Gordon E. Bearse

Strain Differences in Mercury Retention by Chicks.

Summary Studies made with 3 strains of chicks showed one strain to be significantly different in retention of mercury in liver and kidneys, following intramuscular injections of phenylmercury acetate or mercuric chloride. Differences following injection of equivalent amounts of mercury as ethylmercury chloride or Salyrgan were much less. Mercury retention was greater in the strain selected for resistance to lymphomatosis than in the 2 susceptible strains which showed little difference.

ALL-OR-NONE TRAITS AND THE SENSITIVITY OF EXPERIMENTS.

THE choice of the strain of laboratory animal has been examined by Chai1, by Biggers, McLaren and Michie2, and by Becker3. Much of the discussion in these papers involved the choice of mice of inbred strains or those of the F1 generation for bioassay. In addition, Becker and Berg4–6 have reported tests which were designed to determine which sex and strain of chickens produced the most sensitive nutritional experiments.

Differences in copper retention in two strains of chickens.

Abstract Cupric acetate was injected intramuscularly in two strains of chickens developed by selection for a difference in susceptibility to the avian leukosis complex. When given a dose of 9.1 mg copper per kilogram of body weight as cupric acetate, one strain retained significantly more copper in the liver than the other strain. However, when injected with a dose of 0.91 mg copper per kilogram of body weight as cupric acetate no differences were observed.