Graciela Y. Moltrasio Iglesias

Hydrogenation of (-)-menthone, (+)-isomenthone, and (+)-pulegone with platinum/tin catalysts

The hydrogenation of (-)-menthone, (+)-isomenthone, and (+)-pulegone over SiO2-supported Pt and Pt-Sn catalysts was studied in this work. The modification with tin was performed by means of the techniques of surface organometallic chemistry on metals. This way of modifying the catalysts allowed stereoisomers of menthol to be obtained in a one-step process. The hydrogenation of these terpenones was favored by the presence of tin in the bimetallic phase.

Structure and stereochemistry of cyclodimers obtained by acid treatment of trans-stilbenes and of N-1,2-diarylethylamides

The reaction of trans-stilbenes and N-1,2-diarylethylamides with ethyl polyphosphate affords indanes and tetralins with three stereogenic centres. The structural and configurational assignment of the cyclodimers is based mainly on the NMR and MS data. A possible transition state for the reaction is discussed.

A Simple Synthetic Route to Pterosin F and Other Pterosins

A simple method for the preparation of pterosin F is described in which the key step involves a tandem reaction of Friedel–Crafts acylation–cycloalkylation between 2,6-dimethylphenethyl chloride and ethyl methacrylate.

CYCLIZATION PROCEDURES TOWARD THE SYNTHESIS OF SOME CONFORMATIONALLY RESTRICTED NITROGEN HETEROCYCLES

Se intento la sintesis de heterociclos nitrogenados conformacionalmente restringidos por medio de la reaccion de Bischler-Napieralski y la modificacion de Tsuda. Los resultados observados nos han llevado a especular sobre la naturaleza de los efectos que controlan el proceso de ciclacion

Synthesis and Structure of 7-Methyl-2-(4′-methyl-2′,3′-dihydro-1′H-inden-1′-yl)-1H-indene

We report research to find better conditions for the dehydration of 4-methylindan-1-ol to render 4-methylindene and 7-methyl-2-(4′-methyl-2′,3′-dihydro-1′H-inden-1′-yl)-1H-indene.

Diastereoisomeric 1-Benzyl-2,3-diphenylindanes: Stereodirected Synthesis and NMR Spectra

The stereodirected synthesis of the four racemic diastereoisomeric 1-benzyl-2,3-diphenylindanes is presented together with 1H and 13C NMR data.

Regio- and Stereo-chemical Study of the Diels–Alder Reaction between (E)-3,4-Dimethoxy-β-nitrostyrene and 1-(Trimethylsilyloxy)buta-1,3-diene

The Diels–Alder addition of 1 to 2 under thermal and Lewis acid-catalysed conditions gives the regiostereoisomers 3, the structures of which are deduced by NMR analysis; only the thermal reaction is of any preparative value and semi-empirical calculations are developed in an attempt to discover the dominant factors influencing the ortho–meta orientation.