Gert Strandlund
AstraZeneca
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Publication
Featured researches published by Gert Strandlund.
Bioorganic & Medicinal Chemistry Letters | 2014
Roine I. Olsson; Ingemar Jacobson; Tommy Iliefski; Jonas Boström; Öjvind Davidsson; Ola Fjellström; Annika Björe; Christina Olsson; Johan Sundell; Ulrik Gran; Jonna Gyll; Jesper Malmberg; Olle Hidestål; Hans Emtenäs; Tor Svensson; Zhong-Qing Yuan; Gert Strandlund; Annika Åstrand; Emma Lindhardt; Gunilla Linhardt; Elin Forsström; Ågot Högberg; Frida Persson; Birgit Andersson; Anna Rönnborg; Boel Löfberg
A series of lactam sulfonamides has been discovered and optimized as inhibitors of the Kv1.5 potassium ion channel for treatment of atrial fibrillation. In vitro structure-activity relationships from lead structure C to optimized structure 3y are described. Compound 3y was evaluated in a rabbit PD-model and was found to selectively prolong the atrial effective refractory period at submicromolar concentrations.
Journal of Computer-aided Molecular Design | 2007
Claire L. Gavaghan; Catrin Hasselgren Arnby; Niklas Blomberg; Gert Strandlund; Scott Boyer
Archive | 1998
Gert Strandlund; Christer Alstermark; Annika Björe; Magnus Björsne; Marianne Frantsi; Torbjörn Halvarsson; Kurt-Jürgen Hoffmann; Eva-Lotte Lindstedt; Magnus Polla
Archive | 2006
Annika Björe; Magnus Björsne; David Cladingboel; Kurt-Jürgen Hoffmann; John Pavey; Gert Strandlund; Peder Svensson; Colin Thomson; Michael Wilsterman
Archive | 2007
Annika Björe; Jonas Boström; Öjvind Davidsson; Hans Emtenäs; Ulrik Gran; Tommy Iliefski; Johan Kajanus; Roine I. Olsson; Lars Sandberg; Gert Strandlund; Johan Sundell; Zhong-Qing Yuan
Archive | 2001
Magnus Björsne; Kurt-Jürgen Hoffmann; Gert Strandlund; Peder Svensson; Michael Wilstermann
Archive | 2000
Magnus Björsne; Gert Strandlund; Peder Svensson
Archive | 2003
Kjell H. Andersson; Annika Björe; Magnus Björsne; Gert Strandlund; Peder Svensson; Louise Tottie
Archive | 2000
Annika Björ; Magnus Björsne; Torbjörn Halvarsson; Kurt-Jürgen Hoffmann; Bertil Samuelsson; Gert Strandlund
Archive | 2006
Annika Björe; David Cladingboel; Gareth AstraZeneca R D Charnwood Ensor; Adam Herring; Johan Kajanus; Robert Lundqvist; Christina Olsson; Carl-Gustav Sigfridsson; Gert Strandlund
