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Dive into the research topics where Goverdhan Gilla is active.

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Featured researches published by Goverdhan Gilla.


Synthetic Communications | 2008

Alternative Synthesis of Tadalafil: PDE5 Inhibitor

Raghupathi Reddy Anumula; Lokeswara Rao Madivada; Goverdhan Gilla; V.V.N.K.V Prasad Raju; Mukkanti Kagga; Padi Pratap Reddy; Apurba Bhattacharya; Rakeshwar Bandichhor

Abstract Two-step alternative synthesis of tadalafil (1) is described. The synthesis features Pictet–Spengeler type reaction and DCC (N,N′-dicyclohexylcarbodiimide)/HOBt (N-hydroxybenzotriazole)–mediated double amidation employing sarcosine ethyl ester hydrochloride.


RSC Advances | 2016

Highly enantioselective bioreduction of 1-(3,4-difluorophenyl)-3-nitropropan-1-one: key intermediate of ticagrelor

Manpreet Singh; Hare Krishnen; Uday Kumar Neelam; Kavitha Charugondla; Goverdhan Gilla; Karen Holt-Tiffin; Rakeshwar Bandichhor

A simple, highly effective and economical whole-cell mediated process was developed for the biocatalytic reduction of a ketone, intermediate in the synthesis of platelet inhibiting drug ticagrelor. Sixteen different microorganisms were screened for the bioreduction of 1-(3,4-difluorophenyl)-3-nitropropan-1-one (1) to (S)-1-(3,4-difluorophenyl)-3-nitropropan-1-ol (2). Growing as well as resting cells of Candida parapsilosis 104659 exhibited high conversion (>99.0%) and enantioselectivity (98.0%) for the S-enantiomer.


Archive | 2007

Process for preparing solifenacin and its salts

Vijayavitthal T. Mathad; Goverdhan Gilla; Sriramireddy Kikkuru; Raveendra Reddy Chinta; Swaroopa Dudipala


Archive | 2013

Preparation of ticagrelor

Vilas H. Dahanukar; Goverdhan Gilla; Sreenivasulu Kurella; Shweta Mahajan Kulkarni; Raghupathi Reddy Anumula; Sampath Aalla; Yakambram Bojja; Ravi Ram Chandrasekhar Elati; Veerender Murki; Venkata Annapurna Sasikala Cheemalapati


Organic Process Research & Development | 2009

An Improved Process for Pioglitazone and Its Pharmaceutically Acceptable Salt

Lokeswara Rao Madivada; Raghupathi Reddy Anumala; Goverdhan Gilla; Sampath Alla; Kavitha Charagondla; Mukkanti Kagga; Apurba Bhattacharya; Rakeshwar Bandichhor


Archive | 2007

PROCESS FOR PREPARING CLOPIDOGREL

Eswaraiah Sajja; Raghupathi Reddy Anumula; Goverdhan Gilla; Lokeswara Rao Madivada


Organic Process Research & Development | 2012

Process Improvements of Prasugrel Hydrochloride: An Adenosine Diphosphate Receptor Antagonist

Sampath Aalla; Goverdhan Gilla; Dattatray S. Metil; Raghupathi Reddy Anumula; Prabhaker Reddy Vummenthala; Pratap Reddy Padi


Organic Process Research & Development | 2012

An Efficient and Telescopic Process for Valsartan, an Angiotensin II Receptor Blocker†

Sampath Aalla; Goverdhan Gilla; Yakambram Bojja; Raghupathi Reddy Anumula; Prabhakar Reddy Vummenthala; Pratap Reddy Padi


Archive | 2008

PROCESS FOR PREPARATION OF CELECOXIB

Raghupathi Reddy Anumula; Goverdhan Gilla; Sampath Alla; Thirupathi Reddy Akki; Yakambram Bojja


Archive | 2013

Process for preparation of abiraterone acetate

Vilas Hareshwar Dahanukar; Goverdhan Gilla; Syam Kumar Unniaran Kunhimon; Nageshwar Gunda; Venkata Rao Badisa; Shravankumar Komati; Srinivas Benda; Tridib Mahapatra

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Sampath Aalla

Dr. Reddy's Laboratories

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Sampath Alla

Dr. Reddy's Laboratories

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