, or maintenance work are key requirements for meeting the demands for greater reliability, lower costs and for maintaining safe and secure operation. These demands have been addressed by developing technology driven by IT. When replacing equipment at complex building or plants with high equipment density, the existing state of the installation locations and transportation routes for old and new equipment need to be properly measured. We have met this need by developing parts recognition technology based on 3D measurement, and by developing high-speed calculation technology of optimal routes for installation parts. This chapter provides an overview of these development projects with some real business application results.

Investigation of P2X7R involvement in maternal poly(i:C) exposure evoked autistic features in mice

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with core symptoms of unusual social interaction and communication and increased repetitive behaviours with limited interests of environment. Recent studies have revealed that purinergic signalling (hyperpurinergia) is one of a key features of autism. Our aim was to establish a reliable model of ASD in our lab utilizing a broad range of behavioural experiments in order to investigate the role of P2X7 in autism. We injected Poly(I:C) (PIC) in two doses to pregnant C57Bl/6 mice: 3 mg/kg on E12.5 and 1.5 mg/kg on E17.5 respectively. Offsprings were weaned 4 weeks of age and behavioural studies started from 8 weeks of age. We performed social preference test, measured the body temperature and sensorymotor coordination (rotarod). We used self grooming and marble burying test in order to investigate manifestation of repetitive behaviour and measured the sensorymotor gating with Prepulse Inhibition (PPI). After behavioural experiments animals were sacrificed. Para-sagittal sections of the cerebellar vermis were cut and Purkinje cells were counted. Synaptosome fractions were made from half brains of animals and examined by electron microscopy. Striatum and Hippocampus monoamine content were measured by HPLC. We compared PIC treated offsprings with naive animals (n=10-16 animals/group). PIC treated animals showed decreased sociability and sensorymotoric coordination but we did not find change in body temperature of PIC animals. MIA animals showed increased repetitive behaviour in the marble burying and self grooming test. Quantitative Purkinje cell dropout was found in PIC mice and electron microscopy of half brain revealed ultrastructural abnormalities in them. Higher level of monoamins were detected in ASD mice compared to the control group. Based on these results this model seem to be suitable to measure the effect of different compounds or genetic deletion on PIC induced ASD symptoms in rodents.