Gul Sagin Saylam

Development of right ventricular outflow tract obstruction after double-lung transplantation for primary pulmonary hypertension

We present a patient with primary pulmonary hypertension who had unusually high pulmonary arterial pressure prior to double-lung transplantation. Obstruction of the right ventricular outflow tract developed after transplantation and progressed over the subsequent two years.

SURVIVAL ANALYSIS FROM THALES STUDY, A LARGE NATION-WIDE REGISTRY ON PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH CONGENITAL HEART DISEASE

Background: Baseline data from the national, multicenter, prospective, observational THALES Registry providing information regarding demographic and clinical characteristics and treatment patterns had previously reported. In this analysis, we aim to assess survival in association with clinical,

THE QUANTIFICATION OF FUNCTIONAL CLASS AND THE SIX-MINUTE WALKING DISTANCE IN PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH CONGENITAL SHUNTS: CLINICAL AND HEMODYNAMIC CORRELATES

The definition of WHO functional class (FC) is mainly based on the semi-quantitative evaluation of exertion capacity and clinical symptoms, and therefore lacks objectivity in its use for PAH associated with congenital heart disease (APAH-CHD). To overcome this limitation, we explored a quantitative

Total correction of tetralogy of Fallot without “routine”preoperative cardiac catheterization—management of 99 patients

Between January 1989 and March 1993, total correction was performed in 99 patients with tetralogy of Fallot without submitting them to prior cardiac catheterization. The age of the patients ranged from 1.33 to 18 years (mean 5.33±3.77). After complete echocardiographic examination, the diameters of the right and left pulmonary arteries at the prebranching point and the descending thoracic aorta at the diaphragm were measured by cross-sectional echocardiography and the McGoon ratio was calculated. Total correction was performed in all patients with a McGoon ratio greater than 1.7. In none of the patients were the sizes of the pulmonary artery measured by echocardiography smaller than the measurements obtained during surgery. Transannular patching was performed in 76 patients. A conduit from the right ventricle to the pulmonary arteries was constructed in two patients with coronary arterial anomalies. Postrepair right ventricular to left ventricular systolic pressure ratios were between 0.25 and 0.85 (mean 0.54±0.13). There were two hospital deaths, neither being related to the diagnostic method used nor the criteria for surgery. We conclude that the diagnosis of tetralogy of Fallot together with measurements of pulmonary arteries and descending thoracic aorta can safely and reliably be achieved echocardiographically. The McGoon ratio can be adapted to echocardiography and total correction can be performed successfully based on echocardiographic examination.