Greg D. Reynolds

Infant Attention and Visual Preferences: Converging Evidence From Behavior, Event-Related Potentials, and Cortical Source Localization

In this study, we had 3 major goals. The 1st goal was to establish a link between behavioral and event-related potential (ERP) measures of infant attention and recognition memory. To assess the distribution of infant visual preferences throughout ERP testing, we designed a new experimental procedure that embeds a behavioral measure (paired comparison trials) in the modified-oddball ERP procedure. The 2nd goal was to measure infant ERPs during the paired comparison trials. Independent component analysis (ICA) was used to identify and to remove eye-movement components from the electroencephalographic data, thus allowing for the analysis of ERP components during paired comparison trials. The 3rd goal was to localize the cortical sources of infant visual preferences. Equivalent current dipole analysis was performed on the ICA components related to experimental events. Infants who demonstrated novelty preferences in paired comparison trials demonstrated greater amplitude Negative central ERP components across tasks than infants who did not demonstrate novelty preferences. Visual preference also interacted with attention and stimulus type. The cortical sources of infant visual preferences were localized to inferior and superior prefrontal cortex and to the anterior cingulate cortex.

The Neural Bases of Infant Attention

The development of attention in the infant can be characterized by changes in overall arousal (attentiveness) and by changes in attention’s effect on specific cognitive processes (e.g., stimulus orienting, spatial selection, recognition memory). These attention systems can be identified using behavioral and psychophysiological methods. The development of infant attention is thought to be closely related to changes in the neural systems underlying attention control. The recent application of cortical source analysis of event-related potentials (ERP) and structural magnetic resonance imaging (MRI) has led to the identification of some of these the neural systems.

The Development of Attention Systems and Working Memory in Infancy

In this article, we review research and theory on the development of attention and working memory in infancy using a developmental cognitive neuroscience framework. We begin with a review of studies examining the influence of attention on neural and behavioral correlates of an earlier developing and closely related form of memory (i.e., recognition memory). Findings from studies measuring attention utilizing looking measures, heart rate, and event-related potentials (ERPs) indicate significant developmental change in sustained and selective attention across the infancy period. For example, infants show gains in the magnitude of the attention related response and spend a greater proportion of time engaged in attention with increasing age (Richards and Turner, 2001). Throughout infancy, attention has a significant impact on infant performance on a variety of tasks tapping into recognition memory; however, this approach to examining the influence of infant attention on memory performance has yet to be utilized in research on working memory. In the second half of the article, we review research on working memory in infancy focusing on studies that provide insight into the developmental timing of significant gains in working memory as well as research and theory related to neural systems potentially involved in working memory in early development. We also examine issues related to measuring and distinguishing between working memory and recognition memory in infancy. To conclude, we discuss relations between the development of attention systems and working memory.

Neural correlates of intersensory processing in 5-month-old infants

Two experiments assessing event-related potentials in 5-month-old infants were conducted to examine neural correlates of attentional salience and efficiency of processing of a visual event (woman speaking) paired with redundant (synchronous) speech, nonredundant (asynchronous) speech, or no speech. In Experiment 1, the Nc component associated with attentional salience was greater in amplitude following synchronous audiovisual as compared with asynchronous audiovisual and unimodal visual presentations. A block design was utilized in Experiment 2 to examine efficiency of processing of a visual event. Only infants exposed to synchronous audiovisual speech demonstrated a significant reduction in amplitude of the late slow wave associated with successful stimulus processing and recognition memory from early to late blocks of trials. These findings indicate that events that provide intersensory redundancy are associated with enhanced neural responsiveness indicative of greater attentional salience and more efficient stimulus processing as compared with the same events when they provide no intersensory redundancy in 5-month-old infants.

Infant visual attention and object recognition.

This paper explores the role visual attention plays in the recognition of objects in infancy. Research and theory on the development of infant attention and recognition memory are reviewed in three major sections. The first section reviews some of the major findings and theory emerging from a rich tradition of behavioral research utilizing preferential looking tasks to examine visual attention and recognition memory in infancy. The second section examines research utilizing neural measures of attention and object recognition in infancy as well as research on brain-behavior relations in the early development of attention and recognition memory. The third section addresses potential areas of the brain involved in infant object recognition and visual attention. An integrated synthesis of some of the existing models of the development of visual attention is presented which may account for the observed changes in behavioral and neural measures of visual attention and object recognition that occur across infancy.

Brain-behavior relations in infancy: integrative approaches to examining infant looking behavior and event-related potentials.

This article describes three approaches to conducting integrated research on brain–behavior relations in infancy. These approaches include: conducting an integrative study that tests the same cognitive construct using behavioral and event-related potential (ERP) measures in separate experiments, measuring behavior and ERPs in different phases of the same experiment, and measuring behavior and ERPs simultaneously. We review studies that have utilized these approaches with a specific focus on research on infant visual attention and recognition memory, and discuss the application of cortical source localization with infant ERP data. Advantages and disadvantages of each approach are discussed and suggestions are made for future research.

Modified prenatal sensory stimulation influences postnatal behavioral and perceptual responsiveness in bobwhite quail chicks (Colinus virginianus)

Asynchronous bimodal stimulation during prenatal development elicits higher levels of behavioral and physiological arousal in precocial avian embryos than does unimodal sensory stimulation. To investigate whether the increased arousal associated with prenatal bimodal stimulation has enduring effects into postnatal development, bobwhite quail (Colinus virginianus) embryos received no supplemental stimulation, unimodal auditory stimulation, or bimodal (audiovisual) stimulation prior to hatching. Embryos exposed to concurrent bimodal stimulation demonstrated greater levels of behavioral activity and failed to use maternal visual cues to successfully direct species-specific perceptual preferences following hatching. These results provide initial evidence that asynchronous bimodal sensory stimulation during prenatal development can have enduring effects on early postnatal behavioral arousal and perceptual responsiveness and suggest that developmental limitations on prenatal sensory stimulation play an important role in the emergence of species-typical behavior.

The effects of stimulus symmetry on hierarchical processing in infancy

The current study investigated the effects of stimulus symmetry on the processing of global and local stimulus properties by 6-month-old short- and long-looking infants through the use of event-related potentials (ERPs). Previous research has shown that individual differences in infant visual attention are related to hierarchical stimulus processing, such that short lookers show a global processing bias, while long lookers demonstrate a local processing bias (Guy, Reynolds, & Zhang, 2013). Additional research has shown that in comparison with asymmetry, symmetry is associated with more efficient stimulus processing and more accurate memory for stimulus configuration (Attneave, 1955; Perkins, 1932). In the current study, we utilized symmetric and asymmetric hierarchical stimuli and predicted that the presence of asymmetry would direct infant attention to the local features of stimuli, leading short lookers to regress to a local processing strategy. Results of the ERP analysis showed that infants familiarized with a symmetric stimulus showed evidence of global processing, while infants familiarized with an asymmetric stimulus did not demonstrate evidence of processing at the global or local level. These findings indicate that short- and long-looking infants, who might otherwise fail to process global stimulus properties due to limited visual scanning, may succeed at global processing when exposed to symmetric stimuli. Furthermore, stimulus symmetry may recruit selective attention toward global properties of visual stimuli, facilitating higher-level cognitive processing in infancy.

The Development of Attentional Biases for Faces in Infancy: A Developmental Systems Perspective

We present an integrative review of research and theory on major factors involved in the early development of attentional biases to faces. Research utilizing behavioral, eye-tracking, and neuroscience measures with infant participants as well as comparative research with animal subjects are reviewed. We begin with coverage of research demonstrating the presence of an attentional bias for faces shortly after birth, such as newborn infants’ visual preference for face-like over non-face stimuli. The role of experience and the process of perceptual narrowing in face processing are examined as infants begin to demonstrate enhanced behavioral and neural responsiveness to mother over stranger, female over male, own- over other-race, and native over non-native faces. Next, we cover research on developmental change in infants’ neural responsiveness to faces in multimodal contexts, such as audiovisual speech. We also explore the potential influence of arousal and attention on early perceptual preferences for faces. Lastly, the potential influence of the development of attention systems in the brain on social-cognitive processing is discussed. In conclusion, we interpret the findings under the framework of Developmental Systems Theory, emphasizing the combined and distributed influence of several factors, both internal (e.g., arousal, neural development) and external (e.g., early social experience) to the developing child, in the emergence of attentional biases that lead to enhanced responsiveness and processing of faces commonly encountered in the native environment.

Visual Working Memory in Early Development: A Developmental Cognitive Neuroscience Perspective

In this article, we review the literature on the development of visual working memory (VWM). We focus on two major periods of development, infancy and early childhood. First, we discuss the innovative methods that have been devised to understand how the development of selective attention and perception provide the foundation of VWM abilities. We detail the behavioral and neural data associated with the development of VWM during infancy. Next, we discuss various signatures of development in VWM during early childhood in the context of spatial and featural memory processes. We focus on the developmental transition to more adult-like VWM properties. Finally, we discuss computational frameworks that have explained the complex patterns of behavior observed in VWM tasks from infancy to adulthood and attempt to explain links between measures of infant VWM and childhood VWM.