Guido Lombardo
University of Perugia
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Guido Lombardo.
Journal of Dentistry | 2012
Manila Chieruzzi; Stefano Pagano; Manuela Pennacchi; Guido Lombardo; Potito D’Errico; J. M. Kenny
OBJECTIVES The aim of this study was to investigate the mechanical properties of five types of fibre-reinforced composite (FRC) posts and compare them with traditional metal post. METHODS Five FRC posts and a metallic post having different geometry and type of fibre (glass, carbon or quartz fibre) were loaded to failure in compression and bending. The transverse sections of FRC posts were observed using SEM to evaluate the fracture mode and the percentage of fibres (compared with burn-off test). Densities and voids content were also evaluated. RESULTS Mechanical results were subjected to a one-way ANOVA and Tukey test (p<0.05). In compression, quartz fibre posts exhibited the greater maximum load and ultimate strength, carbon fibre posts showed a poor compressive behaviour. All posts had similar compressive moduli. Carbon posts showed the highest flexural properties (p<0.0001) while glass posts the greater maximum load. The fracture load values correlated to the diameters of posts showed a parabolic behaviour. The flexural strengths of all posts were four and seven times higher than dentine. The elastic moduli of almost all posts were similar to dentine. The compressive strengths were lower than flexural strengths. The fibre diameters ranged from 5.2 to 26 μm, the volume percentage of fibres was about 64%. The content of voids of some posts lower their mechanical behaviour. CONCLUSIONS Compressive properties of FRC posts were lower than in bending. The flexural properties of FRC posts were higher than the metal post and similar to dentine. The mechanical behaviour is influenced by voids.
Journal of Clinical Epidemiology | 2017
Iosief Abraha; Francesco Cozzolino; Massimiliano Orso; Mauro Marchesi; Antonella Germani; Guido Lombardo; Paolo Eusebi; Rita De Florio; Maria Laura Luchetta; Alfonso Iorio; Alessandro Montedori
OBJECTIVES To describe the characteristics, and estimate the incidence, of trials included in systematic reviews deviating from the intention-to-treat (ITT) principle. STUDY DESIGN AND SETTING A 5% random sample of reviews were selected (Medline 2006-2010). Trials from reviews were classified based on the ITT: (1) ITT trials (trials reporting standard ITT analyses); (2) modified ITT (mITT) trials (modified ITT; trials deviating from standard ITT); or (3) no ITT trials. RESULTS Of 222 reviews, 81 (36%) included at least one mITT trial. Reviews with mITT trials were more likely to contain trials that used placebo, that investigated drugs, and that reported favorable results. The incidence of reviews with mITT trial ranged from 29% (17/58) to 48% (23/48). Of the 2,349 trials, 597 (25.4%) were classified as ITT trials, 323 (13.8%) as mITT trials, and 1,429 (60.8%) as no ITT trials. The mITT trials were more likely to have reported exclusions compared to studies classified as ITT trials and to have received funding. CONCLUSION The reporting of the type of ITT may differ according to the clinical area and the type of intervention. Deviation from ITT in randomized controlled trials is a widespread phenomenon that significantly affects systematic reviews.
Materials Science and Engineering: C | 2017
Manila Chieruzzi; Stefano Pagano; Stefano Cianetti; Guido Lombardo; J. M. Kenny; Luigi Torre
The aim of this work was to evaluate the stress distribution inside endodontically treated teeth restored with different posts (glass fibre, carbon fibre and steel posts) under different loading conditions by using a 3D-finite element analysis. The effect of masticatory and impact forces on teeth with different degrees of bone loss was analysed. The model consists of: dentine, post, cement, gutta-percha, core and crown. Four simulations were conducted with two static forces (170N horizontal and 100N oblique) and two sections constrained: 1mm (alveolar bone position in a normal periodontium) and 6mm (middle of root) below the crown. Von Mises and the principal stresses were evaluated and analysed with a 3-way ANOVA and Tukey test (α=0.05) and the effect of fibre percentage analysed. Significant differences were found among the stress values for all conditions (p<0.05). Impact load was always responsible for the most critical situation especially when the bone loss was more evident. The system with steel posts showed the highest principal stresses at the post-cement interface with horizontal load and top constraints (compressive stress of 121MPa and tensile stress of 115MPa). The use of glass posts provides a more homogeneous behaviour of the system with lower stresses. Higher fibre percentages gave higher stress in the posts. Moreover, larger bone losses are responsible for important increase in stress. Thus, this work demonstrated that periodontal disease has an important role in the success of tooth restoration after endodontic therapy, influencing the choice of post material and depth.
BMJ Open | 2018
Stefano Cianetti; Iosief Abraha; Stefano Pagano; Eleonora Lupatelli; Guido Lombardo
Objectives To evaluate the effectiveness and degree of acceptance by children and adolescents of the use of oscillating tips compared with rotating drills. Design Systematic review. Data sources PubMed, the Cochrane Central Register of Controlled Trials (CENTRAL), the Cochrane Library and Web of Science (October 2017). Eligibility criteria Controlled randomised or non-randomised trials that evaluated sonic and ultrasonic oscillating devices versus rotating drill. Data extraction Eligible studies were selected and data extracted independently by two reviewers. Risk of bias was assessed using the Cochrane Method. Results Two controlled clinical trials comprising 123 children aged 2–12 years old were identified. Both trials were at high risk of selection bias and unclear risk of detection bias. In one trial, pain due to the use of oscillating drill resulted lower than employing rotating drill (Verbal Hochman Scale: RR 0.64 (95% CI 0.41 to 1.00); Visual Facial Expression Scale: RR 0.64 (95% CI 0.44 to 0.94)). In another study, compared with traditional drill ultrasonic tip was associated with a lower level of patient’s discomfort (RR 0.40 (95% CI 0.20 to 0.79)) but not with dental anxiety (RR 1.29 (95% CI 0.97 to 1.71)). The effectiveness of the removal of caries as well as fillings durability were only considered in one study, but no statistically significant differences were found between the two interventions. Conclusions The evidence based on two low-quality studies was insufficient to conclude that the use of oscillating tips for the management of pain and dental fear in children or adolescents compared with rotating drills was more effective.
Cochrane Database of Systematic Reviews | 2017
Robert P. Anthonappa; Paul Ashley; Debbie Bonetti; Guido Lombardo; Philip Riley
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: This review aims to assess the effectiveness of non-pharmacological interventions for reducing dental anxiety in children.
Materials Science and Engineering: C | 2019
Stefano Pagano; Manila Chieruzzi; Stefania Balloni; Guido Lombardo; Luigi Torre; Maria Bodo; Stefano Cianetti; Lorella Marinucci
The study evaluated the effects of 4 wt% nanohydroxyapatite (HA), 6 wt% zinc l-carnosine (MDA) and 1.5 wt% Ciprofloxacin (AB) on the mechanical, thermal and biological properties of glass ionomer cements (GIC). Filler and additive concentrations were selected after a previous study had tested single components and different percentages. Specimens included five silicon molds of each GIC cement for all tests. They were stored at room temperature for 24 h from specimen collection to analysis. Mechanical tests, calorimetric analysis, morphological investigation, antibacterial and cell viability assays were conducted. One-way analysis of variance (ANOVA) was used for data analysis with significance set at p < 0.05. Adding HA, MDA and AB to GICs modified their thermal, mechanical and microbiological properties. Polymerization increased. A slight decrease in the compressive strength of modified GICs was observed in dry condition (p < 0.05). Cement extracts affected cell viability in relation to extract dilution. Mechanical behavior improved in modified glass ionomer cements, especially with the powder formulated antibiotic. Overall cytotoxicity was reduced. Therefore adding nanohydroxyapatite, antibiotic and a mucosal defensive agent to conventional glass ionomer cement in special need patients could improve the clinical, preventive and therapeutic performance of the cements, without altering their mechanical properties.
Dental Cadmos | 2016
Stefano Pagano; B. Pomili; M. Verso; Guido Lombardo; G. Barraco; G. Agnelli; Stefano Cianetti
Riassunto Obiettivi Scopo dello studio e valutare le implicazioni dei nuovi anticoagulanti orali (Novel Oral Anticoagulants, NOA) nelle terapie odontoiatriche, alla luce della recente letteratura. Materiali e metodi E stata eseguita una valutazione comparativa degli studi condotti negli ultimi cinque anni per confrontare gli effetti dei NOA rispetto agli anticoagulanti tradizionali nelle procedure odontoiatriche. Risultati Rapidita d’azione, minori interazioni farmacologiche ed esigenza di monitoraggio non continuo renderebbero i NOA vantaggiosi rispetto agli anticoagulanti tradizionali. Ulteriori indagini sono tuttavia necessarie. Conclusioni La letteratura conferma la possibilita di mantenere la terapia con i NOA durante le principali procedure odontoiatriche. Importante e definire specifici criteri clinici.
Cochrane Database of Systematic Reviews | 2016
Alessandro Montedori; Iosief Abraha; Massimiliano Orso; Potito D'Errico; Stefano Pagano; Guido Lombardo
Journal of Materials Research | 2018
Manila Chieruzzi; Stefano Pagano; Guido Lombardo; Lorella Marinucci; J. M. Kenny; Luigi Torre; Stefano Cianetti
Dental Cadmos | 2014
Stefano Cianetti; A. Fioroni; M. Marinelli; Guido Lombardo