Gilberto Neri

P-649: Prevalence and controll of cardiovascular risk factors in a tertiary hypertension clinic

according to the formula: LDL5CHL-(HDLcholesterol1 Triglicerides/5). All the patients did not assume any antidyslipidemic treatment. Mean sphygmomanometric blood pressure was: 150 1/-19/901/-10 mmHg; mean PP was: 60 1/-15 mm Hg and heart rate: 72 1/-12 beats/ min. Total-cholesterol, HDL-cholesterol, Triglicerides and LDL-cholesterol were: 2251/-37 mg/dl, 561/-15 mg/dl, 1431/-61 mg/dl and 1401/-34 mg/dl, respectively. A significant correlation was observed between PP and LDL-cholesterol (linear regression analysis; r 5 0.21, p,.02), whereas the correlation between PP and Total-cholesterol, and between PP and HDL-cholesterol did not reach a statistical significance (r5 0.17, p5.07; r5 0.13, p5.18, respectively). In conclusion, in the population studied of resistant hypertensive patients, the correlation found between pulse pressure and LDL-cholesterol suggests that, in presence of persistently elevated blood pressure, plasma lipids may influence the vascular stiffness, expressed by pulse pressure values. Possibly, the vascular alterations linked to dyslipidemia may account for resistence versus pharmacological therapy.