Godefroy Koki

Central corneal thickness and intraocular pressure in the Cameroonian nonglaucomatous population

Aim: We performed a prospective, analytical study from 01 January to 31 March 2009 in the Ophthalmology Unit of the Gyneco-Obstetric and Pediatric Hospital of Yaounde, aiming to determine the profile of central corneal thickness (CCT) in the Cameroonian nonglaucomatous black population and its relationship with intraocular pressure (IOP). Results and discussion: Four hundred and eighty-five patients (970 eyes) meeting our inclusion criteria were selected for this study. The average CCT was 529.29 ± 35.9 μm in the right eye (95% confidence interval [CI]: 526.09–532.49), 528.19 ± 35.9 μm in the left eye (95% CI: 524.99–531.40) and 528.74 ± 35.89 μm in both eyes (95% CI: 526.48–531.00), range 440 to 670 μm. The average IOP was 13.01 ± 2.97 mmHg in both eyes (95% CI: 12.82–13.19). A rise in CCT by 100 μm was followed by an increase in IOP of about 2.8 mmHg (95% CI: 2.3–3.6) for both eyes taken together. Linear regression analysis showed that corneal thickness was negatively correlated with age and IOP was positively related with age. Conclusion: CCT in the Cameroonian nonglaucomatous black population was found to be lower compared with CCT values in Caucasian and Asian populations. On the basis of reference values ranging between 527 and 560 μm, an adjustment of IOP values by a correction factor is required for many Cameroonian patients. This will improve the diagnosis and follow-up of glaucoma by helping to detect true ocular hypertension.

Unilateral childhood blindness: a hospital-based study in Yaoundé, Cameroon

Introduction: We performed an analytic and prospective study over a period of 12 months from January 2nd to December 31st, 2008, at the Gynaeco-Obstetric and Paediatric Hospital of Yaoundé, Cameroon. Our aim was to determine the prevalence and causes of unilateral blindness in school children aged 6 to 15 years. Results: Among the 1,266 children aged 6 to 15 years who were recruited, 60 presented with unilateral blindness (4.7%): 42 boys (6.96%) and 18 girls (2.71%). The mean age was 10.15 ± 3.4 years. In patients with unilateral blindness, 65% was due to ocular trauma. Discussion: The hospital-based prevalence of unilateral blindness in children is relatively high and ocular trauma is the leading etiology. Conclusion: Unilateral blindness in school children is avoidable and its incidence could be markedly reduced by emphasizing an information strategy and education based on prevention of ocular trauma. Early management of nontraumatic diseases such as infantile glaucoma and some tumors could improve outcome and avoid blindness.

Prevalence and causes of blindness at a tertiary hospital in Douala, Cameroon.

Purpose The aim of this study was to determine the prevalence and causes of bilateral and unilateral blindness in the town of Douala and its environs based on data from the ophthalmic unit of a tertiary hospital in Douala. Methods We conducted a retrospective epidemiological survey of consultations at the eye unit of the Douala General Hospital over the last 20 years (from January 1, 1990 to December 31, 2009). Results Out of the 1927 cases of blindness, 1000 were unilateral, corresponding to a hospital prevalence of 1.84% and 927 cases were bilateral, corresponding to a hospital prevalence of 1.71%. No statistically significant difference was noted between the two (P = 0.14). The leading causes of bilateral blindness were cataract (50.1%), glaucoma (19.7%), and diabetic retinopathy (7.8%) while the leading causes of unilateral blindness were cataract (40.4%), glaucoma (14.1%), and retinal detachment (9.1%). Cataract (51.2%), cortical blindness (16.3%), and congenital glaucoma (10%) were the leading causes of bilateral blindness in children aged less than 10 years. Conclusion Blindness remains a public health problem in the Douala region with a hospital prevalence which is relatively higher than the national estimate given by the National Blindness Control Program.

Indications for destructive eye surgeries at the Yaounde Gynaeco-Obstetric and Paediatric Hospital.

Objective: To determine the indications and rate of acceptance for destructive eye surgeries at the ophthalmology unit of the Yaoundé Gynaeco-Obstetric and Paediatric Hospital. Methods: A retrospective consecutive case series in which the medical records of all patients consulting in this unit over a 9-year period (2002 to 2010) were reviewed. Records in which destructive surgery was recommended were retained. Information collected included demographic data, eye affected, clinical diagnosis, acceptance or refusal of surgery, and the outcome in those in whom surgery was performed. Results: A total of 48 patients had a recommendation for destructive eye surgery, of whom 30 (62.5%) were males and 18 (37.5%) were females. Mean age was 43.78 (SD = 28.11; range 1 month to 91 years). Children <10 years comprised 23.10%. The leading causes were endophthalmitis/panophthalmitis (47.9%), neoplasm (20.8%), and absolute glaucoma (14.6%). Surgery was done in 20 cases (41.7%). Evisceration was the most performed surgical procedure (50%), with endophthalmitis/panophthalmitis and neoplasm combined accounting for 65% of surgeries. Conclusion: The high rate of refusal is an indication of the psychological devastation undergone by patients or the families of children in whom eye removal is recommended. Awareness should be raised on preventive measures and the need to rapidly seek eye care.

Intraocular live male filarial Loa loa worm.

We report a case of Loa loa filariasis in an 8-month-old child who presented with a 3-month history of irritated acute red eye and insomnia. Examination revealed a living and active adult Loa loa worm in the anterior chamber of the left eye. The worm was extracted under general anesthetic.

Blindness and visual impairment in retinitis pigmentosa: a Cameroonian hospital-based study.

Aim: We performed a retrospective, analytical study in February 2010 on all retinitis pigmentosa cases seen during ophthalmologic consultation at the Gyneco-Obstetrics and Pediatric Hospital of Yaounde between March 2002 and December 2009 (82 months). The aim of this research was to determine the significance of blindness and visual impairment associated with retinitis pigmentosa in Cameroon. Results: Forty cases were reported, corresponding to a hospital prevalence of 1.6/1000 (21 men and 19 women). The average age of the patients was 43.3 ± 18 years, ranging between 6 and 74 years. Bilateral blindness and low vision was noted in 30% and 27.5% of patients, respectively. The average age of patients with low vision was 40.38 ± 16.27 years and the average age of those with bilateral blindness was 51.08 ± 15.79 years. Retinitis pigmentosa was bilateral in all cases and isolated (without any eye or general additional disease) in 67.5% of cases. Conclusion: Visual impairment is common and becomes even more severe with aging. Patients should be screened to enable them to benefit from management focusing on both appropriate treatment and genetic counseling.

Eye malformations in Cameroonian children: a clinical survey.

Summary The aim of this work was to describe the clinical aspects of eye malformations observed at the ophthalmology unit of the Yaoundé Gynaecology, Obstetrics and Pediatrics Hospital. Patients and methods We carried out a retrospective study of all malformations of the eye and its adnexae observed among children aged 0–5 years who were seen at the ophthalmology unit from January 2003 to December 2009. Results Out of the 2254 children who were examined, 150 (6.65%) presented eye malformations. The mean age was 14.40 ± 4 months. Eye malformations were diagnosed in 71.66% of cases during the first year of life. The most frequent malformations were congenital lacrimal duct obstruction (66.66%), congenital cataract (10.9%), congenital glaucoma (10.9%), microphthalmos (5.03%), and congenital ptosis (3.77%). Conclusion Eye malformations among children can lead to visual impairment and are a cause for discomfort to children and parents. Therefore, systematic postnatal screening is recommended to enable early management.

La limboconjonctivite endémique des tropiques au nord Cameroun

INTRODUCTION A retrospective study was conducted in the ophthalmology unit of the Garoua regional hospital on children examined from January 2001 to December 2007. We aimed to determine the epidemiological aspects of tropical endemic limboconjunctivitis in northern Cameroon. Included were all the files of patients aged 0-15 years seen with a positive diagnosis of tropical endemic limboconjunctivitis. The data analyzed were obtained through inspection, interview, and a comprehensive ocular exam done for every case, assessing far visual acuity, slit lamp biomicroscopy, and funduscopy when possible. The variables analyzed were age, sex, signs and symptoms, residential area, associated pathologies, and the month and the year of the diagnosis. The data were analyzed with Epi-Info, version 6.04d (French) and the results compared with the Chi(2) test with a 95% confidence interval. RESULTS A total of 6453 children were included: 2036 had a positive diagnosis of tropical endemic limboconjunctivitis, with a frequency of 31.55%. The mean age was 6.5 years. The 1- to 4-year-old age group had the highest number of patients, with a frequency of 33.25%. There were 1120 males (55%). Itching was the most frequent complaint encountered in 60.90% of the patients. Ocular involvement was always bilateral. Tropical endemic limboconjunctivitis is an allergic conjunctivitis present throughout the year with two peaks in March and July. DISCUSSION Tropical endemic limboconjunctivitis can be considered an allergic conjunctivitis affecting boys more frequently than girls in warm and dry environments. It is frequent in children less than 5 years old and regresses with age. CONCLUSION Tropical endemic limboconjunctivitis is a tropical disease with an intertropical aspect.

Analysis of central corneal thickness in black Cameroonian children

Correspondence: Andre Omgbwa Eballe Department of Ophthalmology, gynaeco-Obstetric and Pediatric hospital of Yaounde, PO Box 4362, Yaounde, Cameroon Tel +237 9965 4468 Fax +237 2221 2430 Email andyeballe@gmail.com Purpose: Our objective was to determine mean pediatric central corneal thickness (CCT) in black Cameroonian children, according to gender and age, using ultrasonic pachymetry. Materials and methods: A prospective, observational, consecutive case series in 102 children (204 eyes) aged 5–16 years was carried out from November 2009 to January 2010 at the Eye Unit of the Gynaeco-Obstetric and Paediatric Hospital in Yaounde, Cameroon. Descriptive and analytic statistics were performed for CCT measured by a hand-held ultrasonic pachymeter (Quantel Medical Inc, Clermont-Ferrand France, Model Pocket, Class II) according to demographic data. Results: The average CCT for both eyes in these children was 538.06 ± 38.03 μm. Average CCT was 541.41 ± 36.45 μm in boys and 536.15 ± 38.91 μm in girls, with no statistically significant difference between the two groups. There was also no statistically significant difference in CCT between the age groups, comprising Group 1 (5–7 years), Group 2 (8–10 years), Group 3 (11–13 years), and Group 4 (14–16 years). Conclusion: CCT has been suggested to be lower in black children than in Caucasian, Hispanic, and Japanese children. Nevertheless, our average CCT values were within the standard range, varying between 527 and 560 μm.

Les traumatismes oculaires en milieu urbain camerounais : à propos de 332 cas évalués selon l’Ocular Trauma Score☆

PURPOSE To determine the epidemiologic and clinical characteristics of ocular trauma after evaluation with the ocular trauma score at the Army Teaching Hospital in Yaoundé, Cameroon. PATIENTS AND METHODS A descriptive and retrospective monocentric hospital study was carried out from January 2008 to December 2010. Our sample included all patients with ocular trauma. Each traumatized eye was evaluated using the ocular trauma score after measurement of visual acuity. The most severe diagnoses observed were classified according to the Birmingham Eye Trauma Terminology system. RESULTS The frequency out of 364 eyes was 3.56%. There were 204 men (61.44%) with a male/female ratio of 1.59. The mean age was 32.95 years with predominance of 21-30 years. The most affected groups were laborers and craftsmen (28.61%), followed closely by students (23.80%), then armed forces personnel (19.58%). Fights were noted as the most common cause in 31.02% of cases. Punches predominated in 21.39% of cases. In 37.34% of cases, patients were seen within 72 hours of the trauma. Three hundred (90.36%) traumas were unilateral vs. 32 (9.64%) bilateral. The mean visual acuity at the first consultation was 0.3 logMAR. Grading after evaluation was as follows, 13 eyes were grade 1, 19 grade 2, 25 grade 3, 54 grade 4 and 253 grade 5. Fragile and exposed anatomical structures were the most commonly injured. Seventeen eyes exhibited elevated IOP (22 to 45) vs. 7 which were hypotonous. Two hundred and one (55.22%) oculo-palpebral contusions were noted, followed by 110 (30.22%) lacerations. Visual loss was reported in 16.20% and blindness in 8.79% of cases. CONCLUSION In the emergent setting, a good, timely clinical evaluation of each case according to the ocular trauma score may lead to effective management.