Gregory J. Renner

Outcome analysis for lip carcinoma

Carcinoma of the lip is a relatively common malignancy of the head and neck region, accounting for approximately one quarter of oral cavity cancers. Although this form of cancer is generally readily curable compared with malignancies at other head and neck sites, regional metastases, local recurrence, and even death from this disease may occasionally occur. A review of 1252 patients who were diagnosed with lip cancer from 1940 to 1987 was undertaken to identify and rank prognostic variables, clarify differential incidences of site predilection between male and female patients, and examine the correlation between tumor site and histopathologic diagnoses. Large tumor size, high tumor grade, the presence of adenopathy, a subsite other than the lower lip, and inadequate surgical margins were found to have a negative impact on determinate survival of patients with lip carcinoma. Twenty-one percent of lip cancers in female patients arose on the upper Up, whereas only 3% of lip cancers in male patients developed on the upper lip. Basal cell carcinomas comprised 13% of upper lip cancers and only less than 1% of lower lip cancers. Recurrence developed in 15.1% of the patients reviewed and was strongly associated with large tumor size and poor differentiation. Local recurrence was associated with a determinate survival of 78%, whereas patients having regional recurrences had a survival rate of 52%. These data support aggressive treatment of lip cancers greater than 3 cm in diameter, high-grade tumors, tumors associated with cervical lymphadenopathy, and upper lip and commissure tumors. Lip cancer in women seems to be slightly more aggressive than in men.

Intraoperative radiolymphoscintigraphy for detection of occult nodal metastasis in patients with head and neck squamous cell carcinoma.

OBJECTIVES: We sought to determine the feasibility and utility of intraoperative radiolymphoscintigraphy as a screening procedure for the detection of occult metastatic disease in selected cases of head and neck squamous cell carcinoma (HNSCC). METHODS: Patients with accessible primary HNSCC and no evidence of metastatic disease who were already undergoing planned surgical resection of the primary tumor and elective neck dissection met the inclusion criteria. Before resection, a handheld gamma probe was used to find the radiolabeled sentinel lymph node (SLN). The neck specimen was examined ex vivo by using the gamma probe; the SLN or SLNs were dissected free from the specimen and sent separately for histopathologic examination. RESULTS: At least one SLN was identified in all patients enrolled thus far. Four patients had microscopic carcinoma found in the SLN. Two of these had cancer only in the SLN, and two had disease both in the SLN and the remaining specimen. CONCLUSIONS: Intraoperative radiolymphoscintigraphy appears to be a feasible and promising procedure to aid the surgeon in more accurately detecting occult metastatic HNSCC.

Secondary and metastatic tumors of the orbit.

We have presented three cases of metastatic tumor to the orbit. The first case illustrated metastatic tumor that originated from a cutaneous basosquamous cell carcinoma. This lesion, first reported by MacCormac as being morphologically intermediate between basal and squamous cell carcinoma, has become a topic of some controversy. Conley reported these tumors to represent 1% of basal cell carcinomas. Several authors have reported a higher incidence of recurrence with these lesions, as compared with the ordinary basal cell tumors. Recurrence of basal cell carcinomas are reported as approximately 10%, but are four times greater in the basosquamous cell tumors. The incidence of metastasis with the basosquamous cell tumors has been reported in between 37% and 51% of cases. The second case represented involvement of the orbit by direct extension of a facial squamous cell carcinoma. As illustrated by this case, these tumors can be very aggressive and should be treated with respect. The third case showed the metastatic potential of the nephroblastoma with metastatic tumor that involved the eye, orbit, and maxilla. Diagnostic techniques available in evaluation of these tumors include CT scan, magnetic resonance (MR) imaging, ultrasound, open biopsy, and fine-needle aspiration. Li et al., in an article that compared MR imaging, CT scan, and ultrasound concluded that MR imaging, with the use of the 0.15 T resistive magnet, offered no distinct advantage over the combination of CT and ultrasound in evaluation of patients with orbital tumors.(ABSTRACT TRUNCATED AT 250 WORDS)

Deep Neck Abscess after Tracheoesophageal Puncture and Insertion of a Voice Button Prosthesis

A deep neck abscess and cervical osteomyelitis developed in a 37-year-old laryngectomy patient 6 weeks after TE puncture and insertion of a voice button prosthesis. This complication resulted in voice prosthesis failure, multiple surgical procedures, 83 days of hospitalization while receiving parenteral antibiotics, and exposure to potentially fatal complications. Some factors contributing to this problem may include an improperly fitting prosthesis, rough insertion of the prosthesis, and altered tissue response to infection from radiation therapy and surgery.

Temporalis pericranial muscle flap for reconstruction of the lateral face and head

Large ablative surgical tissue defects of the lateral face and head can pose a difficult task for the reconstructive surgeon who must choose from among a large variety of possible reparativce techniques. In many situations the temporalis pericranial muscle flap offers the outstanding feature of providing a large amount of soft tissue at no direct expense of donor site skin cover. It is easily obtained and results in negligible functional loss. With care taken to preserve the neurovascular pedicle, this flap may be rotated in multiple directions and even overturned as either surface can receive surface skin closure. The amount of operative time and effort required is much less than for many of the more elaborate reconstructive flaps. Five representative cases are presented.

Pilot study to evaluate the efficacy of hyperbaric oxygen therapy in improving the survival of reattached auricular composite grafts in the New Zealand White rabbit.

OBJECTIVE: This investigation is a prospective, randomized, blinded study seeking to evaluate the efficacy of hyperbaric oxygen (HBO) therapy in improving the survival of the reattached auricular composite graft. STUDY DESIGN: Twenty New Zealand White rabbits were randomly assigned to control (10) and treatment (10) groups in a prospective fashion. After amputation and reattachment of measured segments of each ear, the treatment group received 14 HBO treatments for 10 days. The control group received only standard postoperative care. On postoperative day 18, the surviving composite grafts were measured, recorded, and statistically analyzed. RESULTS: The mean percentage of graft survival for the control group was 0.31% (range 0%-2.5%), and the mean for the group receiving HBO was 15.94% (range 0%-38%). A median test was used to evaluate this difference, which was found to be statistically significant (P = 0057). CONCLUSION: Our study appears to indicate a possible survival benefit for the composite grafts in those rabbits that received HBO treatments. We believe that there are several significant difficulties with the rabbit as a model for this study, but we are encouraged at this point that a limited measurable benefit was observed. Further investigations with HBO appear to be warranted at this time.

Bilateral aberrant internal carotid arteries.

This case report represents the first well-documented case of aberrant internal carotid arteries in both middle ears. CT and DSA can establish the diagnosis before surgical intervention. Aberrant internal carotid artery represents a rare finding in the differential diagnosis of middle ear masses. Most patients manifest either vertigo, tinnitus, or a variable hearing loss. Clinical findings include a red or blue mass behind the eardrum that may or may not be pulsatile. The otolaryngologist should be aware that this potential landmine may be obscured by serous otitis media. Once suspected, the mass should be evaluated by radiographic studies before surgical intervention.

Double-Doyle Intranasal Airway Splint Technique

Objective: Present a novel technique utilized by the senior author for support of unstable, comminuted nasal bone fractures and its adaptation to rhinoplasty and septal surgery to provide greater stabilization of the nasal septum and bones. Illustrate safe and adequate results with this technique. Method: Retrospective chart review of the senior author’s past surgical procedures since 2001 utilizing this Double-Doyle intranasal airway splint technique. Patient demographics, diagnoses, surgical procedure, stenting duration, and complications were identified. This technique involves 2 modified Doyle II intranasal airway splints (Medtronic) to provide greater intranasal support. Results: Eighty-seven cases involving the Double-Doyle intranasal airway splint technique performed for closed nasal reduction, selected cases of open rhinoplasty, and septal procedures revealed overall that this intranasal splint modification was safe, tolerated well by patients, and presented minimal morbidity. All but one patient experienced a successful cosmetic and functional outcome as described by the senior author. Six overall possible complications were noted; 3c cases of minor nasal mucosa damage and 3c cases of possible infection that resolved after removal of the splint and treatment with antibiotics. Conclusion: We present a safe technique that provides prolonged nasal dorsal support in severely comminuted nasal bone fractures without the need for external suspension devices or additional incisions. Additionally, this technique may be applied to rhinoplasty and septal procedures involving significant septal correction to allow greater stabilization of the septum postoperatively.

Nasal spine suspension for reduction and immobilization of mandibular fractures.

Successful treatment of mandibular fractures involves proper fracture reduction and immobilization for an adequate length of time. A simple wire fixation technique that can be used in many situations involves suspension wiring from the base of the anterior nasal spine to a pair of circummandibular wires. The technique may be used alone or adjunctively with other methods of fixation. It offers several advantages over other methods, particularly in the treatment of pediatric mandibular fractures.

Postauricular epidermoid cysts: treatment with electric current.

We believe the use of electric current to treat epidermoid inclusion cysts in the postauricular area is a simple, effective method that results generally in prolonged decompression of the cyst. The length of time that the fistula remains patent is unknown at present. Local control is, however, prolonged and may be permanent. Over time the induration subsides and the sac atrophies.