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Gp Zara

University of Turin

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Publication

Featured researches published by Gp Zara.

Biomedical Chromatography | 2000

Determination of Ibuprofen in human plasma by high-performance liquid chromatography: validation and application in pharmacokinetic study.

Roberto Canaparo; Elisabetta Muntoni; Gp Zara; C. Della Pepa; E. Berno; M Costa; Mario Eandi

A specific method for the simultaneous determination of S-(+)Ibuprofen and R-(-)Ibuprofen enantiomers in human plasma is described. Adopting a high-performance liquid chromatographic (HPLC) system with spectrofluorometer detector, the compounds were extracted from plasma in alcohol medium and were separated on C18 column, using a solution of acetonitrile-water-acetic acid-triethylamine as mobile phase. The limit of quantitation was 0.1 microg/mL for both compounds. The method was validated by intra-day assays at three concentration levels and was used in a kinetic study in healthy volunteers. During the study we carried out inter-day assays to confirm the feasibility of the method.

Biomedical Chromatography | 2002

Simultaneous HPLC determination of 5-fluorouracil and its metabolites in plasma of cancer patients

Federico Casale; Roberto Canaparo; Elisabetta Muntoni; Loredana Serpe; Gp Zara; C. Della Pepa; E. Berno; M Costa; Mario Eandi

British Journal of Clinical Pharmacology | 2000

Plasma erythropoietin concentrations in patients receiving intensive platinum or nonplatinum chemotherapy

Roberto Canaparo; Federico Casale; Elisabetta Muntoni; Gp Zara; C. Della Pepa; E. Berno; N. Pons; Gianni Fornari; Mario Eandi

Journal of Chromatography B | 2004

Determination of disodium clodronate in human plasma and urine using gas-chromatography-nitrogen-phosphorous detections : validation and application in pharmacokinetic study

Elisabetta Muntoni; Roberto Canaparo; C. Della Pepa; Loredana Serpe; Federico Casale; S. Barbera; P Romano; Gp Zara; Mario Eandi

The Pharmacologist | 2002

Single dose intramuscolar pharmacokinetics and local tolerability of three different disodium clodronate formulations in healthy volunteers

Mario Eandi; C. Della Pepa; Elisabetta Muntoni; Roberto Canaparo; P Romano; Federico Casale; Loredana Serpe; Gp Zara

Annals of Oncology | 2002

Plasma concentrations of 5-Fluorouracil and its metabolites in colon cancer patients

Federico Casale; C. Della Pepa; Roberto Canaparo; Elisabetta Muntoni; Loredana Serpe; Gp Zara; Lorenza Mairone; Gianni Fornari; Mario Eandi

British Journal of Clinical Pharmacology | 2000

Pharmacokinetics of disodium clodronate after single intravenous or intramuscolar injection in healthy volunteers

nullDella Pepa Nullc; Elisabetta Muntoni; Roberto Canaparo; P Romano; F Dosio; Gp Zara; Mario Eandi

British Journal of Clinical Pharmacology | 2000

HPLC determination of 5-FU and three metabolites in the plasma of cancer patients

Roberto Canaparo; Elisabetta Muntoni; Loredana Serpe; C. Della Pepa; Gp Zara; Federico Casale; Mario Eandi

Pharmacological Research | 1999

Plasma immunoerythropoietin levels in patients with cancer receiving platin-based or 5-Fluorouracil-based chemotherapy

Roberto Canaparo; N. Pons; Federico Casale; Elisabetta Muntoni; Gianni Fornari; Gp Zara; C. Della Pepa; Mario Eandi

International ICSC Congress on Computational Intelligence Methods and Applications CIMA'99 | 1999

Prediction of individual plasma concentration from population data by the Parzen method

M. Costa; E. Berno; Roberto Canaparo; Gp Zara; C. Della Pepa; Mario Eandi

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Mario Eandi

University of Turin

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C. Della Pepa

University of Turin

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Roberto Canaparo

University of Turin

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Elisabetta Muntoni

University of Turin

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Federico Casale

University of Turin

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E. Berno

University of Turin

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Loredana Serpe

University of Turin

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N. Pons

University of Turin

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S. Barbera

University of Turin

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