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Dive into the research topics where Gph Leung is active.

Publication


Featured researches published by Gph Leung.


British Journal of Pharmacology | 2009

Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells

Sai Wang Seto; Als Au; Tsz Yan Lam; Stephen Siu Chung Chim; Simon Ming-Yuen Lee; S Wan; D C S Tjiu; N Shigemura; Anthony P.C. Yim; Shun-Wan Chan; Stephen Kwok-Wing Tsui; Gph Leung; Yiu Wa Kwan

Statins (3‐hydroxy‐3‐methyl‐glutaryl coenzyme A (HMG CoA) reductase inhibitors) have been demonstrated to reduce cardiovascular mortality. It is unclear how the expression level of HMG CoA reductase in cardiovascular tissues compares with that in cells derived from the liver. We hypothesized that this enzyme exists in different cardiovascular tissues, and simvastatin modulates the vascular iberiotoxin‐sensitive Ca2+‐activated K+ (BKCa) channels.


British Journal of Pharmacology | 2008

Kaempferol stimulates large conductance Ca2+‐activated K+ (BKCa) channels in human umbilical vein endothelial cells via a cAMP/PKA‐dependent pathway

Yan Chun Xu; Gph Leung; P. Y. D. Wong; Paul M. Vanhoutte; Ricky Y. K. Man

Kaempferol has been shown to possess a vasodilator effect but its mechanism of action remains unclear. In this study, experiments were carried out to study the effect of kaempferol on K+ channels in endothelial cells.


Archive | 2009

Role of extracellular signal-related kinases in the pathophysiology of vascular dysfunction in aging and hypertension

Sws Leung; Yw Ho; Gsk Man; Gph Leung; Ryk Man

This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009


Archive | 2009

Effects of antiviral nucleoside analogs on relaxation of rat basilar arteries

Rws Li; Gph Leung

This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009


Archive | 2009

Diabetes- and hypertension-induced upregulation of concentrative nucleoside transporter-2 in endothelial cells

Gph Leung; Yw Ho; Sai Wang Seto; Yiu Wa Kwan

This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009


Archive | 2009

Possible role of organic cation transpporter-3 in serotonin uptake in human brain vascular smooth muscle cells

Yw Ho; Pmgr Vanhoutte; Ryk Man; Sws Leung; Gph Leung

This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009


Archive | 2009

Rapid, non-genomic vascular actions of genistein involves a G-protein coupled receptor

Ahy Lin; Gph Leung; Sws Leung; Ryk Man

This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009This free access journal suppl. is Proceedings of the 10th International Symposium on Mechanisms of Vasodilatation 2009


Archive | 2005

Effect of thiazolidinediones on adenosine transport in vascular smooth muscle cells

Gph Leung; Cm Tse; Ryk Man

This free online access journal suppl. entitled: Mechanisms of Vasodilatation and Endothelium-Derived Hyperpolarizing Factors (EDHF)


Archive | 2009

Lipid emulsion infusion vs standard cardiac resuscitation in management of ropivacaine cardiac toxicity in pigs

Cy Wat; Mk Yuen; Gph Leung; Jkf Ng


Archive | 2006

Prostanoid synthases and receptors in aorta of spontaneously hypertensive rat

Hc Tang; Gph Leung; Acy Lo; Sk Chung; Ryk Man; Pm Vanhoutte

Collaboration


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Yiu Wa Kwan

The Chinese University of Hong Kong

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Yw Ho

United Christian Hospital

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Hc Tang

University of Hong Kong

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Als Au

The Chinese University of Hong Kong

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Anthony P.C. Yim

The Chinese University of Hong Kong

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D C S Tjiu

Hong Kong Polytechnic University

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N Shigemura

The Chinese University of Hong Kong

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P. Y. D. Wong

The Chinese University of Hong Kong

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