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Featured researches published by Guilherme Saito.


Foot & Ankle International | 2018

Short-Term Complications, Reoperations, and Radiographic Outcomes of a New Fixed-Bearing Total Ankle Arthroplasty

Guilherme Saito; Austin Sanders; Cesar de Cesar Netto; Martin J. O’Malley; Scott J. Ellis; Constantine A. Demetracopoulos

Background: With the increasing use of total ankle arthroplasty (TAA), new implants with varied configurations are being developed every year. This study aimed to assess the early complications, reoperations, and radiographic and clinical outcomes of the Infinity TAA. To date, clinical results of this novel implant have not been published. Methods: A retrospective analysis of 64 consecutive ankles that underwent a primary Infinity TAA from July 2014 to April 2016 was performed. Patients had an average follow-up of 24.5 (range, 18-39) months. Medical records were reviewed to determine the incidence of complications, reoperations, and revisions. Radiographic outcomes included preoperative and postoperative tibiotalar alignment, tibial implant positioning, the presence of periprosthetic radiolucency and cysts, and evidence of subsidence or loosening. Additionally, patient-reported outcomes were analyzed with the Foot and Ankle Outcome Score (FAOS). Results: Survivorship of the implant was 95.3%. Fourteen ankles (21.8%) presented a total of 17 complications. A total of 12 reoperations were necessary in 11 ankles (17.1%). Revision surgery was indicated for 3 ankles (4.7%) as a result of subsidence of the implant. Tibiotalar coronal deformity was significantly improved after surgery (P < .0001) and maintained during latest follow-up (P = .81). Periprosthetic radiolucent lines were observed around the tibial component in 20 ankles (31%) and around the talar component in 2 ankles (3.1%). A tibial cyst was observed in 1 ankle (1.5%). Outcome scores were significantly improved for all FAOS components analyzed (P < .0001), from 39.0 to 83.3 for pain, from 34.0 to 65.2 for symptoms, from 52.3 to 87.5 for activities of daily living, and from 15.7 to 64.2 for quality of life. Conclusion: Most complications observed in the study were minor and successfully treated with a single reoperation procedure or nonoperatively. Failures and radiographic abnormalities were most commonly related to the tibial implant. Further studies with longer follow-up are needed to evaluate the survivorship of the tibial implant in the long term. Level of evidence: Level IV, retrospective case series.


Journal of Foot & Ankle Surgery | 2018

Open Re-rupture of the Achilles Tendon Following Minimally Invasive Repair: A Case Report

Cesar de Cesar Netto; Alessio Bernasconi; Lauren Roberts; Guilherme Saito; William G. Hamilton; Martin J. O'Malley

In this report, we describe a rare complication of an open re-rupture of the Achilles tendon following a minimally invasive Achilles tendon repair on a healthy 29-year-old active male. The reinjury happened 19 weeks following the primary surgical repair of a spontaneous rupture, performed by minimally invasive technique with the help of a jig using partially absorbable sutures and four locking stitches. The wound of the open re-rupture was transverse, in a perpendicular orientation relative to the longitudinal approach used in the index procedure. Increased scar tissue formation, the absence of an adequate layer of paratenon overlying the primary tendon repair, and foreign-body reaction to the suture may have been involved in the occurrence of this unusual complication in the surgical treatment of Achilles tendon rupture.


Foot and Ankle Surgery | 2018

Accuracy of patient-specific instrumentation in total ankle arthroplasty: A comparative study

Guilherme Saito; Austin Sanders; Martin J. O’Malley; Jonathan T. Deland; Scott J. Ellis; Constantine A. Demetracopoulos

BACKGROUNDnPatient-specific instrumentation (PSI) for TAA is a novel technology with several potential benefits. The primary goal of this study was to compare the use of PSI with the standard referencing guide (SRG) in regards to accuracy of tibial implant positioning. Operative time, fluoroscopy time and accuracy of PSI preoperative reports were also evaluated.nnnMETHODSnA retrospective analysis of 99 patients who underwent a primary TAA with the INFINITY prosthesis (Wright Medical, Memphis, TN) was performed. Patients were divided in two groups based on the type of instrumentation used during the TAA (75 in the PSI group vs 24 in the SRG group). There was no significant difference between groups in regards to age at the time of surgery (P=0.122), sex (P=0.138), number of concomitant procedures performed during surgery (P=0.567) and etiology (P=0.841). However, preoperative deformity was significantly smaller in the PSI group (P=0.002).nnnRESULTSnTibial implant positioning was similar between groups. In the coronal plane, the absolute deviation of the tibial implant from the intended alignment was 1.7±1.4° for the SRG and 1.6±1.2° for PSI (P=0.710). In the sagittal plane, the absolute alignment deviation of the tibial implant was 1.8±1.4° for the SRG and 1.9±1.5° for PSI (P=0.675). Operative time (167 vs 190min, P=0.040) and fluoroscopy time (85 vs 158s, P<0.001) were significantly decreased in the PSI group. The PSI preoperative plan report correctly predicted the implant size in 73% of cases for the tibial component and in 51% of cases for the talar component.nnnCONCLUSIONSnPSI provided similar tibial component alignment as standard instrumentation. Additionally, PSI preoperative plan reports were poor predictors of implant sizing. Therefore, the final decision should always be based on surgeons experience in order to prevent errors in implant sizing and positioning.nnnLEVEL OF EVIDENCEnLevel III, retrospective comparative study.


Foot & Ankle Orthopaedics | 2018

Influence of Tibial Component Position on Altered Kinematics Following Total Ankle Arthroplasty During Simulated Gait

Guilherme Saito; Daniel R. Sturnick; Jonathan T. Deland; Scott J. Ellis; Constantine A. Demetracopoulos

Introduction/Purpose: Correct positioning of total ankle arthroplasty (TAA) implants has been associated with superior clinical outcomes. Furthermore, biomechanical studies have demonstrated that poor alignment of the components may lead to early component wear, compromising the longevity of the prosthesis. Malpositioning of TAA implants affects ligament engagement patterns and joint contact mechanics, possibly leading to altered joint kinematics. However, the correlation between implant position and ankle joint motion is still unclear. The objective of this study was to assess the effect of tibial component position on ankle kinematics following TAA during simulated gait.


Techniques in Foot & Ankle Surgery | 2017

Use of CT Scan-derived Patient-specific Instrumentation in Total Ankle Arthroplasty

Guilherme Saito; Austin Sanders; Daniel R. Sturnick; Constantine A. Demetracopoulos

Abstract: Total ankle arthroplasty has evolved significantly in the last 2 decades. Improvements in surgical technique and instrumentation, as well as advances in implant design, have contributed significantly to the increased adoption of ankle replacement for the treatment of ankle arthritis. Achieving proper alignment and correct positioning of the components is critical for the function and survivorship of the prosthesis. Patient-specific instrumentation generated by preoperative computed tomography is a tool which may allow for more reliable and reproducible component positioning. This article will provide a brief review of the technique and our early results of utilizing patient-specific instrumentation in total ankle arthroplasty. Level of Evidence: Diagnostic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Foot & Ankle Orthopaedics | 2017

The Function Axis of Rotation of the Ankle Joint during Simulated Gait

Daniel R. Sturnick; Constantine A. Demetracopoulos; Guilherme Saito

Category: Ankle, Ankle Arthritis, Hindfoot Introduction/Purpose: Implant component positioning is considered as an important factor in function and longevity in total ankle arthroplasty (TAA). However, accurate and repeatable positioning remains a limitation with current techniques and instrumentation. In addition, further investigation is needed to objectively define the optimum component positioning. Cadaveric gait simulation is a valuable tool for investigating foot and ankle joint mechanics during functional tasks such as the stance phase of gait. The objective of this study was to investigate the functional axis of rotation of the native ankle joint during simulated gait. Methods: The stance phase of healthy gait was simulated with six mid-tibia cadaveric specimens using a previously validated device and methodology. A robotic platform reproduced tibial-ground kinematics by moving a force plate relative to the stationary specimen while physiologic loads were applied to the extrinsic tendons to actuate the foot. (Figure 1A). Ankle kinematics were measured from reflective markers attached to the tibia and talus via surgical pins. The helical axes of rotation of the talus with respect to the tibia was calculated during three portions of stance: initial plantarflexion during earlier-stance after heal strike, dorsiflexion during mid-stance, and final plantarflexion during late-stance. The position and orientation of these kinematic-defined axes of rotation were compared to the transmalleolar axis and reduced to its anteroposterior position and transverse plane angle (Figure 1B). Results: Analyses revealed that ankle joint functional axis of rotation varied from the anatomic reference throughout stance. The kinematic center of rotation was located 16.4 ± 5.8 mm, 16.5 ± 6.6 mm, and 15.6 ± 6.5 mm anterior to the transmalleolar axis during early-, mid- and late-portions of stance, respectively. Conclusion: This study revealed that the position of the flexion-extension axis varies greatly between specimens during simulated gait. While previous reports have suggested that the transmalleolar axis is an acceptable approximation for the ankle joint center, these findings suggest that further research in warranted to better describe the complex tibiotalar kinematics. This work may provide future insight to guide implant design and advance techniques, to better place articular constraints of a total ankle in the native center of rotation of the joint.


Techniques in Foot & Ankle Surgery | 2018

Total Ankle Replacement With Advanced Varus and Valgus Deformities

Guilherme Saito; Austin Sanders; Constantine A. Demetracopoulos


Foot & Ankle Orthopaedics | 2018

Short-term Complications, Reoperations, and Radiographic Outcomes of the Infinity Total Ankle Arthroplasty

Guilherme Saito; Austin Sanders; Cesar de Cesar Netto; Martin J. O’Malley; Scott J. Ellis; Constantine A. Demetracopoulos


Foot & Ankle Orthopaedics | 2018

Ankle and Hindfoot Kinematics of a Next Generation Total Ankle Replacement During Simulated Gait

Daniel R. Sturnick; Guilherme Saito; Scott J. Ellis; Constantine A. Demetracopoulos


Foot & Ankle Orthopaedics | 2018

Finite Element Analysis of Tibial Bone-Implant Load Transfer and Bone Strains with a Modern Fixed-bearing Total Ankle Replacement

Daniel R. Sturnick; Guilherme Saito; Jonathan T. Deland; Constantine A. Demetracopoulos; Xiang Chen; Susan Rodriguez

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Daniel R. Sturnick

Hospital for Special Surgery

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Scott J. Ellis

Hospital for Special Surgery

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Austin Sanders

Hospital for Special Surgery

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Jonathan T. Deland

Hospital for Special Surgery

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Martin J. O’Malley

Hospital for Special Surgery

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Lauren Roberts

Hospital for Special Surgery

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Alessio Bernasconi

Hospital for Special Surgery

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